3605 papers
This retrospective cohort study of 2,459 NSCLC patients identifies that low chemotherapy prescription frequency correlates with poor survival and non-response, while highlighting pre-chemotherapy leukocytosis as a negative prognostic factor and oral receptor tyrosine kinase inhibitors as an effective alternative for non-responders.
This prospective cohort study of 120 Indonesian patients undergoing PCI for STEMI or NSTEMI demonstrates that a high admission systemic immune-inflammation index (SII) independently predicts earlier in-hospital major adverse cardiovascular events, though it does not significantly forecast 30-day post-discharge outcomes.
Supported by the CDC, Zambia's MORE-ZM system transformed fragmented health data management by implementing a centralized DHIS2 ecosystem with automated reporting tools and real-time visualization, significantly reducing reporting times and enhancing data use across 1,584 facilities.
This controlled trial involving amateur runners found that while high-carbohydrate supplementation (80 g/h) did not significantly reduce total marathon finish times compared to a moderate intake (50 g/h), it effectively delayed speed decline and improved pacing stability, particularly in sub-elite athletes, by maintaining glycemic stability during the race.
This mixed-methods observational study demonstrates that the PROMIS GH-10 is a responsive and feasible tool for capturing patient-reported outcomes in Swiss inpatient rehabilitation, showing significant improvements in physical and mental health, though its nationwide implementation requires addressing barriers such as the time needed to assist patients and staff resource constraints.
This study demonstrates that contrast-enhanced 3D MRI detects more spinal hemangioblastomas, particularly small lesions, in von Hippel-Lindau patients compared to 2D imaging, supporting its potential for improved standardized surveillance and longitudinal monitoring despite slightly lower inter-reader agreement.
Drawing on four nationwide surveys in China, this study reveals that while expert trust generally promotes vaccination, science literacy functions as a conditional resource that can paradoxically amplify the negative impact of conspiracy beliefs depending on the specific vaccine context and policy environment.
This paper outlines the protocol for a prospective, multicenter, randomized controlled trial designed to evaluate whether adding endoscopic annular fibrosus repair to standard endoscopic discectomy reduces recurrence rates and improves clinical outcomes for patients with lumbar disc herniation compared to discectomy alone.
This study utilized a co-design process involving diverse stakeholders to develop and validate a practical, evidence-based online toolkit and checklist aimed at empowering primary care dietitians to deliver optimized, consistent nutrition care for cancer survivors.
This case report describes the rare and fatal progression of infectious shock caused by an Escherichia coli-induced ruptured pyometra in a 60-year-old postmenopausal woman, highlighting the critical need for early recognition and aggressive management of this life-threatening condition.