13805 papers
This study analyzes longitudinal Minimum Service Standards (MSS) data for Nepal's tertiary and specialized hospitals to identify performance trends and implementation gaps, ultimately recommending strengthened accountability, digital tracking, and continuous quality improvement mechanisms to ensure MSS assessments translate into sustained healthcare enhancements.
In a study of over 2,400 Chinese adults aged 60 and older, recent increases in grip strength were found to predict better subsequent cognitive performance independent of baseline cognition, body size changes, and other covariates, suggesting that grip strength change serves as a modest longitudinal marker for cognitive health rather than a definitive causal factor.
This study presents a novel TACE potentiation strategy using hyaluronidase-degradable microspheres co-encapsulating live *Synechocystis* and the hypoxia-activated prodrug tirapazamine to convert tumor hypoxia into biohydrogen production, thereby amplifying DNA damage and immunogenic cell death to effectively suppress hepatocellular carcinoma.
This ex vivo porcine heart study demonstrates that sequential radiofrequency and pulsed field ablation, particularly when radiofrequency precedes pulsed field delivery, creates significantly deeper myocardial lesions than either modality alone while maintaining a safe thermal margin at 7 mm depth, thereby offering a promising strategy to balance ablation efficacy with the protection of adjacent structures.
This GPS-anchored cross-sectional study in Sierra Leone demonstrates that the relationship between proximity to urban abattoirs and household enteric-dermatological morbidity is entirely mediated by measurable environmental nuisance exposure rather than physical distance alone, suggesting that interventions should prioritize nuisance abatement over relocation.
In a large Korean cohort study, an extended analysis using time-varying exposure modeling confirmed a consistent but attenuated inverse association between euthyroid-range TSH and breast cancer risk, particularly in postmenopausal women, while failing to replicate a previously reported positive association between elevated FT4 and breast cancer.
In a cross-sectional study of 1,057 older adults with multimorbidity and polypharmacy, while significant differences in medication adherence were observed across nearly all five WHO dimensions, only higher disability (a patient-related factor) remained independently associated with nonadherence in multivariate analysis.
This Australian qualitative study reveals that certified interpreter involvement is essential for ethical and effective dementia care for culturally and linguistically diverse clients, yet its impact is often compromised by systemic reliance on untrained substitutes and the "talking machine" positioning of interpreters, highlighting a need for service designs that prioritize timely, professional interpreter partnerships.
This retrospective benchmark study demonstrates that while ensemble disagreement among automated landmark detectors effectively identifies gross angle-of-progression errors at low review workloads, it cannot catch failures shared by all models and offers no significant advantage between angle-space and coordinate-space metrics, necessitating local calibration for clinical deployment.
This community-based cross-sectional study in Cameroon's conflict-affected Tiko Health District reveals that while Hepatitis B virus prevalence among adolescents is intermediate (4.8%), a large proportion remains susceptible due to low vaccine-induced immunity, with internal displacement, family history, risky behaviors, and low knowledge identified as significant risk factors.