Development of an In Vitro Denture Stomatitis Model Simulating Candida albicans Biofilm Formation and Detachment Under Daily Antiseptic Immersion
This study developed a reproducible in vitro model using standardized acrylic resin to demonstrate that daily immersion in 0.5% sodium hypochlorite or 0.12% chlorhexidine gluconate significantly reduces *Candida albicans* biofilm loads compared to water controls, providing a validated framework for evaluating denture-cleansing agents prior to clinical application.