📄 medicine

Internet Addiction and Non-Suicidal Self-Injury in Adolescents with Major Depressive Disorder: The Sequential Mediating Roles of Insomnia and Depressive Symptoms

This study demonstrates that in adolescents with major depressive disorder, the link between internet addiction and non-suicidal self-injury is primarily mediated by a sequential pathway where addiction first exacerbates insomnia, which in turn worsens depressive symptoms, ultimately increasing self-injury risk.

Yudong Shi, Qing Zhang, Zhiwei Liu, Jiawei Wang, Xiangwang Wen, Huanzhong Liu2026-10-18
📄 medicine

Underutilization of Specialist Palliative Care in Acute Ischemic Stroke: A Retrospective Matched Cohort Study Identifying Clinical Referral Triggers

This retrospective matched cohort study reveals that specialist palliative care is significantly underutilized in acute ischemic stroke patients despite high symptom burdens, identifying severe functional impairment, dysphagia, and care planning difficulties as key clinical triggers for referral.

Leontinka Reutter, Joao Pinho, Arno Reich, Jörg B. Schulz, Roman Rolke, Iris Appelmann2026-10-18
📄 medicine

Risk factors for postoperative systemic inflammatory response syndrome after radical prostatectomy: development and internal validation of a prediction model

This study developed and internally validated a nomogram prediction model based on operative time, diabetes mellitus, preoperative indwelling catheterization, urinary catheter retention time, and pathologic diagnosis to effectively forecast the risk of postoperative systemic inflammatory response syndrome in patients undergoing radical prostatectomy.

Chen Yu, Luo Chen, Li Siyue, Zhu Jingzhen, Zheng Ji2026-10-18
📄 medicine

To Compare and Evaluate the Flexural Strength of Different Aligner Materials: A Randomised Clinical Study

This randomized clinical study found that while 3D-printed Graphy TC-85 resin exhibits the highest initial flexural strength, thermoformed PETG aligners demonstrate significantly superior retention of flexural strength and resistance to intraoral degradation over a 14-day wear period compared to both Graphy and TPU materials.

Varun Goyal, Deepankar Bhatnagar, Chirag Ahuja2026-10-18
📄 medicine

Preoperative central nervous system stimulant exposure and atrial fibrillation after coronary artery bypass grafting: a propensity-matched federated cohort study

This propensity-matched federated cohort study found that recorded preoperative exposure to central nervous system stimulants is associated with a modestly increased risk of postoperative atrial fibrillation or flutter following coronary artery bypass grafting, though the observational nature of the data precludes establishing causality.

Justin Lum, Andrew Jordan, Kazuhiro Hisamoto2026-10-18
📄 medicine

Single-port inflatable video-assisted mediastinoscopic transhiatal esophagectomy for esophageal cancer in a patient with left upper lobe destruction secondary to remote pulmonary tuberculosis: a case report

This case report demonstrates that single-port inflatable video-assisted mediastinoscopic transhiatal esophagectomy (SP-IVMTE) is a feasible and safe surgical alternative for esophageal cancer patients with severely compromised pulmonary function who cannot tolerate traditional transthoracic esophagectomy requiring one-lung ventilation.

Chutong Huang, Bigang Chen, Yijun Sun2026-10-18
📄 medicine

Robotic Metabolic and Bariatric Surgery: The First Reported Malaysian Series and a Propensity-Matched Comparison with Laparoscopic Surgery

This study presents the first Malaysian series of robotic metabolic and bariatric surgery, revealing a learning curve breakpoint at approximately 30 cases but demonstrating no significant superiority over laparoscopic surgery in terms of major complications or 12-month weight loss, despite a persistent 54-minute operative time premium.

Tikfu Gee, Shu Yu Lim2026-10-18
📄 medicine

Cumulative Incidence of Milestone Events in Parkinson‘s Disease: A Retrospective survey-based cohort study with Landmark Analysis

This retrospective cohort study of 126 Parkinson's disease patients utilized landmark analysis to demonstrate that while age at onset and H-Y stage are robust predictors of milestone events, the apparent protective effect of longer disease duration is a statistical artifact of left truncation, revealing that primary cumulative incidence estimates likely represent upper bounds.

Lvming Zhang, Jing Yang, Yanping Tang, Jilai Li, Yang Li, Hongmei Sun, Hui Zhu, Jichen DU, Zhirong Wan2026-10-18