📄 Category

medicine

13805 papers

📄 medicine

Longitudinal Trajectories of Functional Dependency and Depressive Symptoms Among Middle-Aged and Older Adult Cancer Survivors: A Linear Mixed-Effects Analysis from the China Health and Retirement Longitudinal Study

Using data from the China Health and Retirement Longitudinal Study, this research reveals that middle-aged and older cancer survivors experience significantly faster deterioration in both functional dependency and depressive symptoms compared to non-survivors, with no significant differences observed between sexes.

Bochang Zhu, Yan Huang, Junqiao Zhao, Chen Zhao2026-10-14
📄 medicine

Enhancing Systems Thinking and Community-Based Innovation in Integrated Behavioral Health: A Retrospective Competency Assessment of the NJ Integrated Behavioral Health Summit

A retrospective pre/post assessment of the NJ Integrated Behavioral Health Summit demonstrates that a single-day virtual interprofessional conference significantly improved self-perceived Health Systems Science competencies and behavioral intent among diverse health professions learners, suggesting such events are scalable complements to longitudinal curricula.

Daniel Lam, Clairisse Whang, Brittany Hofferber, Rohit Mukerjee, Paul F. Weber2026-10-14
📄 medicine

VESSEL — Virtual reality education to reduce sedentary behaviour after acute stroke: protocol for a mixed-methods feasibility trial

This paper outlines the protocol for a mixed-methods feasibility trial investigating whether a one-time virtual reality education intervention delivered during acute inpatient hospitalization can effectively reduce sedentary behavior and support secondary stroke prevention in patients with minor strokes.

Annalena Paus, Stephan Hause, Grégoire Delwaulle, Markus Holling, Lukas Kühn, Markus Ramm, Frederike Riethues, Antje Sch (…)2026-10-14
📄 medicine

Comparison of two- and three-dimensional computed tomography-based deep-learning models with neurosurgeon assessments for predicting functional outcome at discharge in patients with spontaneous intracerebral hemorrhage: a single-center retrospective study

This single-center retrospective study demonstrates that deep-learning models integrating non-contrast CT scans with admission Glasgow Coma Scale scores outperform neurosurgeon assessments in predicting short-term functional outcomes for spontaneous intracerebral hemorrhage patients, with a 2D slice-based approach achieving comparable accuracy to a 3D volume-based model while requiring less clinical data.

Jichao Zhu, Yue Zhang, Yuqian Wang, Mifang Li, Gan Cao, Shanghuang Xie, Xiang Wan, Changmiao Wang, Lingyan Zhang2026-10-14
📄 medicine

Breast Cancer Evaluation and Targeted Investigational Therapy (BEAT-IT): A Pilot Prospective Tissue-Testing Study for Breast Cancer Clinical Trial Enrollment

The BEAT-IT pilot study demonstrated that prospective, biopsy-triggered multi-omics profiling in metastatic breast cancer is a feasible and safe strategy that identifies actionable genomic alterations in approximately half of patients and successfully channels nearly one-third into biomarker-matched clinical trials within a median turnaround time of 20 days.

Diego F. Chamorro, Evthokia Hobbs, Meghan Karuturi, Elyse Lopez, Lumarie Santiago, Rony Avritscher, Aysegul Sahin, Funda (…)2026-10-14
📄 medicine

Quadratus Lumborum Block for Robotic Prostatectomy: Improved Early Recovery but Not Short-Term Event-Free Survival — A Randomized Trial

This randomized trial found that while adding a quadratus lumborum block to general anesthesia for robotic prostatectomy did not significantly improve 6-month event-free survival, it substantially enhanced early recovery by reducing opioid consumption, lowering pain scores, and improving quality of recovery.

Hao Wu, Ming Xiao, Xiao Hu, Wei Huang, Jie Zhu, JunZhe Yang, BiXi Li, GuoJiang Yin, XiaoYang Song, PengFei Cheng, Xiang (…)2026-10-14
📄 medicine

Factors associated with olfactory recovery under biologic therapy in chronic rhinosinusitis with nasal polyps: the BIOPOSE prospective multicentre cohort

In a prospective multicentre cohort study of 116 patients with chronic rhinosinusitis with nasal polyps treated with biologics, a prior positive olfactory response to systemic corticosteroids and the use of dupilumab (versus mepolizumab) were identified as significant factors associated with olfactory recovery at 12 months, though the small sample size for the corticosteroid subgroup warrants further confirmation.

Benoît Wioska, Olivier Malard, Nassima Ramdane, Valentin Favier, Florent Carsuzaa, Clémentine Daveau, Emilie Béquignon (…)2026-10-14
📄 medicine

Real-world evidence of vosoritide treatment in children under 2 years of age with achondroplasia in Colombia: a cases series

This Colombian case series provides preliminary real-world evidence supporting the short-term safety and feasibility of vosoritide treatment in children under two years old with achondroplasia, while highlighting significant barriers to timely access and treatment continuity.

Leon MC, Gordillo-González G, Porras-Hurtado GL, Serrano N, Ortega R, Páez P, Garcia-Acero M2026-10-14
📄 medicine

Perioperative Butorphanol as a Multimodal Analgesic Strategy to Reduces Emergence Agitation and Attenuates Systemic Inflammation in Elderly Patients Undergoing Transurethral Resection of the Prostate: A Pragmatic Randomized Controlled Trial

This pragmatic randomized controlled trial demonstrates that perioperative butorphanol significantly reduces emergence agitation, improves immediate postoperative analgesia and sleep quality, and attenuates systemic inflammation in elderly patients undergoing transurethral resection of the prostate, offering a safe and effective opioid-sparing alternative to conventional sufentanil-based regimens.

Yixian Xiao, Defeng Sun2026-10-14