280 papers
Bioengineering sits at the vibrant intersection of biology and engineering, where scientists design new tools to understand life and solve real-world problems. From creating artificial organs to developing smart materials that mimic natural tissues, this field turns complex biological questions into tangible innovations that improve human health and our environment.
At Gist.Science, we track every new preprint in this category directly from bioRxiv. Our team processes each submission to provide both plain-language explanations for curious minds and detailed technical summaries for researchers, ensuring these cutting-edge discoveries are accessible to everyone. Below are the latest papers in bioengineering that have recently appeared on bioRxiv.
This study proposes a conceptual inversion of the traditional view of substrate crossover in microbial fuel cells, introducing a transport-reaction modeling framework that reframes controlled cathode-to-anode substrate flux as a passive mechanism to sustain biofilm metabolism and enable long-term autonomous operation.
This paper introduces Layer-wise Image Trajectories (LIT), an in situ monitoring method that analyzes coaxial image comparisons during two-photon polymerization to predict fabrication quality and detect anomalies early in the build process for both acellular and cell-laden hydrogels, overcoming the limitations of traditional post-processing evaluation.
This paper presents the first open-source sensory benchmark from the NECTAR 2026 study, which evaluates 112 commercial dairy-free products against dairy counterparts across ten categories to demonstrate that sensory parity is achievable in beverages while identifying specific flavor and texture deficits in solid dairy alternatives that offer key opportunities for future innovation.
This study re-examines the lower speed boundary of preferred coordination ratio constancy using published data and demonstrates that the previously reported 62 m/min threshold is not a single dominant breakpoint but rather one of several competing regions, with alternative statistical models suggesting the true boundary may lie significantly lower.
This study adapts a programmable flow-based in vitro platform to decouple the accuracy of generated glucose profiles from the dynamic response of continuous glucose monitoring (CGM) systems, proposing a novel set of metrics that decompose dynamic error into amplitude, rate, shape, and hysteresis components to reveal performance limitations obscured by traditional summary statistics like MARD.
This paper proposes and validates a mechanical theory demonstrating that local stress fields generated by cortical folding guide the reorientation of growing axons, thereby explaining the preferential formation of U-shaped short association fibers between gyri.
The authors present the "Cell Trainer," an open-source automated platform that utilizes timed drug pulses and real-time feedback control to study adaptive learning and memory-like behaviors in non-neural mammalian cells, thereby bridging gaps in understanding cellular physiological plasticity.
This paper introduces a cuffed CRISPR guide RNA (cgRNA) system that enables miRNA activity-dependent genome editing, allowing for cell state-specific gene modulation, miRNA activity mapping, and the irreversible recording of molecular cell states.
This study evaluated the feasibility of using the crossmodal congruency task to measure the intuitiveness of sensory feedback in the lower limb, finding that while it successfully differentiated between pneumatic and electric sensations at the knee, it failed to do so at the foot, indicating a need to identify external factors before applying the method to amputees.
This study demonstrates that green hydrogen can serve as a stoichiometric electron donor in a cell-free enzymatic system to drive the complete, byproduct-free bioconversion of pyruvate to lactate via efficient NADPH regeneration, offering a scalable platform for reductive biotransformations powered by renewable energy.