📄 medicine

Predictors of Functional Status and Abandonment of Tippy-Tap Handwashing Technology Following CLTS Programme Exit in Traditional Authority Chiwere, Dowa District, Malawi: A Cross-Sectional Analytical Study

This cross-sectional study in Malawi reveals that the dramatic post-programme collapse of tippy-tap handwashing technology was driven not by knowledge deficits but by household labor constraints, specifically the presence of young children and smaller household sizes, suggesting that future interventions should prioritize maintenance support for these vulnerable groups over repeated sensitization.

Precious James Mzungu¹, Ellacy Chirwa¹, Margret Soko¹, John L.Z. Nyirenda¹, Balwani Chingatichifwe Mbakaya2026-10-16
📄 medicine

Prevalence and Factors Associated with Depression among Postgraduate Students in Tanzania

This cross-sectional study of 377 postgraduate students at Muhimbili University of Health and Allied Sciences in Tanzania found that nearly 24% experienced probable depression, with financial difficulties, physical inactivity, alcohol consumption, and low social support identified as significant independent risk factors.

Salma Karim Mohamed, Elihuruma Eliufoo Stephano, Elias Bukundi, Mtoro J Mtoro, Azan Abubakar Nyundo, Idda Hubert Mosha (…)2026-10-16
📄 medicine

Intersectional Mistreatment Across Key Stages in Medical Education: A Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy

This study utilizes a multilevel intersectional analysis of Brazilian medical students to demonstrate that mistreatment prevalence varies significantly across training stages and is dynamically shaped by the intersection of social identities, particularly affecting LGBTQ+ students and revealing shifting racial disparities between basic and clinical phases.

Andréa Tenório Correia da Silva, Helena M. Constante, João L. Bastos, Ana Flávia Pires Lucas D'Oliveira, Giselle Klautau (…)2026-10-16
📄 medicine

An Evaluation of Antileishmanial and Immunomodulatory Effects of Nitazoxanide and Pentoxifylline on Leishmania Tropica in Human U937 Macrophage

This study demonstrates that a synergistic combination of nitazoxanide and pentoxifylline effectively reduces *Leishmania tropica* viability in human U937 macrophages while significantly upregulating iNOS gene expression and nitrite release, offering a promising alternative to current monotherapies for cutaneous leishmaniasis.

Khawla Adnan AlKhalidy, Sarmad Nory Gany2026-10-16
📄 medicine

Client Profiles Among Medication Treatment Episodes for Opioid Use Disorder With and Without Co-occurring Mental Health Disorders

This study analyzes 2023 US treatment data to reveal that opioid use disorder episodes involving co-occurring mental health disorders are characterized by distinct client demographics, higher rates of polysubstance use, and shorter treatment durations compared to those without such disorders, underscoring the need for integrated mental health and discharge support in medication treatment programs.

Daniel L. Howard, Kechen Zhao, Alanis Goncalves Leite, Yinfei Kong2026-10-16
📄 medicine

Postoperative Urinary Tract Infection Following Water Vapor Thermal Therapy

This international multicentre study demonstrates that applying a standardized consensus definition to postoperative urinary tract infections following water vapor thermal therapy reveals a true infection rate of 10%, significantly lower than the 21% of clinically suspected cases, thereby highlighting the importance of standardized criteria for accurate reporting and antibiotic stewardship.

Thibaut Long depaquit, Arthur Peyrottes, Alessandro Uleri, Iván Schwartzmann, Marina Fernandez-Cisneros, Maxime Vallée (…)2026-10-16
📄 medicine

Knowledge and Practices Regarding Stroke and Associated Factors among Patients Attending the Internal Medicine Outpatient Clinic at Al‑Thawra General Hospital in Ibb, Yemen

This study of 400 patients at Al-Thawra General Hospital in Yemen reveals a significant gap between moderate stroke knowledge and poor preventive practices, identifying marriage as a positive predictor of knowledge while khat chewing and smoking significantly hinder both awareness and healthy behaviors.

Safwan Al-Tahesh, AbdulraKeeb Shomais, Aref Alshabani, Wadee Abdullah Al-Shehari, Wadhah Hassan Edrees2026-10-16
📄 medicine

Striatal tissue iron in depressed and healthy individuals and the effect of buproprion

This study found that striatal tissue iron, measured via nT2*-weighted MRI, is significantly lower in depressed individuals compared to healthy controls and serves as a reliable, stable biomarker for distinguishing MDD, although it was not associated with baseline symptom severity, reward learning, or short-term response to bupropion treatment.

Helena Jeleńska, Ioana Grigoras, Rebecca Price, Annabel Walsh, Michael Browning, Catherine Harmer, Andrea Reinecke2026-10-16