7905 papers
This prospective single-center study of 155 children demonstrates that ultrasound-derived fat fraction (UDFF) is strongly correlated with MRI-PDFF and exhibits high apparent diagnostic accuracy for detecting hepatic steatosis, though the identified cutoff values require external validation before clinical use.
A single dose of the Chikungunya virus-like particle vaccine (VIMKUNYA) demonstrates a favorable safety profile and induces rapid, robust, and durable neutralizing antibody responses across a broad age range of 12 to 95 years, supporting its suitability for public health implementation.
This study demonstrates that deep learning models, particularly EfficientNet-B1, achieve high diagnostic accuracy in detecting lung cancer from white light bronchoscopic images, suggesting their potential as a valuable clinical adjunct despite modest performance in histologic subtype classification.
This cross-sectional analysis of the 2023–2024 National Survey of Children's Health reveals that among U.S. children and adolescents with current asthma, meeting more components of the 24-hour movement guidelines (physical activity, limited screen time, and adequate sleep) is significantly associated with a higher prevalence of caregiver-reported flourishing, although this relationship is not unique to children with asthma.
Although HIV testing coverage among children under 15 in South Africa significantly increased from 36.8% in 2017 to 41.5% in 2022, it remains inadequate with persistent disparities linked to age, rural residence, and healthcare access, necessitating targeted, child-centered interventions to close the testing gap.
This modeling study projects that implementing mandatory front-of-package labeling policies in the United States, particularly traffic light and warning label systems, would significantly reduce obesity prevalence and avert hundreds of thousands of premature deaths through 2043.
This study reveals that prostate cancer screening uptake is virtually non-existent among male teachers in Obudu LGA, Nigeria, due to overwhelmingly poor knowledge, negative attitudes, and perceptions, despite their educational status.
This study utilized 3D flow simulations on chicken sciatic artery biopreparates to demonstrate that end-to-side vascular anastomoses performed at 30° and 45° angles offer the most optimal hemodynamic conditions, balancing wall shear stress and flow stability compared to other tested angles.
This comparative study demonstrates that digital intraoral periapical radiography provides linear and angular measurements of intrabony periodontal defects with accuracy and agreement comparable to cone-beam computed tomography, supporting its use as a cost-effective, lower-radiation alternative for routine assessments while reserving CBCT for complex three-dimensional evaluations.
This study identifies a novel D-2-hydroxyglutarate inhibitor through *in silico* screening and validates its significant therapeutic efficacy in reducing tumor growth and oncometabolite levels in a preclinical glioblastoma rat model.