📄 Category

medicine

13769 papers

📄 medicine

Cross-cultural adaptation of the University of Canberra Fast Jet Aircrew Musculoskeletal Questionnaire (UC-FJAMQ) for musculoskeletal complaint surveillance in Brazilian Air Force pilots

This study successfully performed the cross-cultural adaptation and validation of the University of Canberra Fast Jet Aircrew Musculoskeletal Questionnaire (UC-FJAMQ) for the Brazilian Air Force, resulting in a reliable, expert-validated instrument for monitoring musculoskeletal complaints across diverse military aviation operations.

Thaís de Albuquerque, Jose Roberto Andrade Nascimento Júnior, Guilherme Eugênio van Keulen, Helder Guerra de Resende, Pe (…)2026-10-16
📄 medicine

Exploring the developmental impact of internalising problems on hyperactivity/inattention symptoms in adolescence: An analysis of two UK-based longitudinal studies

Using data from two large UK longitudinal studies, this research demonstrates that internalising problems significantly exacerbate hyperactivity/inattention symptoms during adolescence, challenging the traditional view that hyperactivity/inattention is the primary causal driver of this co-occurring relationship.

Aja Louise Murray, Xinxin Zhu, Xuefei Li, Zhuoni Xiao, Yi Yang2026-10-16
📄 medicine

Pupillometric Markers of Locus Coeruleus–Norepinephrine Activity Are Associated with Internalizing Psychopathology in Adolescents

This study demonstrates that in adolescents, larger baseline pupil size (indicating heightened locus coeruleus–norepinephrine tonic activity) interacts with cortisol levels to predict internalizing psychopathology, suggesting that autonomic arousal markers offer distinct and complementary insights into stress-related mental health beyond traditional endocrine measures.

Nico Bast, Anna Katharina Müller, Christina Luckhardt, Sophia Herlitz, Anka Bernhard, Christine Margarete Freitag2026-10-16
📄 medicine

Impact of Thalidomide Addition on Health-Related Quality of Life in Transfusion-Dependent Thalassemia Patients: A Prospective Study

This prospective study conducted at Peshawar Institute of Medical Sciences demonstrates that adding thalidomide to standard therapy for transfusion-dependent thalassemia patients significantly improves health-related quality of life across all SF-36 domains while increasing hemoglobin levels and reducing transfusion requirements after six months of treatment.

Tariq Hamayun, Majid Ullah, Noor Ul Haram Khattak, Anam Zaman, Arooj Khan, Faizan Sadiq, Abdur Rehman, Muhammad Isa, Ami (…)2026-10-16
📄 medicine

Systemic Immune Reprogramming After Tumor Resection: Perioperative Changes in Chemokines and Immune Checkpoint Markers in Oral Squamous Cell Carcinoma

This study demonstrates that oral squamous cell carcinoma drives coordinated systemic immune activation characterized by elevated chemokines and immune checkpoint markers, which rapidly normalize within the first week following tumor resection, suggesting the potential of perioperative immune dynamics and composite signatures as non-invasive tools for disease detection and monitoring.

Miriam Kokal-Ribaudo, Niclas Rénevier, Juliana Sufcak, Xiangyuan Wu, Ole Moritz Block, Katharina Besch, Christina Bäcker (…)2026-10-16
📄 medicine

Intentional External Scaffolding and Friction as a Novel Non-Pharmacological Behavioral Framework for Executive Dysfunction and Metabolic Health in Late-Diagnosed Neurodivergent Adults

This paper presents a novel theoretical framework and clinical protocol called the Strength Protocol Program, which utilizes intentional external scaffolding and friction to address executive dysfunction and metabolic health in late-diagnosed neurodivergent adults with obesity, though it currently offers only a theoretical description without reported efficacy data.

Dylan Kratochvil2026-10-16
📄 medicine

Mediating role of the Dietary Index for Gut Microbiota in the association between depression and cardiovascular health among US adults

Using data from 18,071 US adults, this study demonstrates that depressive symptoms are negatively associated with cardiovascular health (Life's Essential 8) and that the Dietary Index for Gut Microbiota partially mediates this relationship, particularly among women and individuals with gastrointestinal diseases.

Shupeng Jiang, Zixuan Zhang, Jiji Zhu, Mengmeng Ji, Luying Jiang, Shilang Fan, Houjuan Zuo2026-10-16
📄 medicine

Gut Microbiota-Derived Hexanoic Acid Mediates the Protective Effects of Electroacupuncture Against Sepsis Through Macrophage Reprogramming

This study demonstrates that electroacupuncture alleviates sepsis-induced liver injury by remodeling the gut microbiota to increase *Lactobacillus vaginalis*-derived hexanoic acid, which suppresses pro-inflammatory macrophage polarization via BMAL1/NF-κB signaling, and further enhances therapeutic efficacy through an INT-777-functionalized pH-responsive liposomal delivery system.

Shifan Yan, Zehong Liu, Jun Xiong, Daocheng Zhu, Li Chen, Yu Jiang, Ting Yu2026-10-16
📄 medicine

Effects of intermittent pinpoint thermal stimulation using electronic moxibustion on cardiovascular responses: a randomized crossover study

This randomized crossover study demonstrates that intermittent pinpoint thermal stimulation at the Zusanli acupoint sustains a reduction in heart rate in healthy individuals, whereas continuous stimulation produces only a transient effect, highlighting the critical influence of temporal stimulation patterns on cardiovascular responses.

Kojirou Ito, Hidehiro Nakahara2026-10-16
📄 medicine

Effect of orthodontic treatment on systemic inflammatory biomarkers in patients with malocclusion: A Systematic Review of Randomized Controlled Trials

This systematic review of three randomized controlled trials concludes that orthodontic treatment induces a transient, self-limiting local inflammatory response in gingival crevicular fluid without a dose-dependent relationship to force magnitude, but it fails to determine effects on systemic inflammation due to the absence of studies measuring circulating biomarkers.

Fahad Aziz Khattak, Sana Ali Khan, Muhammad Usman Afridi, Aaeyla Wasif, Mahad Azhar2026-10-16