📄 chemistry

AQbD-Assisted Development and Validation of a Green RP-HPLC Method for Simultaneous Quantification of Telmisartan, Amlodipine Besylate, and Bisoprolol Fumarate

This study presents a robust, accurate, and environmentally sustainable RP-HPLC method for the simultaneous quantification of Telmisartan, Amlodipine, and Bisoprolol, developed and optimized using an Analytical Quality by Design (AQbD) approach to ensure reliability for routine pharmaceutical quality control.

Paresh Ghughuskar, Ratna Musale, HIRALBEN MEHTA, Prexa Tandel2026-06-24
📄 chemistry

High Performance Epoxy Nanocomposite Linings for Underground Fuel Storage Tanks: Barrier Enhancement and Corrosion Protection

This study demonstrates that incorporating 1 wt% metal vanadium oxyphosphate nanofillers, particularly magnesium-based (Mg-VP), into Bisphenol-F epoxy coatings significantly enhances barrier properties, corrosion resistance, and mechanical performance in chloride environments compared to neat epoxy.

Buthaina S. Aziz, Hisham Anwer Salih, Dalal N. Alhilfi, Abdullah. A. Hussein2026-06-24
📄 chemistry

In doped NiCo-LDH as bifunctional electrocatalysts for overall water splitting

This study reports a facile one-step electrodeposition strategy to synthesize indium-doped NiCo layered double hydroxides on nickel foam, where an optimal 1.0% In doping creates interstitial defects that enhance electronic structure and active sites, resulting in a highly efficient and stable bifunctional electrocatalyst capable of driving overall water splitting at a low cell voltage of 1.73 V.

Zicheng Huang, Mengwei Yu, Yulun Xie, Yuedong Guo2026-06-24
📄 chemistry

Four Decades of Reversed-Flow Gas Chromatography Research (1980–2026): A Bibliometric Analysis, Knowledge Evolution, and Emerging Scientific Frontiers

This study presents a comprehensive bibliometric analysis of 914 Reversed-Flow Gas Chromatography (RF-GC) publications from 1980 to 2026, mapping the field's evolution from fundamental investigations to advanced material applications and identifying future research frontiers in computational integration and data-driven characterization.

Mohammad Hafiz Hamzah, Khalisanni Khalid2026-06-24
📄 chemistry

Reversible covalency reprograms CRBN substrate recruitment and PROTAC-mediated degradation

This study demonstrates that boronic acid-based IMiD derivatives engage the CRBN E3 ligase via reversible covalent coordination with His353, a mechanism that reshapes substrate recruitment and enables the development of highly efficacious PROTACs with sustained degradation capabilities.

Ivan Dikic, Henry Bailey, Thomas Geiger, Serhii Zhersh, Nataliya Tolmachova, Vinay Singh, Ina Dressel, Rubina Kazi, Jona (…)2026-06-24
📄 chemistry

Topology-Driven Photoenhanced Gold Recovery in Three-Dimensional Covalent Organic Frameworks

This study demonstrates that topological engineering in 3D porphyrin-based covalent organic frameworks can significantly enhance photo-driven gold recovery by optimizing charge transport and mass transfer, with an interdigitated lattice structure outperforming its isomer to achieve record-breaking adsorption capacity.

Shuai Fu, Yunyu Guo, Yuan-Zhe Cheng, Jiaqi Guo, Jiahuan Wang, Aowei Lv, Jingyang Lin, Jiaqi Ma, Mischa Bonn, Xuesong Din (…)2026-06-24
📄 chemistry

Concentration and pH Influence on the Radical Scavenging Activity of Black Tea Polyphenols: Implications for pH-Responsive Antioxidant Materials

This study demonstrates that the radical-scavenging activity of Golestan black tea polyphenols is significantly enhanced at lower pH levels and higher concentrations, with DFT analysis confirming their strong electron- and hydrogen-donating capabilities for potential use in pH-responsive antioxidant materials.

Shadi Ghezelbash, Radin Qashghai, Sahel Mesdaghi, Maryam Ferdousi2026-06-24