📄 medicine

Endoscopic Discectomy with Repair of Annulus Fibrosus versus Discectomy Alone for Lumbar Disc Herniation: Study protocol for a Prospective Multicenter Randomized Controlled Trial

This paper outlines the protocol for a prospective, multicenter, randomized controlled trial designed to evaluate whether adding endoscopic annular fibrosus repair to standard endoscopic discectomy reduces recurrence rates and improves clinical outcomes for patients with lumbar disc herniation compared to discectomy alone.

Panchen Zhao, Wenhao Zhao, Haixin Wei, Hao Zhang, Hao Tao, Xuexiao Ma2026-07-15
📄 medicine

When alpha-gal hides: A case series of atypical presentations of alpha-gal syndrome in children

This case series highlights four pediatric patients with atypical presentations of alpha-gal syndrome, such as respiratory distress, gastrointestinal issues, and chronic urticaria, demonstrating that the condition can be misdiagnosed without a high index of suspicion for tick-bite sensitization despite the absence of classic immediate food reactions.

Tharindi Suriapperuma, Nadisha Badanasinghe, Sachith Mettananda2026-07-15
📄 medicine

CGRP Receptor Antagonism with Rimegepant as an Acute Intervention for repeated idiopathic sudden sensorineural hearing loss : A Case Report

This case report demonstrates that a single daily dose of the CGRP receptor antagonist rimegepant effectively restored hearing and resolved symptoms in a 27-year-old woman with recurrent idiopathic sudden sensorineural hearing loss and a history of migraine, supporting the concept of cochlear migraine and the potential of CGRP-targeted therapy.

Luo Yunfan, Chen Liqing, Zhang Xiaoyan, Hao Yuelin, Diao Tongxiang, Zhang Nannan, Zhang Qingfeng, Yuan Qing2026-07-15
📄 medicine

Adult-Onset Still’s Disease – Still a Diagnostic Dilemma: A Case Report

This case report describes a 31-year-old male with extreme hyperferritinemia and fever of unknown origin who was successfully diagnosed with Adult-Onset Still's Disease and treated with corticosteroids followed by Tocilizumab, underscoring the critical importance of early recognition and targeted therapy to prevent severe complications like macrophage activation syndrome.

SYED SIKANDAR SHAH, Assadullah Dahani, Aftab Alam, Hadeel Eyad Abdel latief Shalabi, Jamil Ahmed, Nour Aymn Ahmad, Marya (…)2026-07-15