📄 Category

medicine

3760 papers

📄 medicine

Influence of Tumor Size on Survival in Pediatric and Adolescent Patients with Malignant Peripheral Nerve Sheath Tumors: A SEER Database Analysis with Single-Center Validation

This study utilizing the SEER database and validated by a single-center cohort identifies tumor size as an independent prognostic factor for survival in pediatric and adolescent patients with malignant peripheral nerve sheath tumors, establishing an optimal age-stratified cutoff of approximately 5.75 cm for risk stratification.

Qiaoyin Liu, Zhixuan Fang, Ping Chu, Yifan Liu, Yanzhen Li, Nian Sun, Junlong Tan, Zhiyong Liu, Shengcai Wang2026-07-14
📄 medicine

Parathyroid Hormone Suppression and Calcium Homeostasis Shift in Type 2 Diabetes with Osteoporosis: A Propensity Score-Matched Cross-Sectional Study

This propensity score-matched cross-sectional study reveals that in Type 2 diabetes patients with osteoporosis, bone turnover markers are comparable to those in pure diabetes, challenging the classic low-turnover hypothesis, while distinct PTH suppression with mild hypercalcemia and a weakened glycemic-bone turnover correlation suggest unique alterations in calcium homeostasis and metabolic regulation.

Xiaotian Huang, Yiwen Wang, Hao Chen, Jiaoyang Zheng2026-07-14
📄 medicine

Formulation and Development of Ligustrazine-Loaded Liposomes: A promising drug Repurposing approach for treating Nephrotoxicity

This study demonstrates that polyethyleneimine-coated Ligustrazine-loaded liposomes, developed via thin-film hydration and validated through molecular docking and in vivo rat models, effectively target the kidneys and mitigate acetaminophen-induced nephrotoxicity, offering a promising drug repurposing strategy for treating kidney damage.

Shivam Singh Chouhan, Shailendra K. Saraf, Neelam Datt2026-07-14
📄 medicine

Oral health attitudes and clinical periodontal status in Turkish undergraduate dental students: discordance between self-reported behaviour and clinical findings — a cross- sectional study

This cross-sectional study of Turkish dental students reveals that while clinical training significantly improves both self-reported oral health attitudes and objective periodontal status, a marked discordance exists between the two measures, particularly regarding gender-specific improvements in clinical findings that are not reflected in self-reported behaviors.

Gökhan Kasnak, Cenker Koyuncuoğlu, Batuhan Hazar Ayşeşek, Duygu Yaman2026-07-14
📄 medicine

Environmental determinants of Parkinson’s disease and attributable burden in Latin America

This case-control study of nearly 10,000 participants across nine Latin American countries identifies several modifiable environmental risk factors for Parkinson's disease, including pesticide and metal exposure, rural living, well water consumption, and head trauma, while confirming protective effects of caffeine and tobacco, collectively accounting for an estimated 13.7% of the disease burden in the region.

Daniel Teixeira-dos-Santos, Henry Mauricio Chaparro-Solano, Juan Felipe Duarte-Zambrano, Thiago Leal, Miguel Inca-Martin (…)2026-07-14
📄 medicine

Design of an Integrated Community-Based Strategy for Cervical Cancer Screening Access Among Women in Montería, Córdoba: The SINÚ-CCUM Intervention Proposal

The paper proposes SINÚ-CCUM, an integrated community-based intervention for Montería, Colombia, that addresses geographical, sociocultural, administrative, and operational barriers to cervical cancer screening by training a multidisciplinary team and establishing a simplified diagnostic pathway coordinated among key health stakeholders.

Javier G. Romero-Lopez, Maria Paula Torres-Barreto, Valentina Zorro Sepulveda, Valentina Vásquez Pedraza, Francisco Pale (…)2026-07-14
📄 medicine

Strengthening Primary Eye Care through Vision Centres - A 12-month analysis of Refractive Error and Cataract detection in rural Karnataka, India

This retrospective study of 8,413 patients across five rural Vision Centres in Karnataka, India, demonstrates that over a 12-month period, these facilities effectively detected refractive errors leading to a 29% spectacle conversion rate, facilitated 1,720 cataract surgeries, and integrated systemic disease screening for over 2,400 individuals.

Venkatram Katti, Lakshmi B R, Priya V. Katti, Anuja Desai, Muthulakshmi, Avinash V Prabhu2026-07-14
📄 medicine

Mechanism of Manganese Dioxide Nanomaterials Activating Stem-like CD8⁺ T Cells via Regulating Extracellular K⁺ Concentration

Manganese dioxide (MnO₂) nanomaterials enhance anti-tumor immunity by chelating excess extracellular potassium in the tumor microenvironment, thereby reversing high-K⁺-induced metabolic dysfunction and aberrant TCF7 upregulation to restore the normal function of stem-like CD8⁺ T cells.

Wenrui Hu, Youhan Liu, Mengran Cao, Ganghui Ye, Qinglu Wang, Xiaowei Li, Shenpeng Ying2026-07-14
📄 medicine

Genipin Ameliorates Experimental Rheumatoid Arthritis Through Modulation of Inflammatory Cytokines: Integrated In Vivo, Molecular Docking, and ADMET Studies

This study demonstrates that genipin effectively ameliorates experimental rheumatoid arthritis in rats by suppressing pro-inflammatory cytokines and hematological abnormalities while promoting anti-inflammatory responses, a mechanism supported by molecular docking and favorable ADMET profiles.

Hafiz Hassan Ahmed Naveed, KalimUllah KalimUllah, Sarwat Nazir, Aneeqa Saleem, Saif-Ullah Khan, Rizwana Raheel2026-07-14
📄 medicine

Interactions of strength and mobility deficits and their association with knee pain in female volleyball athletes

This study of female volleyball athletes reveals that knee pain risk is significantly driven by the interaction between specific mobility deficits (particularly foot posture and dorsiflexion range of motion) and strength limitations, where the combination of these factors creates a substantially higher likelihood of pain than either deficit alone.

Christina Frese, Friedemann Schwenkreis, Dieter Bubeck, Tobias Siebert, Fabian Tobias, Wilfried Alt2026-07-14