📄 Category

medicine

3605 papers

📄 medicine

Sodium-Glucose Cotransporter-2 Inhibitors and Cutaneous Adverse Reactions: A Systematic Review of Clinical Phenotypes, Time-to- Onset Profiles, and Management Strategies (2020–2026)

This systematic review of 42 studies (2020–2026) characterizes the diverse spectrum of SGLT2 inhibitor-induced cutaneous adverse reactions, distinguishing between early-onset mild eruptions manageable with symptomatic treatment and delayed-onset severe immune-mediated or necrotizing conditions that require drug withdrawal and multidisciplinary intervention.

Yasser Mohammed Abdo Ali Al-Shawki, Ziryab M. Al-Shawki2026-07-15
📄 medicine

Unilateral Internal Carotid Artery Agenesis Incidentally Detected on Trauma CT Angiography: A Case Report and Diagnostic Considerations

This case report describes a 32-year-old man with congenital agenesis of the left internal carotid artery, incidentally identified on trauma CT angiography by the absence of the bony carotid canal, highlighting the critical importance of distinguishing this rare anomaly from acquired occlusion to guide clinical management and future procedural planning.

Deep Parkash, Rani Bai, AlMajd AlYazidi, Moosa Alwadi, Essem Ahmed, Ayman Albatanony, Hosam Elghadban2026-07-15
📄 medicine

Time to Maximal Response of Trastuzumab Deruxtecan in Patients with HER2-Positive Metastatic Breast Cancer: A Multicenter Retrospective Study (TRACE)

In a multicenter retrospective study of 93 patients with HER2-positive metastatic breast cancer, Trastuzumab Deruxtecan achieved maximal tumor shrinkage at a median of 4.57 months, with minimal additional tumor burden reduction observed beyond 18 weeks, suggesting that treatment duration may be optimized by considering this timeframe for induction strategies.

Yukinori Ozaki, Emi Taniguchi, Kazuki Nozawa, Yuka Niwa, Fumikata Hara, Kiyomi Nonogaki, Masahiro Kuno, Yosuke Aoyama, L (…)2026-07-15
📄 medicine

Effects of preference-based workplace active breaks on physical function, muscular strength, and pain

In a pragmatic workplace setting where workers selected their preferred intervention, an 8-week high-intensity strength active-break program yielded superior improvements in physical function and muscular strength compared to a standard stretching program, while both approaches effectively reduced pain-related outcomes.

Iñigo Perez-Garcia, Natalia Burgos Alonso, Ana Belén Fraile-Bermúdez, Idoia Zarrazquin-Arizaga, Amaya Irazusta, Lars Lou (…)2026-07-15
📄 medicine

Development and evaluation of measurement properties of the Sensorimotor Dysfunction Questionnaire for Neuromodulation (SMDQ-n)

This study developed and validated the Sensorimotor Dysfunction Questionnaire for Neuromodulation (SMDQ-n) as a reliable and accurate screening tool for characterizing sensorimotor profiles in patients eligible for non-invasive brain stimulation, demonstrating strong psychometric properties including high internal consistency, structural validity, and excellent criterion validity.

Déborah Marques, Paulo Goes, Andrea Lemos, Katia Monte-Silva2026-07-15
📄 medicine

Can a zero-shot time-series foundation model rival task-trained models for intraoperative hypotension prediction? A two-cohort benchmark and the role of covariate-awareness

This study demonstrates that zero-shot time-series foundation models, particularly TiRex-2, can rival task-trained baselines in predicting intraoperative hypotension across diverse cohorts, offering a portable alternative that maintains high accuracy without requiring site-specific training or drug-infusion covariates.

Max Haberbusch2026-07-15
📄 medicine

Conduction System versus Biventricular Pacing in Pacing-Induced Cardiomyopathy: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis of six observational studies involving 634 patients demonstrates that conduction system pacing (CSP) outperforms biventricular pacing (BVP) as a rescue strategy for pacing-induced cardiomyopathy by yielding superior echocardiographic, electrical, and clinical outcomes, though these findings require validation through randomized trials.

Gregori Yusef Gomez-Duarte, Carlos Manuel Polanco-Ricardo, Melvin De Jesus Acevedo, Juan Isamel Almonte-Gómez2026-07-15
📄 medicine

(STAR-DDI)- STandArdised consensus-based Reporting checklist foR Drug–Drug Interaction checkers and databases

This paper presents the development and validation of the STAR-DDI, a consensus-based 18-item reporting checklist created through a four-round Delphi study to enhance the transparency, consistency, and clinical interpretability of drug–drug interaction checkers and databases.

Brayden Gibson, Catia Marzolini, Saye Khoo, Jack Janetzki, Ingrid Hopper, David FL Liew, Lachlan Dalli, Danijela Gasevic (…)2026-07-15
📄 medicine

Mapping evidence on whole body vibration and lumbar stabilization exercises for postural control in individuals with flexible flatfeet: a scoping review

This scoping review maps existing evidence on whole body vibration and lumbar stabilization exercises for postural control, revealing that while these interventions show promise in related populations, no studies have yet specifically evaluated their effects, individually or combined, in individuals with flexible flatfeet.

Roopa Desai, Sakshi Shah, Manisha Rathi, Tushar Palekar2026-07-15