13757 papers
In a cohort of Japanese patients with type 2 diabetes and biopsy-proven MASLD, the GLP1R rs10305420 T-allele was associated with lower BMI and more severe liver inflammation and fibrosis, though it did not predict differential hepatic treatment responses over 12 months.
This qualitative meta-synthesis of 13 studies reveals that cervical cancer patients face complex, multidimensional symptom burdens and coping challenges, highlighting the urgent need for early symptom recognition, integrated multidimensional care, and robust multilevel support systems to improve patient-centered management.
This study establishes a methodological framework for pandemic preparedness by demonstrating that early point-of-care biomarkers, specifically high levels of LDH or IL-6, can accurately predict COVID-19 hospitalization risk and disease severity in non-vaccinated individuals, outperforming traditional demographic factors like age and BMI.
This single-center retrospective cohort study developed and temporally validated a logistic regression model using seven clinical predictors to accurately stratify the risk of emergence agitation in older patients undergoing orthopedic surgery under general anesthesia, demonstrating strong discrimination performance that warrants further multicenter external validation.
This paper reports the first MRA-diagnosed case of a congenital arterial ring formed by an anastomosis between an extracranial C1/2-origin left PICA and the V4 segment of the left vertebral artery, highlighting its potential role as a critical collateral pathway in cerebrovascular disease.
This study reveals that peripheral artery disease is characterized by systemic myeloid immune remodelling, specifically involving neutrophil priming with enhanced inflammatory cytokine production but impaired phagocytic and oxidative functions, alongside monocyte dysfunction marked by attenuated cytokine responses despite increased cell counts.
This qualitative study of 19 Turkish radiologists reveals that artificial intelligence is primarily perceived as a supportive strategic partner that enhances professional autonomy and decision-making rather than a threat to medical authority, though its successful integration requires improved AI literacy and clear legal frameworks to address liability and ethical concerns.
This study utilizing the MIMIC-IV database demonstrates that an elevated preoperative glucose-to-albumin ratio is independently and linearly associated with increased risk and severity of postoperative acute kidney injury in cardiac surgery patients, and that interpretable machine learning models incorporating this biomarker achieve excellent predictive performance.
This retrospective cohort study of 203 septic shock patients found that while early-onset sepsis-associated acute kidney injury (within 48 hours) is more common and requires continuous renal replacement therapy more frequently than late-onset cases, the timing of injury does not significantly impact 28-day mortality or long-term kidney outcomes.
This case report describes a rare instance of *Mycoplasma hominis* bloodstream infection in a patient undergoing transfemoral cannulation for extracorporeal life support, highlighting the need to consider this atypical pathogen in catheter-related infections near the urogenital tract.