13699 papers
This longitudinal cohort study of postmenopausal Chinese women found that persistently poor or worsening self-rated health and increasing mobility limitations between 2011 and 2015 were significantly associated with the subsequent development of newly reported chronic lung disease and asthma by 2018.
This case report describes a 42-year-old woman with a 12-year history of progressive neurological decline and extensive cerebral venous thrombosis, initially misdiagnosed as tuberculous meningitis, who was ultimately treated for possible neurosarcoidosis with corticosteroids and methotrexate, resulting in significant clinical improvement despite the lack of definitive histological confirmation.
This prospective cohort study of Chinese women found that a history of induced abortion, but not spontaneous pregnancy loss, is independently associated with an increased risk of incident asthma, while also revealing that parity and menopausal timing correlate with objective lung function measures despite self-reported COPD diagnoses showing systematic access bias.
This retrospective study of 61 patients found that contour-free complete-series multi-instance learning applied to dual-phase CT scans did not demonstrate a statistically significant discrimination advantage over conventional CT features for preoperative Ki-67 stratification in gastric gastrointestinal stromal tumors.
This study demonstrates that β-sitosterol, a monomer component of *Polygonatum sibiricum*, ameliorates liver fibrosis by inducing apoptosis in LX-2 cells and suppressing fibrosis in CCl4-induced mice through the modulation of the p53/Caspase8/Caspase9/Caspase3 signaling pathway.
This cross-jurisdictional analysis of Canadian public health documents reveals that while provincial and territorial guidance on early childhood caries prevention for parents is largely consistent, the supporting evidence for these recommendations is predominantly of low to very low certainty, highlighting a need for standardized wording and a shared national template to address existing inconsistencies.
This prospective cross-sectional study of 160 cirrhosis patients in Syria demonstrates that hyponatremia (serum sodium ≤130 mEq/L) is significantly associated with greater disease severity, higher frequencies of major complications like hepatic encephalopathy and hepatorenal syndrome, and increased in-hospital mortality.
This cross-sectional study of 565 postmenopausal women in Brazil reveals that higher consumption of ultra-processed foods is positively associated with elevated levels of pro-inflammatory cytokines, whereas greater intake of minimally processed foods correlates with reduced inflammation.
This retrospective multicenter study of 223 heart transplant recipients demonstrates that intraoperative transfusion of apheresis platelets, compared to pooled platelet concentrates, is associated with a significantly lower risk of developing de novo HLA antibodies within one year, suggesting that preferential use of apheresis platelets may reduce alloimmunization and improve long-term outcomes.
This study demonstrates that anthocyanin, a natural pH-sensitive pigment, shows promise as a biocompatible plaque-disclosing agent for detecting cariogenic acidity at highly acidic levels, though its reliability decreases significantly at pH values above 5.0, indicating a need for further optimization before clinical use.