📄 Category

medicine

3708 papers

📄 medicine

Development and Internal Validation of a Nomogram for Predicting 28-Day Mortality in Elderly Hip Fracture Patients Admitted to the Intensive Care Unit: A Retrospective Cohort Study Based on MIMIC-IV

This retrospective cohort study utilizing the MIMIC-IV database developed and internally validated a nomogram incorporating initial hyperlactatemia, age, blood urea nitrogen, and the paradoxical protective effect of diabetes to predict 28-day mortality in elderly hip fracture patients admitted to the ICU.

Yifeng Zhao, Jinxuan Li, Xiaoping Cui2026-07-14
📄 medicine

Integrating value-based reflection into the 7E teaching model in nursing rounds: Effects on nursing students’empathy, moral sensitivity, humanistic care, and patient safety—A quasi-experimental study

This quasi-experimental study demonstrates that integrating value-based reflection into the 7E teaching model for nursing rounds significantly enhances nursing students' empathy, moral sensitivity, humanistic care, and patient safety competence compared to traditional instruction.

Na Zhang, Xue Zhang, Chenlin Yu, Hanyu Li, Shaoli Zhang, Junfan Zhou, Minling Mo2026-07-14
📄 medicine

Diagnostic Performance of Clinical, Biochemical and Ultrasonographic Parameters in Differentiating Biliary Atresia from Idiopathic Neonatal Hepatitis: A Prospective Study from a Tertiary Care Center of Nepal

This prospective study from a Nepalese tertiary center demonstrates that a cost-effective diagnostic strategy combining persistent acholic stool, a serum GGT cutoff of ≥384.5 U/L, and ultrasonography can effectively differentiate biliary atresia from idiopathic neonatal hepatitis, offering a high-sensitivity parallel screening approach followed by a high-specificity serial confirmation for resource-limited settings.

Saroj Kumar Sah, Raj Kumar Nepal, Sumit Agrawal, Santosh Adhikari, Lisha Yadav, Baburam Pandey, Ram Hari Chapagain2026-07-14
📄 medicine

Development and validation of a 17-year risk prediction nomogram for metabolic syndrome: a retrospective cohort study

This retrospective cohort study developed and validated a robust 17-year risk prediction nomogram for metabolic syndrome using 11 key clinical factors, demonstrating high accuracy and clinical utility for early identification and intervention in a large population-based sample.

Lei Yu, Kexin Zhao, Zhendong Hu, Weihong Zhou, Minhua Luo, Pengfei Zhang, Tiancheng Xu2026-07-14
📄 medicine

Dynamic Patterns of Estimated Cardiorespiratory Fitness and Risk of Depressive Symptoms in Older Adults: A Longitudinal Analysis Using LTMLE

Using longitudinal data from 7,109 older adults and advanced causal inference methods, this study demonstrates that maintaining high estimated cardiorespiratory fitness over time significantly and independently reduces the risk of depressive symptoms, whereas rapid declines in fitness eliminate these protective benefits.

Jingyi Li, Yaning Feng2026-07-14
📄 medicine

Burnout Syndrome, sleep quality and the effect of the practice of physical activities among community pharmacists in Douala, Cameroon: A Cross-Sectional Study

This cross-sectional study of 136 community pharmacists in Douala, Cameroon, reveals a high burnout prevalence of 65.4% that is significantly associated with annual holidays and other activities, while showing no overall link between burnout and physical activity or sleep quality, though moderate physical activity was specifically linked to a higher risk of depersonalization.

Léon Jules Owona Manga, Jerson Mekoulou Ndongo, William Mbang Bian, Elysée Claude Bika Lele, Estelle Marcelle Fleurie Ng (…)2026-07-14
📄 medicine

Australian Health Professionals’ Understandings and Experiences of Broad Consent for the Future Research Use of Paediatric Genomic Data

This qualitative study of Australian health professionals reveals that broad consent for future paediatric genomic research is ethically defensible and supported when accompanied by clear explanations, robust safeguards, voluntary participation, and practices that progressively involve children as their decision-making capacity develops.

Yingyi Luo, Louise Keogh, Bernadette Richards, Monica Ferrie, Jane Nielsen2026-07-14
📄 medicine

Anticoagulation versus Antiplatelet Therapy After Cancer-Associated Ischemic Stroke: A Net-Benefit Threshold Analysis

This study uses a net-benefit threshold model to demonstrate that current randomized evidence fails to show anticoagulation provides a sufficient reduction in recurrent stroke to outweigh bleeding risks compared to antiplatelet therapy for cancer-associated ischemic stroke, thereby supporting the need for a confirmatory trial rather than a change in clinical practice.

Hyun Dong Yoo, Jae Guk Kim, Seung Young Chung2026-07-14
📄 medicine

Real-World Outcomes of Tyrosine Kinase Inhibitors in Radioactive Iodine-Refractory Differentiated Thyroid Cancer: A Cohort Study with Focus on Neoadjuvant Use

This retrospective cohort study of 35 Colombian patients with radioactive iodine-refractory differentiated thyroid cancer demonstrates that tyrosine kinase inhibitors, particularly lenvatinib, provide meaningful disease control and enable surgical resection in the neoadjuvant setting within a real-world clinical practice.

Santiago Orozco-Montoya, Guillermo Salazar-Villa, Wilfredo A. Rivera-Martínez, Carlos E. Builes-Montaño, Alejandro Román (…)2026-07-14