📄 Category

medicine

13805 papers

📄 medicine

Development of clinical prediction models for dyssynergic defecation and rectal sensitivity in patients with functional constipation using patient-reported outcomes

This study developed and internally validated clinical prediction models using patient-reported outcomes and demographic data to effectively identify dyssynergic defecation and rectal sensory abnormalities in patients with functional constipation, offering a potential non-invasive screening tool prior to high-resolution anorectal manometry.

Xiaoxuan Wang, Xiaoyan Liu, Yu Xie2026-10-18
📄 medicine

Facilitators and Barriers to Home Use of Wearable Devices Among Older Adults With Ischemic Stroke: An Exploratory Qualitative Study

This exploratory qualitative study identifies key facilitators, such as real-time feedback and social support, and barriers, including digital literacy and data privacy concerns, that influence the adoption and sustained use of wearable devices for home-based secondary stroke prevention among older adults in China, ultimately advocating for patient-centered, age-friendly design and integrated healthcare pathways.

Nana Chen, Ranran Song, Guoxin Shi, Yulong Wang, Tingting Huang, Ying Peng, Xianping Tang, Muwei Zhu2026-10-18
📄 medicine

Effects of Periocular Acupoint Massage on Intraocular Pressure and Aqueous Humor Drainage Pathway: A Randomized, Crossover Trial

This randomized, crossover trial demonstrates that standardized periocular acupoint massage immediately lowers intraocular pressure in healthy young adults more effectively than sham stimulation by specifically expanding the aqueous humor outflow pathway and modulating autonomic function.

Min Ke, Wenjing Li, Xinying Lian, Yang Liu, Wen Zeng, Xiaomin Chen, Qing Bao, Jingqiu Huang, Pingting Ji, Nan Zhang2026-10-18
📄 medicine

Sleep quality and associated factors across four reproductive life stages in Japanese women: A cross-sectional study

This cross-sectional study of 1,213 Japanese women reveals that sleep quality varies significantly across four reproductive life stages, with mothers of infants experiencing the poorest sleep and distinct modifiable predictors—such as morning fatigue, menopausal symptoms, and screen use habits—emerging as key targets for stage-specific public health interventions.

Ayami Suga, Hiroki Moriya, Miho Kitamura, Toshio Kokubo, Akiko Tange, Hideki Ohira2026-10-18
📄 medicine

Inter-Reader Reproducibility of Quantitative Esophageal Transit Time on Preoperative Barium Esophagram

This study demonstrates that quantitative, frame-based measurement of esophageal transit time on preoperative barium esophagrams exhibits excellent reliability when averaged across three readers, while both quantitative and qualitative binary classifications at a 6-second threshold show moderate inter-reader agreement, suggesting that qualitative assessment may serve as a practical preliminary estimate.

Peter J Fernández, Sean P Duminie, Adam De Jesus, Brooklynn Rylee Rickett, David Harris, Amber Shada, Lidor, Matthew R S (…)2026-10-18
📄 medicine

Sealing the Leak: Percutaneous Deep Dorsal Penile Vein Embolization Using Glubran for Veno-Occlusive Erectile Dysfunction - A Case Report

This case report describes the first instance in the Arab region of successfully treating medically refractory veno-occlusive erectile dysfunction in a 67-year-old man using percutaneous deep dorsal penile vein embolization with a Glubran and lipiodol mixture, demonstrating the feasibility of this minimally invasive approach following a structured diagnostic workup.

Ralph Raheb-Khelo, Emilio Irani, Rashid Jaber, Karam Karam, Joe El Khoury2026-10-18
📄 medicine

Cytokine-Based Diagnostic Accuracy for Postoperative Endophthalmitis: Implications for Bacterial–Fungal Differentiation

This study demonstrates that vitreous cytokines, particularly IL-6, G-CSF, and IL-8, serve as highly accurate diagnostic biomarkers for distinguishing bacterial post-cataract endophthalmitis from non-infectious controls and moderately predict culture positivity, while also revealing that increased central macular thickness in affected eyes is not directly correlated with the measured cytokine levels.

Paulo Escarião, Henrique Escarião2026-10-18
📄 medicine

Ageism in the emergency department: Evaluating emergency medicine physicians' knowledge of and attitudes toward geriatric care in a tertiary hospital in Saudi Arabia

This study of emergency medicine physicians in a Saudi tertiary hospital reveals that while they generally hold favorable attitudes toward older adults, higher levels of geriatric knowledge and personal contact with the elderly are significantly associated with reduced ageism, highlighting the need for enhanced geriatric education and meaningful intergenerational interaction to improve emergency care.

Sarah Alghaihab, Sarah Almarwani, Maha Almarwani, Nawaf Alkharashi2026-10-18
📄 medicine

Clinical and Histologic Characteristics and Longitudinal Liver Test Changes According to GLP1R rs10305420 Genotype in Biopsy-Proven MASLD With Type 2 Diabetes

In a cohort of Japanese patients with type 2 diabetes and biopsy-proven MASLD, the GLP1R rs10305420 T-allele was associated with lower BMI and more severe liver inflammation and fibrosis, though it did not predict differential hepatic treatment responses over 12 months.

SHUNYA GOTO, Norio Akuta, Yasuka Eriksson, Shigeki Yamamoto, Yasue Takeuchi, Hitomi Sezaki, Tetsuya Hosaka, Satoshi Sait (…)2026-10-18
📄 medicine

Symptom experiences among patients with cervical cancer: a qualitative meta-synthesis

This qualitative meta-synthesis of 13 studies reveals that cervical cancer patients face complex, multidimensional symptom burdens and coping challenges, highlighting the urgent need for early symptom recognition, integrated multidimensional care, and robust multilevel support systems to improve patient-centered management.

Jiahui Mao, Xiaohui Deng, Qiuting Gu, Yanhuan Qi, Yingping Chen, Xuan Qin, Yun Chen, Xiaoting Huang, Yinqin Zhong2026-10-18