📄 Category

medicine

13757 papers

📄 medicine

Perioperative Hemodynamic Management in Elderly Hypertensive Patients: A Systematic Review of Monitoring-Guided Strategies and Postoperative Outcomes

This systematic review of 19 studies involving over one million elderly hypertensive patients undergoing non-cardiac surgery finds that while intraoperative hypotension is consistently associated with organ injury in observational data, randomized evidence does not support the routine use of higher blood pressure targets, goal-directed hemodynamic therapy, or specific antihypertensive withholding strategies to improve postoperative outcomes in this population.

Marva Ashiq, Weiwei Zhang, Lianyu Li2026-10-18
📄 medicine

Gold Nanoparticle-Loaded Biodegradable Polyanhydride Wafers Provide Sustained Gold Availability and Enhance Radiosensitization of Glioblastoma Cells

This study demonstrates that biodegradable P(CPP:SA) wafers loaded with gold nanoparticles provide sustained local gold availability and significantly enhance radiosensitization in glioblastoma cells compared to free nanoparticles, establishing a promising in vitro proof of concept for localized post-surgical therapy.

Di Zhang, Tianzhu Wang, Tianqi Yi, Tong Chen2026-10-18
📄 medicine

Intrathecal Baclofen Trial as a Predictor of Long-Term Outcomes After Selective Dorsal Rhizotomy in Children with Spastic Cerebral Palsy

This study demonstrates that short-term clinical improvements observed during an intrathecal baclofen trial generally approximate long-term functional outcomes following selective dorsal rhizotomy in children with spastic cerebral palsy, suggesting the trial is a valuable tool for patient selection and expectation setting.

Antonio Malaspina, Hannah Weiss, Patricia Siegel, Sebastián N. Anderson, Spencer Frome, Owen Les, Daniela I. Anderson, B (…)2026-10-18
📄 medicine

One-year clinical outcome after combined cataract surgery with excimer laser trabeculostomy versus cataract surgery alone in open-angle glaucoma: real life data in a community-based outpatient setting

In a community-based outpatient setting, combined cataract surgery with excimer laser trabeculostomy demonstrated a statistically significant reduction in intraocular pressure and topical medication usage at 12 months compared to cataract surgery alone in patients with open-angle glaucoma.

Fidan A. Aghayeva, Abdelrahman Assaf, Shen Li, Ines Lanzl2026-10-18
📄 medicine

Efficacy and Facial Microbiome Modulation of 30% Supramolecular Salicylic Acid versus Topical Fusidic Acid in Mild-to-Moderate Acne Vulgaris: A Randomized Comparative Study

In a randomized comparative study of 46 patients with mild-to-moderate acne, 30% supramolecular salicylic acid peeling demonstrated clinical efficacy comparable to topical fusidic acid over eight weeks, with neither treatment showing a distinct advantage in modulating the skin microbiome or avoiding antimicrobial resistance concerns.

Jinghan Yuan, Yutong Xie, Can Cui, Ruojun Wang, Aihua Wei, Rong Tao2026-10-18
📄 medicine

A hidden signal in the resting hand: dissociable bilateral activation after stroke

This study demonstrates that covert bilateral activation in the resting hand after stroke is not a uniform overflow signal but comprises dissociable features—coupling rate and intensity—that differentially reflect movement constraints in paretic patients and disrupted action representation in apraxia-dominant patients, as revealed by high-density electromyography.

Rossana Lovecchio, Pranav Mamidanna, Nga Man Ting, Pasquale Ferrentino, Felicia Tassone, Vishal Rawji, Matthew Banger, A (…)2026-10-18