📄 Category

medicine

3760 papers

📄 medicine

Association of pulmonary function test patterns with clinical features and laboratory findings in patients with sarcoidosis: a multicenter observational study

This multicenter observational study of 590 sarcoidosis patients reveals that those presenting with restrictive pulmonary function patterns at diagnosis exhibit more advanced radiological stages, lower DLCO values, and higher treatment needs compared to those with normal or obstructive patterns, suggesting a more severe disease course requiring closer monitoring.

Selma Aydogan Eroglu, Omur Gungor, Murat Kavas, Dildar Duman, Fatma Demirci Ucsular, Gulistan Karadeniz, Nurgul Bozkurt (…)2026-07-14
📄 medicine

Multidimensional Determinants of Childhood Wasting among Children Under Five in West Africa

This study utilizes Beta Generalized Linear Mixed Models and Random Forest algorithms on World Bank data to identify agricultural water withdrawal and access to basic drinking water as the most critical, consistent determinants of childhood wasting in West Africa, recommending targeted water management and infrastructure improvements to mitigate the issue.

George Fosu Nimako, Adusei Bofa, Priscilla Felicia Tano, Christa Osei-Mensah, Georgina Afoakwah2026-07-14
📄 medicine

Evaluation of an Innovative Outpatient Palliative Care Model for Patients with Advanced Cancer: A Multicenter Randomized Clinical Trial

This multicenter randomized clinical trial found that while an innovative outpatient palliative care day hospital model did not improve overall health-related quality of life compared to traditional clinics, it significantly reduced depression symptoms in patients with advanced cancer.

Laura Marret, Amélie Anota, Mathilde Trosdorf, Aurélia Meurisse, Agnès Moura, Sophie Morin, Élise Gilbert, Damien Heitz (…)2026-07-14
📄 medicine

Hygienic compliance and food safety knowledge, attitudes and practices of food handlers in food establishments in Jalalabad city, Nangarhar province, Afghanistan

This study of 384 food handlers in Jalalabad, Afghanistan, reveals that while food safety knowledge, attitudes, and practices are generally moderate to good, the overall hygienic status of food establishments is poor, highlighting a critical need for enhanced monitoring and comprehensive training programs to improve compliance.

Sayed Attaul haq Banuree, Hayatullah Takal, Najibullah Rahimi, Fazalakbar Khalili, Mujiburahman Sadat, Sayed Ziaulhaq Ba (…)2026-07-14
📄 medicine

Disulfiram Attenuates Paraquat-Induced Renal Injury and Fibrosis Associated with Modulation of Smad3/Smad7 Expression

This study demonstrates that disulfiram, particularly at a 10 mg/kg dose, significantly attenuates paraquat-induced renal injury and fibrosis in rats by mitigating oxidative stress and rebalancing the Smad3/Smad7 signaling axis, highlighting its potential as a repurposed therapeutic agent for pesticide-induced kidney damage.

Mahtab Esmaeili, Abdolreza Daraei, Hossein Najafzadehvarzi, Soraya Khafri, Zohre Esmaeili, Yousef Beheshti, Zahra Babaza (…)2026-07-14
📄 medicine

Digital vs. Expert Assessment of Preclinical Simulation Dental Cavity Preparations at the Faculty of Dentistry, University of Benghazi

This study found that while digital assessment of dental cavity preparations using Exocad shows good reliability compared to expert grading, it systematically yields lower scores—particularly for marginal ridge thickness—suggesting a hybrid model of digital screening followed by expert review is optimal for preclinical education.

Naeima Betamar, Hana Mahjoub, Zaid El Honi, Arig Abdullah2026-07-14
📄 medicine

Prevalence, Risk Factors, and Seasonal Patterns of Chronic Obstructive Pulmonary Disease in Kabul, Afghanistan: A Cross-Sectional Study

This cross-sectional study conducted in Kabul, Afghanistan, reveals a 14.1% COPD prevalence among patients, identifying winter seasonality, indoor air pollution, passive smoking, and high rates of comorbidities as key risk factors that necessitate targeted public health interventions.

Israr Salarzai, Waheed Ullah Hafiz, Komal Najam, Saleha Yasir2026-07-14
📄 medicine

Implementing Conventional and Living Postnatal Care Guidelines in Australia: A Qualitative Study of Barriers, Facilitators, and Strategies

This qualitative study of 39 Australian interviews identifies universal barriers and facilitators to postnatal care guideline implementation while highlighting that the new national living guideline model introduces unique challenges, such as managing clinician 'change fatigue' and ensuring methodological awareness, which require tailored local strategies to optimize clinical outcomes.

Amanda K Blair, Kate Mills, Samantha P Chakraborty, Caroline S E Homer, Joshua P Vogel2026-07-14
📄 medicine

Dyslipidemia and risk of incident stroke: the mediating role of insulin resistance assessed by the triglyceride–glucose index in the CHARLS cohort

In a cohort of Chinese adults aged 45 and older, insulin resistance assessed by the triglyceride–glucose (TyG) index was found to partially mediate the association between dyslipidemia (specifically total cholesterol and HDL-C) and incident stroke risk, suggesting TyG serves as a useful adjunct marker for metabolic risk assessment beyond traditional LDL-C measures.

Yiming Huang, Xi Chen, Yujia Yan, Yang Zhang, Ming Li, Xunming Ji2026-07-14
📄 medicine

Establishing Zambia's First National Malaria RDT Proficiency Testing Programme: A Model for Strengthening Sustainable Diagnostic Capacity through South-to-South Collaboration

Through a South–South collaboration with Uganda facilitated by ECSA-HC, Zambia successfully established its first national malaria RDT proficiency testing programme, demonstrating that peer-learning models can rapidly build sustainable, high-performing diagnostic quality assurance systems aligned with regional public health goals.

Doreen Mainza Shempela, Cynthia Kasonde, Moonga Hawela, Mike Masona, Jacob Chirwa, Andrew Mwandila, Mutinta Chonga, Mais (…)2026-07-14