3598 papers
This retrospective study demonstrates that three monthly intravitreal conbercept injections significantly improve visual acuity, reduce retinal and choroidal thickness, and enhance superficial and deep capillary plexus perfusion in patients with diabetic macular edema.
This study developed a SARIMA(3,0,2)(1,0,1)[52] predictive model using routine weekly data to forecast Lassa fever outbreaks in Ondo State, Nigeria, successfully identifying seasonal peaks between weeks 48 and 52 to guide proactive public health interventions and resource allocation.
This study identifies TMEM45A as an independent poor prognostic biomarker in gastric cancer that drives tumor progression by physically interacting with P4HA1 to elevate succinate levels and activate the TGF-β/Smad signaling pathway.
This study demonstrates that a poloxamer-based intranasal clozapine sol-gel formulation achieves long-term antipsychotic effects in rats at just 4% of the oral therapeutic dose while potentially mitigating gut microbiome disruption associated with oral administration.
This prospective study conducted in a Nepalese tertiary care hospital demonstrates that serum Golgi Protein 73 (GP73) is a highly accurate noninvasive biomarker for distinguishing advanced chronic liver disease and severe fatty liver disease from early-stage fatty liver, outperforming conventional markers like FIB-4 and APRI.
This cross-sectional study analyzing three rounds of Liberia Demographic Health Survey data (2007–2019) reveals a concerning upward trend in unintended pregnancies among reproductive-age women, particularly adolescents, driven by factors such as unmet family planning needs, low modern contraceptive use, and specific demographic characteristics.
This descriptive cross-sectional study of 422 chronic kidney disease patients in Sri Lanka reveals that poor sleep quality and frequent distressing dreams, particularly nightmares, are prevalent and independently associated with higher levels of psychological distress, underscoring the need for routine screening of sleep and dream characteristics in nephrology care within low- and middle-income countries.
This study developed and validated a CatBoost-based machine learning model using nine clinical features to accurately predict preoperative anxiety in elderly hip fracture patients, with SHAP analysis identifying pain levels, age, and comorbidities as key risk factors.
This qualitative study utilizing the Social Ecological Model reveals that malaria persists in Cameroon due to a complex interplay of individual misconceptions, community-level socio-cultural and economic barriers, health system weaknesses, and policy implementation gaps, necessitating multi-sectoral and culturally sensitive interventions for effective control.
This retrospective study of 257 patients found that preoperative tamsulosin administration significantly reduces ureteroscopy failure rates, while flexible ureteroscopy is associated with a higher risk of failure compared to the semi-rigid approach.