Canine splenic lesions: epidemiological patterns and the predictive value of hemoperitoneum for malignancy
This retrospective study of 228 dogs undergoing splenectomy reveals that while hemoperitoneum is a strong predictor of splenic malignancy, particularly hemangiosarcoma, the overall near-equal distribution of neoplastic and non-neoplastic lesions challenges the traditional "two-thirds rule" regarding the prevalence of cancer in canine splenic masses.