📄 medicine

Postoperative weight-bearing beyond recommended limits following total elbow arthroplasty: Does it matter for loosening, complications, and revisions?

This retrospective study of 51 patients found that self-reported postoperative lifting beyond the standard 5-kg limit after total elbow arthroplasty was not associated with increased rates of loosening, complications, or revision surgery, suggesting that individualized counseling may be more appropriate than rigid weight restrictions.

Tamara Babasiz, Nadine Ott, Felix Krane, Lars Peter Müller, Tim Leschinger2026-09-04
📄 medicine

Geographic equity in community rehabilitation service capacity in Shanghai, China: a five-year entropy-weighted TOPSIS study

This five-year study of Shanghai's community rehabilitation centers reveals that while the demonstration-centre programme significantly improved service capacity, persistent disparities between administrative districts—rather than urban-suburban divides—highlight the need for targeted municipal support and stable investment to achieve true geographic equity.

Lingling Li, Yuhang Liu, Weigang Wang, Zhenqing Tang, Chunlin Jin, Wei Lu2026-09-04
📄 medicine

Diagnostic Value of the Antiviral Protein MxA in Viral Respiratory Tract Infections

This study demonstrates that the antiviral protein MxA serves as a highly accurate diagnostic biomarker for distinguishing viral from bacterial respiratory tract infections, showing significantly elevated levels in viral cases with an AUC of 0.810 and offering a promising tool to reduce antibiotic misuse.

Huitian Huang, Lun Huang, Bixiao Wei, Delong Xie, Siting Li, Mengli Fan, Liling Yi, Qiliu Peng2026-09-04
📄 medicine

Quality of Life and Past-Week Suicidal Ideation in Older Adults with Schizophrenia: A Sex-Moderated Analysis

This cross-sectional study of 246 hospitalized older adults with schizophrenia reveals that past-week suicidal ideation is independently associated with severe depressive symptoms, lower psychological quality of life, and higher environmental quality of life, with sex significantly moderating the protective effect of social quality of life, which was observed only in female patients.

Yinyin Fu, Ziyao Cao, Donghui Wu2026-09-04
📄 medicine

Comparison of Surgical and Conservative Treatment Outcomes in Elderly Patients with Rib Fractures: A Propensity Score-Matched Retrospective Cohort Study and Subgroup Analysis

This propensity score-matched retrospective study of 1,252 elderly patients at Shanghai Sixth People's Hospital demonstrates that surgical stabilization of rib fractures (SSRF) significantly shortens ICU stays and improves long-term quality of life compared to conservative management, despite a higher incidence of short-term pneumonia, suggesting that treatment decisions should be individualized based on patient-specific factors.

Jiaming Zhang, Yang Li, Jiazheng Huang, Ruonan Li, Weiwei He, Weiming Wu, Xiao Xie, Yonghong Zhao, Yi Yang2026-09-04
📄 medicine

Declining Rates of Orthopedic Surgery Among Patients With Multiple Myeloma- Associated Skeletal Lesions

This retrospective cohort study of over 10,000 Veterans Affairs patients reveals a significant decline in orthopedic surgical rates for multiple myeloma-associated skeletal lesions from 2008 to 2024, a trend attributed to advances in systemic therapy and bone-modifying agents despite increasing patient frailty.

Davis T. Hedbany, Cenk Yildirim, Grace M. Ferri, Nhan Do, Nathanael Fillmore, Timothy A. Damron2026-09-04
📄 medicine

Development and Characterisation of a Minimally Invasive Fixed C7 Foraminal Compression Model of Cervical Radiculopathy with Transcriptomic Identification of P2X2

This study establishes and validates a minimally invasive, fixed C7 foraminal compression rat model of cervical spondylotic radiculopathy that recapitulates key clinical and pathological features of the disease, while identifying P2X2 upregulation and associated Ca²⁺-CaMKIIα-CREB signaling as potential molecular mechanisms underlying DRG sensitization.

Wen Haonan, Shu Gao, Dong Ping, Zhang Zesong, Zhao Haibo, Xiaoyu Liu, Yang Jingning, Han Sijia, Xiao Lianbo, Chen Xiaodo (…)2026-09-04
📄 medicine

Mixed diabetic ketoacidosis and hyperosmolar hyperglycemic state in children: a retrospective cohort study of clinical characteristics, complications, and fluid management

This retrospective cohort study of pediatric patients at Namazi Hospital identifies mixed diabetic ketoacidosis and hyperosmolar hyperglycemic state as a rare (1.99% of DKA cases) but severe condition characterized by acute kidney injury and rhabdomyolysis, necessitating early diagnosis and modified fluid management to mitigate risks associated with extreme hyperosmolality.

Amir Saeed, Fatemeh sadat mirrashidi, Amir Naghshzan2026-09-04
📄 medicine

Integrating Patient Safety into Preclerkship Medical Education: A Logic Model

This paper describes the development and successful integration of a preclerkship Patient Safety Education curriculum using a logic model and backwards design approach to define 25 learning objectives across four major aims, thereby providing a roadmap for educators to weave safety content into existing medical training.

Kristin Gillenwater, Rebecca Blanchard, Christian Steciuch, Emily Diederich, Shilo Anders2026-09-04