📄 medicine

Latent Transition Analysis of Depressive Symptoms and Associated Factors Among Middle-aged and Older Adults with Cancer

This study utilized latent transition analysis on data from 285 Chinese middle-aged and older adults with cancer to identify three distinct depressive symptom profiles and their longitudinal transitions, revealing that pain severity significantly influences symptom stability and recovery, thereby highlighting the need for integrated pain and psychological monitoring.

Xiling Li, Hegen Li, Heng Yang2026-10-18
📄 medicine

Community-based primary care and inpatient costs and length of stay in Henan, China: retrospective cohort study of 5.9 million older adults

This retrospective cohort study of nearly 6 million older adults in Henan, China, found that prior enrollment in the National Essential Public Health Services elderly management program was associated with significantly lower inpatient costs and shorter hospital stays, particularly among patients with higher comorbidity burdens and longer management durations.

Jiajia Dong, Zhen Wu, Shuaijun Guo, Danni Xiao, Zhiping Guo, Qiuping Zhao, Hejia Wan, Nengguang Dai, Tong Jin, Tingting (…)2026-10-18
📄 medicine

ABC versus C-Rad Technology for Intrafraction Displacement and Dosimetric Impact in Breast Cancer Radiotherapy with Breath-Hold

While C-Rad optical surface monitoring offers significantly shorter treatment times than active breathing control (ABC) for breast cancer radiotherapy, it is associated with larger vertical intrafraction errors that increase with treatment duration, though both techniques result in only minor reductions in target coverage without significantly affecting doses to organs at risk.

Hou Longjin, Zhang Kuihao, Gao Liying, Miao Guoying, Wang Yanting, Zheng Zhangcai, Li Xiaodong2026-10-18
📄 medicine

Posttraumatic stress symptoms, alexithymia, and financial distress among adults in Beirut, Lebanon: a cross-sectional study amid overlapping crises

This cross-sectional study of 388 adults in Beirut reveals that probable PTSD, alexithymia, and financial distress are highly prevalent and interconnected, with alexithymia emerging as the strongest independent predictor of PTSD amidst Lebanon's overlapping crises.

Omar El Gharbawy, Mohamad-Tarek El Khatib, Alissar el Sibai, Lynn Kaafarani, Maria Kalash, Yara Itani, Majd Khatib, Most (…)2026-10-16
📄 medicine

Neurological, Neuromuscular, and Autonomic Manifestations of COVID-19: A Retrospective Study

This retrospective study of 72 COVID-19 patients at Cleveland Clinic Florida reveals distinct neurovascular, neuromuscular, and autonomic phenotypes characterized by significant differences in age, sex distribution, and specific clinical markers such as elevated D-dimer in stroke mortality and high rates of POTS and electrodiagnostic abnormalities.

Nestor Galvez-Jimenez, Osvaldo delgado, Raphael Bastianon Santiago, Evelio Veliz2026-10-16
📄 medicine

Cross-cultural adaptation of the University of Canberra Fast Jet Aircrew Musculoskeletal Questionnaire (UC-FJAMQ) for musculoskeletal complaint surveillance in Brazilian Air Force pilots

This study successfully performed the cross-cultural adaptation and validation of the University of Canberra Fast Jet Aircrew Musculoskeletal Questionnaire (UC-FJAMQ) for the Brazilian Air Force, resulting in a reliable, expert-validated instrument for monitoring musculoskeletal complaints across diverse military aviation operations.

Thaís de Albuquerque, Jose Roberto Andrade Nascimento Júnior, Guilherme Eugênio van Keulen, Helder Guerra de Resende, Pe (…)2026-10-16
📄 medicine

Exploring the developmental impact of internalising problems on hyperactivity/inattention symptoms in adolescence: An analysis of two UK-based longitudinal studies

Using data from two large UK longitudinal studies, this research demonstrates that internalising problems significantly exacerbate hyperactivity/inattention symptoms during adolescence, challenging the traditional view that hyperactivity/inattention is the primary causal driver of this co-occurring relationship.

Aja Louise Murray, Xinxin Zhu, Xuefei Li, Zhuoni Xiao, Yi Yang2026-10-16
📄 medicine

Pupillometric Markers of Locus Coeruleus–Norepinephrine Activity Are Associated with Internalizing Psychopathology in Adolescents

This study demonstrates that in adolescents, larger baseline pupil size (indicating heightened locus coeruleus–norepinephrine tonic activity) interacts with cortisol levels to predict internalizing psychopathology, suggesting that autonomic arousal markers offer distinct and complementary insights into stress-related mental health beyond traditional endocrine measures.

Nico Bast, Anna Katharina Müller, Christina Luckhardt, Sophia Herlitz, Anka Bernhard, Christine Margarete Freitag2026-10-16
📄 medicine

Impact of Thalidomide Addition on Health-Related Quality of Life in Transfusion-Dependent Thalassemia Patients: A Prospective Study

This prospective study conducted at Peshawar Institute of Medical Sciences demonstrates that adding thalidomide to standard therapy for transfusion-dependent thalassemia patients significantly improves health-related quality of life across all SF-36 domains while increasing hemoglobin levels and reducing transfusion requirements after six months of treatment.

Tariq Hamayun, Majid Ullah, Noor Ul Haram Khattak, Anam Zaman, Arooj Khan, Faizan Sadiq, Abdur Rehman, Muhammad Isa, Ami (…)2026-10-16