📄 medicine

Development of an In Vitro Denture Stomatitis Model Simulating Candida albicans Biofilm Formation and Detachment Under Daily Antiseptic Immersion

This study developed a reproducible in vitro model using standardized acrylic resin to demonstrate that daily immersion in 0.5% sodium hypochlorite or 0.12% chlorhexidine gluconate significantly reduces *Candida albicans* biofilm loads compared to water controls, providing a validated framework for evaluating denture-cleansing agents prior to clinical application.

Pornpot Jiangkongkho, Thatawee Khemwong2026-07-22
📄 medicine

Measles Vaccination Coverage, Caregiver Perceptions, and Information Sources in Five Selected Outbreak Districts of Zambia: A Descriptive Cross-Sectional Study

This cross-sectional study of 491 children in five Zambian districts reveals that while vaccination coverage appears adequate among those with records and health workers are the primary information source, the widespread lack of vaccination documentation and reliance on recall highlight critical gaps in monitoring and the need for strengthened record-keeping systems to improve measles outbreak preparedness.

Priscilla Nkonde Gardner, Dalitso Ngulube, Musole Chipoya, Kelvin Mwangilwa, Walter Azibadighi, Precious Kalubula, Lilli (…)2026-07-22
📄 medicine

Temporal Validation of a Structured Data Transformer Ensemble for 30-Day AMI Readmission Prediction

This study introduces and temporally validates the Marqi Index, a transformer-based ensemble model that achieves a 0.807 AUROC for predicting 30-day AMI readmissions using only deidentified, structured EHR and claims data, thereby addressing the lack of benchmarks for this specific data environment and outperforming existing structured-data approaches.

Xavier Serrano, Erica Oberg, Jay Pandit, Yonghui Wu, Anahita Dua2026-07-22
📄 medicine

Real-time, macroscopic shortwave infrared Raman imaging for surgical and pre-clinical applications

This paper introduces real-time, macroscopic shortwave infrared (SWIR) Raman imaging, a label-free technique that overcomes traditional autofluorescence limitations to provide high-contrast, MRI-like chemical visualization of tissue dynamics, disease markers, and critical anatomical structures for improved surgical guidance and pre-clinical diagnosis.

Oliver Bruns, Bernardo Arús, Joycelyn Yiu, Julia Barthel, Simon Härtl, Julia Correa Remus, Rudi Apolle, Jakob Lingg, Anj (…)2026-07-22
📄 medicine

Greenspace characteristics and physical activity: A systematic review and meta‑analysis of NDVI, proximity, accessibility, and morphology

This systematic review and meta-analysis of 145 studies demonstrates that higher satellite-derived greenness, closer proximity, and greater accessibility to greenspace are all significantly associated with increased physical activity, suggesting these distinct exposure metrics represent complementary pathways supporting active living.

Huaqing Wang, simin gholami, Ames Ekbatan, Louis Tassinary, Huaqing Wang2026-07-22
📄 medicine

Clinical, microbiological and antimicrobial resistance profile of complicated urinary tract infections managed in a Hospital-at-Home programme: a prospective observational cohort study

This prospective observational study of 262 complicated urinary tract infection episodes managed in a Hospital-at-Home programme demonstrates high clinical cure rates and low unplanned transfers despite a significant burden of multidrug-resistant organisms, while identifying older age and prior urological manipulation as key risk factors for 30-day readmission or death.

Lira Pelari Mici¹, Elena Arranz Canales², Alexia Constanza Espiño Álvarez², Eva María Fernández Bermejo², Ángela Sánchez (…)2026-07-22
📄 medicine

A New Therapeutic Combination of Pelvic Local Moderate Hyperthermia with HSP70 Peptide Complex Derived from Autologous Invasive Bladder Tumor in Rats

This study demonstrates that combining local moderate pelvic hyperthermia with autologous HSP70 peptide complexes significantly enhances antitumor efficacy in rats by promoting tumor cell apoptosis, inhibiting proliferation, and upregulating immune responses compared to either treatment alone.

Xiaozhen Li, Shaolin Han, Xingfu He, Xu Zhang2026-07-22
📄 medicine

Bridging the Translation Gap in Clinical AI: A Transparent Decision Support System for Cardiovascular Disease

This study presents a transparent, enterprise-grade clinical decision support system for cardiovascular disease that leverages an XGBoost model with TreeSHAP explanations integrated into a Power BI interface, achieving superior predictive accuracy (0.92 AUC-ROC) and bridging the translation gap between complex AI algorithms and actionable clinical workflows.

Yaswnth Eranyakula2026-07-22
📄 medicine

Building resilient health research ecosystems in fragile and conflict-affected situations: Scoping review of challenges and coping strategies

This scoping review maps the challenges and coping strategies for conducting health research in fragile and conflict-affected situations, identifying key barriers such as safety risks and resource constraints while highlighting the need for more quantitative research, preventive strategies, and the effective use of digital tools to build resilient health research ecosystems.

Kassahun Habtamu2026-07-22