📄 Category

medicine

3708 papers

📄 medicine

Five-Year Outcomes of UKA Versus TKA in Elderly Patients With Severe Varus Deformity in Knee Osteoarthritis: The Modifying Effect of Preoperative Extensor Muscle Radiomics Quality

In elderly patients with severe varus knee osteoarthritis, unicompartmental knee arthroplasty (UKA) demonstrates comparable five-year clinical outcomes to total knee arthroplasty (TKA) with reduced surgical trauma and faster early recovery, although the early functional advantage of UKA is attenuated in patients with poorer preoperative extensor muscle quality as quantified by radiomics.

Xianyi Zhang, Jie Shang, Peijia Su, Guizhu Ji, Ziwei Xia, Youdi Xue, Hengcai Zhou, Meng Han, Chao Ma2026-07-14
📄 medicine

Radiographic phenotypes of spinal deformity in osteogenesis imperfecta: a latent class analysis

This study utilized latent class analysis on radiographic data from 62 patients with osteogenesis imperfecta to identify two distinct spinal deformity phenotypes (severe and moderate), suggesting that this probabilistic classification approach could enhance prognostic assessment and guide individualized treatment strategies.

Marcos Vaz de Lima, João Vítor da Silva Fonseca, Bruna Vasconcellos Affonso, Arthur Moretti Gonçalves, Miguel Akkari, Cl (…)2026-07-14
📄 medicine

Application of Multifeature EEG Analysis and Machine Learning in the Investigation of Neurobiological Mechanisms of Schizophrenia

This study proposes a Genetic Algorithm-based Voting ensemble learning model (GA-Voting) that integrates power spectral density, fuzzy entropy, and phase lag index features from resting-state EEG data to achieve highly accurate (99.55%) diagnosis of schizophrenia while offering new insights into its underlying neurobiological mechanisms.

Xin’e Xie, Xiaosong Cao, Shouqing Liu, Dandan Zhao, Xiyuan Mu, Fangqing Zhu, Xiaodong Luo, wanxiu xu, Yunqi Zhu, Yongwei (…)2026-07-14
📄 medicine

Scaling Village Health Leader–Led Community Maternal and Newborn Health Interventions in Underserved Ethiopian Communities: Evidence on Effectiveness, Safety, and Implementation

This study demonstrates that scaling up Village Health Leader–led community interventions in underserved Ethiopian agrarian and pastoralist settings is a feasible, safe, and effective strategy that significantly improves maternal and newborn health outcomes, including increased facility deliveries, reduced postpartum hemorrhage, and higher uptake of essential commodities like misoprostol and family planning.

Gizachew Tadele Tiruneh, Agumasie Semahegn, Nebreed Fesseha, Mesele Damte Argaw, Hillina Tadesse, Tamar Chitashvili, Ale (…)2026-07-14
📄 medicine

Adipose-derived mesenchymal stem cell-derived exosomal miR-22-3p alleviates depression-like behaviors via the FURIN/HMGB1 axis

This study demonstrates that intranasal administration of adipose-derived mesenchymal stem cell-derived exosomes engineered to deliver miR-22-3p alleviates depression-like behaviors in a rat model by inhibiting the FURIN/HMGB1 axis, thereby reducing neuroinflammation and neuronal apoptosis.

Yuxin Xu, Yanqiu You, Dekai Wei, Rong Liang, Weiping Liang, Bingzheng Feng, Jibing Chen, Jia Liang, Fujun Li2026-07-14
📄 medicine

Validation of non-stent criteria post-endoscopic stone management. Contemporary study

This contemporary study validates Hekal's "5-Not's" criteria as a reliable, high-specificity framework for identifying ideal candidates for stentless endoscopic urinary stone management, demonstrating that while the criteria effectively confirm suitability for stent-free recovery, they should not be used as an exclusive screening tool to rule out patients who fail to meet all five conditions.

Ihab A. Hekal, Jana Hekal, Yousef Hekal2026-07-14
📄 medicine

Psychometric Properties of the Spanish version of the Detail and Flexibility Questionnaire (DFlex)

This study validates a reliable and effective 10-item Spanish brief version of the Detail and Flexibility Questionnaire (DFlex) for assessing cognitive rigidity and attention to detail in individuals with eating disorders and the general population.

Javier Manchón López, Álvaro Ruiz-Maciá, Ricardo Sanmartin López, Sofía Payá-López, Katina Ilieva Kovacheva, Eva Mª León (…)2026-07-14
📄 medicine

Association of pulmonary function test patterns with clinical features and laboratory findings in patients with sarcoidosis: a multicenter observational study

This multicenter observational study of 590 sarcoidosis patients reveals that those presenting with restrictive pulmonary function patterns at diagnosis exhibit more advanced radiological stages, lower DLCO values, and higher treatment needs compared to those with normal or obstructive patterns, suggesting a more severe disease course requiring closer monitoring.

Selma Aydogan Eroglu, Omur Gungor, Murat Kavas, Dildar Duman, Fatma Demirci Ucsular, Gulistan Karadeniz, Nurgul Bozkurt (…)2026-07-14
📄 medicine

Multidimensional Determinants of Childhood Wasting among Children Under Five in West Africa

This study utilizes Beta Generalized Linear Mixed Models and Random Forest algorithms on World Bank data to identify agricultural water withdrawal and access to basic drinking water as the most critical, consistent determinants of childhood wasting in West Africa, recommending targeted water management and infrastructure improvements to mitigate the issue.

George Fosu Nimako, Adusei Bofa, Priscilla Felicia Tano, Christa Osei-Mensah, Georgina Afoakwah2026-07-14