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Pretreatment geriatric nutritional risk index, survival, and PD-L1 expression in muscle-invasive bladder cancer treated with neoadjuvant chemotherapy followed by radical cystectomy

在接受新辅助化疗后行根治性膀胱切除术的肌肉浸润性膀胱癌患者中,高水平的治疗前老年营养风险指数(GNRI)是总生存期改善的独立预测因子,并与残余肿瘤中较高的 PD-L1 表达相关,尽管这种预后获益似乎独立于 PD-L1 介导的机制而发挥作用。

Maria Aoki, Taku Naiki, Aya Naiki-Ito, Yosuke Sugiyama, Nobuhiko Shimizu, Toshiharu Morikawa, Takashi Nagai, Keitaro Iid (…)2026-07-25
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Three-Dimensional Spinal Cord Volume Mobility on Dynamic Cervical CT Myelography Is Associated With Postoperative Neurological Recovery in Cervical Spondylotic Myelopathy

这项前瞻性研究表明,通过动态颈椎CT脊髓造影获得的更大三维脊髓体积运动性(SCVM),与颈椎病性脊髓病患者较差的长期神经功能恢复显著相关,为传统的单层横截面积测量提供了一个有价值的补充指标。

Jiuheng Li, Jinchao Wang, Chao Wang, Ning Zhang, Yuetao Zhu, Qingpeng Song, Xiaohan Zhao, Yuqing Yang, Zhichen Jiang, Xi (…)2026-07-25
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Selective Nerve Block-Guided Unilateral Biportal Endoscopic Bilateral T10 Rhizotomy for Refractory Intercostal Neuralgia Caused by Cement Leakage after Percutaneous Vertebroplasty: A Case Report and Literature Review

本病例报告表明,选择性神经阻滞可以有效定位由椎体成形术后胸椎骨水泥泄漏引起的难治性肋间神经痛中的症状性神经根,从而使以单侧双通道内镜下双侧T10神经根切断术作为针对性补救手术能够取得成功的结果。

Fuxin Wang, Zheng Zhang, Xin Xu, Le Shen, Xinmei Li, Ruoxian Song2026-07-25
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Effect of transcranial direct current stimulation combined with virtual reality on lower-limb function and balance in patients during convalescent stroke recovery

这项随机、双盲、伪刺激对照试验表明,将经颅直流电刺激(tDCS)与虚拟现实训练相结合,通过提高皮层兴奋性并缩短中枢运动传导时间,比单纯使用虚拟现实更有效地显著增强了卒中后患者的下肢运动功能、平衡能力和日常生活活动能力。

Xinbao Tian, Menglai Hao, Fubao Tian, Yuanyuan Liu, Yongyi Yuan, Weidong Jin, Yindi Bai, Ruizhu Lin2026-07-25
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The Double Minority Penalty? Ethnicity, Sect and the Criminalisation of Border Livelihoods in Iran

本文认为,伊朗的库尔德逊尼派边境地区正经历着“双重少数群体惩罚”和“国家制造的非法性”,即宪法规定的什叶派主导地位和限制性的经济政策,将诸如“科尔巴里”(kolbari)之类的日常生存策略转化为犯罪行为,从而为针对这些边缘化群体的致命性国家强制手段提供了正当理由。

Hamoon Khelghat-Doost2026-07-25
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Visualizing the Future: Impact of Holographic Visualization on Teaching Minimally Invasive Veneer Preparation: A Randomized Controlled Trial

这项随机对照试验发现,虽然与传统的二维照片相比,全息可视化并未显著提高微创贴面备牙的即时技术质量,但它受到了学生的高度认可,并在增强临床前修复学教育中的感知空间理解方面展现出最大的潜力。

Malin Janson, Maximilian Louis Lederer, Christina Dalhoff, Anna Greta Barbe, Anja Liebermann, Christoph Matthias Schoppm (…)2026-07-25