📄 medicine

Right Vertical Infra-Axillary Minithoracotomy Versus Median Sternotomy for Doubly Committed Subarterial Ventricular Septal Defect: A Retrospective Cohort Study of 689 Patients

This retrospective cohort study of 689 patients demonstrates that right vertical infra-axillary minithoracotomy is a safe and feasible alternative to median sternotomy for repairing doubly committed subarterial ventricular septal defects, offering comparable perioperative safety and clinical outcomes while significantly reducing hospital stay, mechanical ventilation duration, and improving incision-related satisfaction.

Xinyi Li, Wenjie Bao, Dawei Jin, Yanlong Wang, Jiameng Zhu, Jingyun Shi, Tianqi Li, Yanjun Pan, Meng Yin2026-10-18
📄 medicine

Advanced Technology Intraocular Lens Utilization in Eyes with Glaucoma and Diabetic Retinopathy Across US Academic Centers: Analysis of the SOURCE Repository

This multicenter retrospective study of over 250,000 cataract surgeries across US academic centers reveals that while advanced technology intraocular lens (ATIOL) utilization has increased significantly since 2009, it remains substantially lower for patients with glaucoma or diabetic retinopathy—particularly as disease severity increases—and is marked by persistent disparities based on language and race.

Raena Greenbaum, Baokun Gu, Jee-Young Moon, Neelima Dosakayala, Olivia Allen, Jeffrey Schultz, Anurag Shrivastava2026-10-18
📄 medicine

Application of Bioimpedance in Community Screening and Early Detection of Oral Potentially Malignant Disorders

This prospective study demonstrates that multi-frequency bioimpedance spectroscopy is a rapid, non-invasive, and reliable tool for differentiating oral potentially malignant disorders and dysplastic tissues from healthy mucosa, offering significant potential for community-based early detection of oral squamous cell carcinoma.

Rashtwar Kaushiki, Hande Alka, Sonone Archana, Patil Swati, Pakhale Aayushi2026-10-18
📄 medicine

Predictive Value of EuroSCORE II in Contemporary Cardiac Surgery : Insights from the EPICARD Registry

This study of 108,412 patients in the French EPICARD registry confirms that EuroSCORE II maintains good discriminative ability for operative mortality in contemporary cardiac surgery but exhibits calibration limitations in high-risk subgroups, highlighting the need for periodic model updates.

Juliette PICCOLI, Maelle Youinou, Jean-Christian Roussel, Pascal Leprince, Jean-Philippe Verhoye, Christophe Baufreton (…)2026-10-18
📄 medicine

Depressive status modulates hippocampal-cortical dynamics during acute nicotine use

This study demonstrates that depressive status modulates hippocampal-cortical dynamics during acute nicotine use, revealing distinct neural responses to mood and craving in depressed versus non-depressed individuals while highlighting the potential for personalized treatment approaches based on neurophysiological subtypes.

Jihye Ryu, Lisette Torres, Michael Ward, Uros Topalovic, Mauricio Vallejo Martelo, Humza Zubair, Ausaf Bari2026-10-18
📄 medicine

Antiseizure Medication Use and Multidimensional Biological Aging: A UK Biobank Study

A UK Biobank cross-sectional study of over 320,000 participants found that antiseizure medication use is associated with accelerated multidimensional biological aging across multiple physiological and molecular indicators, though the cross-sectional design precludes causal conclusions.

Jiayi Xing#, Siqi Ding, Zixian Zhou#, Yiqian Li, Yuqian Li, Yuchen Xu, Jiaxin Li, Yuxi Zhang, Yifei Chen, Minghao Li, An (…)2026-10-18
📄 medicine

Beyond the  Paralyzed Arm: Quantifying  Intentional Motor Control Capacity in People with Severe  Arm Impairment Post-Stroke with High-Density Surface EMG

This study demonstrates that high-density surface EMG can reveal hidden, graded intentional motor control capacity in half of stroke patients with clinically severe arm paralysis (ARAT ≤ 10), identifying a subset of individuals who, despite appearing non-functional on standard scales, retain the voluntary drive necessary for intention-based rehabilitation.

Keren Pollack, Noy Goldhamer, Adi Lorber Haddad, Gil Meir, Hadar Idan, Tamar Mizrahi, Lior Shmuelof2026-10-18
📄 medicine

Impact of enhanced malaria surveillance processes and data feedback on data comprehensiveness and malaria case management in Arba Minch Zuriya District, Ethiopia: a pre-post implementation study

This pre-post implementation study in southern Ethiopia demonstrates that integrating enhanced malaria surveillance with a Continuous Quality Improvement (CQI) program significantly improved data completeness, adherence to recommended antimalarial treatments, and the accuracy of weight-based drug dosing across two public health centers.

Tamiru Shibiru Degaga, Samuel Alemu Bamboro, Tedla Teferi Tego, Kalkidan Muluneh Mengistu, Hellen Mnjala, Grant Lee, Rob (…)2026-10-18
📄 medicine

“They’re from another planet”: a reality check on the relational architecture of surgical site infection prevention — qualitative exploration for a social network analysis

This qualitative study of five Swiss-German hospitals reveals that effective surgical site infection prevention relies less on formal protocols and more on the quality of everyday interpersonal relationships, trust, and communication between surgical and infection control teams, which often determine whether guidelines are successfully translated into local practice.

Kavitha Vallonthaiel, Ulrik Brandes, Hugo Sax2026-10-18
📄 medicine

Traumatic subdural and subarachnoid hemorrhage following misuse of an inflatable bouncer in an infant: a case report and injury alert

This case report describes a rare instance of severe traumatic intracranial hemorrhage in a 13-month-old infant caused by the misuse of an inflatable bouncer, underscoring the critical need for strict adherence to age restrictions and enhanced safety awareness for such playground equipment.

Yuki Kimua-Iai, Mikio Kato, Shuichi Shimakawa, Yutaka Odanaka, Hikaru Tsuda-Kitahara, Miho Fukui, Kanta Kishi, Akira Ash (…)2026-10-18