Unifying the statistical foundations of variant and methylation calling for enabling sequencing platform and calling scenario independence within Varlociraptor
本文在 Varlociraptor 框架内提出了一种广义贝叶斯统计框架,该框架统一了跨多种测序平台的遗传变异检测与甲基化率分析,从而实现了对基因组和表观基因组数据更准确、具备不确定性感知且联合的分析。