📄 medicine

Time to Death and its Predictors among Stroke Patients with Hypertension at Comprehensive Specialized Public Hospitals

This retrospective cohort study of 737 hypertensive stroke patients in Ethiopia's Amhara region found a median time to death of 40 days, identifying advanced age, elevated blood pressure, alcohol consumption, low Glasgow Coma Scale scores, admission complications, and hemorrhagic stroke as significant predictors of mortality, while cardiovascular disease appeared to be a protective factor.

Yihenew Sewale Bizu, Kassahun Dires Ayenew2026-10-18
📄 medicine

Effect of mouth breathing on condylar position in children: A CBCT retrospective study

This retrospective CBCT study of 244 children aged 7–12 found that mouth breathing significantly alters condylar position, causing a more posterior, superior, and medial displacement with increased bilateral asymmetry compared to nasal breathing, thereby highlighting the need for early orthodontic monitoring to prevent temporomandibular joint dysfunction.

Jian Wang, Ran Chen, Tao Qiu, Jin Zhao, Xiangtao Liu, Xiao Zhu, Junzhuo Gou, Yafen Zhu, Zhifang Wu2026-10-18
📄 medicine

Predictors of Prolonged Survival in Tokuhashi Group 1 Patients After Surgery for Metastatic Spinal Cord Compression

This retrospective cohort study of 367 Tokuhashi Group 1 patients undergoing surgery for metastatic spinal cord compression identifies kidney, prostate, and breast primary tumors as robust independent predictors of postoperative survival exceeding six months, suggesting that modern systemic therapy responsiveness should inform surgical candidacy despite low prognostic scores.

Jae-Won Shin, Phil-Sun Park, Dong-Ki Kim, Chan-Woo Kim, Hak-Sun Kim, Seong-Hwan Moon, Kyung-Soo Suk, Byung-Ho Lee, Ji-Wo (…)2026-10-18
📄 medicine

Laparoscopy-first Hartmann strategy for generalized diverticular peritonitis: a national multicenter overlap-weighted cohort study

In a national multicenter cohort study of patients with generalized diverticular peritonitis, a laparoscopy-first Hartmann strategy failed to improve early postoperative outcomes and resulted in significantly lower stoma reversal rates at 12 months compared to protected resection-anastomosis, supporting the latter as the preferred approach when technically feasible.

Thomas Husson, Arnaud Alves, Laura Beyer-Berjot, Mehdi Ouaissi, Valérie Bridoux, Mehdi Karoui, Charles Sabbagh, Antoine (…)2026-10-18
📄 medicine

Evaluation Of Blood Platelet Indices, Platelet Aggregation And Coagulation Profile In The Activity State Of Inflammatory Bowel Disease Patients On Biological Treatment

This study demonstrates that altered platelet indices, specifically elevated PLR and NLR alongside reduced MPV, and increased platelet aggregation serve as effective non-invasive biomarkers for monitoring inflammatory bowel disease activity and response to biological therapy.

Mohammed Zain, Maria Hamdy, Safinaz Hussin2026-10-18
📄 medicine

Cognitive Impairment during Migraine Attacks: An Analysis from the American Registry for Migraine Research (ARMR)

In a large cohort from the American Registry for Migraine Research, subjective cognitive impairment during migraine attacks was found to be nearly universal and more strongly predicted by anxiety, depression, sensory sensitization, and full-cycle symptoms than by migraine frequency alone.

Meesha Trivedi, Richa Chirravuri, Todd J. Schwedt, Ryotaro Ischii, Gina Dumkrieger, David Dodick, Christopher H. Gottsch (…)2026-10-18
📄 medicine

Machine Learning and Large Language Models for Maternal Cardiometabolic Risk Prediction Across Harmonised Public Pregnancy Datasets

This study developed an integrated framework for maternal cardiometabolic risk prediction using harmonised public datasets, revealing that while conventional machine learning models achieved strong internal performance, they generalised poorly across datasets, whereas large language models demonstrated moderate risk assessment capabilities and the ability to generate clinically relevant explanations.

Shaoxun Wen, Yaqun Tang, Binning Ma, Bin Cao, Zhenxing Deng2026-10-18
📄 medicine

Association of daily and on-demand tadalafil use with all-cause mortality and cardiovascular outcomes in men with erectile dysfunction and lower urinary tract symptoms: a propensity score-matched real-world cohort study

This propensity score-matched cohort study found that while both daily (5 mg) and on-demand (20 mg) tadalafil use were associated with significantly lower risks of all-cause mortality and cardiovascular events compared to non-use in men with erectile dysfunction or lower urinary tract symptoms, on-demand tadalafil 20 mg was linked to superior long-term survival outcomes compared to the daily regimen.

Yeow Siong Lee, Chuan-Shu Chen, Gu-Shun Lai, Jian-Yi Li2026-10-18
📄 medicine

Spontaneous Coronary Artery Dissection Presenting with Monomorphic Ventricular Tachycardia in a Young Man Hospitalized for Pneumonia and Severe Coughing Episodes: A Case Report

This case report describes a rare instance of spontaneous coronary artery dissection (SCAD) in a young man, triggered by severe coughing during a pneumonia hospitalization, which presented as monomorphic ventricular tachycardia and inferior ST-elevation myocardial infarction, ultimately managed successfully with conservative therapy.

Alihan Ersin, Metin Açar, Mehmet Engin Berk, Mustafa Uçar, Ferhat Özyurtlu, Nurullah Çetin2026-10-18