📄 Category

medicine

7905 papers

📄 medicine

Multilevel Neuroplastic Changes in Intracortical, Corticospinal, and Spinal Reflex Excitability Following Total Knee Arthroplasty: A One-Year Longitudinal Cohort Study

This one-year longitudinal study reveals that multilevel neuroplastic alterations in corticospinal, intracortical, and spinal circuits persist after total knee arthroplasty and are closely linked to incomplete quadriceps recovery, while muscle performance, rather than neurophysiological measures alone, is more directly associated with patient-reported outcomes.

Lihang Zhang, Hang Yu, Shaochen Qu, Peiyao Liang, Liming Liu, Xing Xing, Levi Agniwo, Liufeng Xiao, Shiyi Tong, Lin Guo2026-09-04
📄 medicine

Dual GIP/GLP-1 Receptor Agonist Versus Selective GLP-1 Receptor Agonist in Patients Undergoing Primary Total Knee or Hip Arthroplasty

In a propensity-matched retrospective cohort study of patients undergoing primary total knee or hip arthroplasty, tirzepatide was associated with significantly lower odds of 2-year mechanical complications and periprosthetic joint infections compared to semaglutide, despite similar outcomes at 90 days and 1 year, suggesting that dual GIP/GLP-1 agonism may offer distinct clinical benefits over selective GLP-1 agonism.

Spencer C Davis, Shlok V Patel, Shane Fletcher, John P McLaughlin, Matthew E Deren, Nicolas S Piuzzi2026-09-04
📄 medicine

Latent profiles of career-choice anxiety and associated factors among undergraduate nursing interns: a cross-sectional study

This cross-sectional study of 421 Chinese undergraduate nursing interns utilized latent profile analysis to identify four distinct career-choice anxiety groups, revealing that the high-anxiety profile was the largest subgroup and that membership in various profiles was significantly associated with core self-evaluations, family background, and major selection pathways.

Nina Gao, Fengmei Chen, Mengjia Yi, Tingting Liao, Liqun Zhu, Gaoye Li2026-09-04
📄 medicine

Healthcare professionals' conceptualisation of self-management for individuals living with Sickle Cell Disease: A qualitative study in a Ghanaian teaching hospital

This qualitative study conducted at a Ghanaian teaching hospital reveals that healthcare professionals conceptualize self-management for individuals with Sickle Cell Disease as a multidimensional process involving active patient responsibility, preventive care, and shared partnership, which is significantly shaped by social, economic, and psychological contexts.

Frank Offei Odonkor, Amidu Alhassan, Irene Korkoi Aboh, Amos Dzamefe, Yvonne Dorothy Mintah, Andrews Adjei Druye2026-09-04
📄 medicine

Fatigue is associated with stimulus-related theta and alpha power and distinguishes subjective from objective cognition in a post-viral cohort: A cross-sectional study

This cross-sectional study of post-viral individuals demonstrates that fatigue, distinct from depression, anxiety, and sleep issues, is independently associated with slower reaction times and reduced stimulus-related theta and alpha EEG power, serving as a key mediator that links subjective cognitive complaints to objective performance deficits.

Christian Neumann, Lara Godbersen, Lily Schmeer, Janka Marlene Hauffe, Katharina Helzel, Johanna Geritz, Gesine Hermann (…)2026-09-04
📄 medicine

Association of left ventricular flow and kinetic energy with myocardial strain in hypertension: insights from 4D flow MRI

This study demonstrates that 4D flow MRI reveals early impairments in left ventricular kinetic energy and flow patterns in hypertensive patients, with specific hemodynamic parameters showing independent associations with myocardial strain, thereby offering valuable tools for early risk stratification and personalized management.

Xiaolin Mu, Li Jiang, Jing Zhu, Zhe Xu, wenjia Wang, Peishi Yan, Yang Song2026-09-04
📄 medicine

Implementation fidelity of a peer-led self-help group intervention for female sex workers in Zimbabwe: A qualitative process evaluation

This qualitative process evaluation of the AMETHIST trial in Zimbabwe reveals that while peer-led self-help groups successfully addressed female sex workers' economic and psychosocial needs through savings and safe spaces, implementation fidelity was compromised by insufficient facilitator training, challenges in transitioning to independent governance, and pandemic-related disruptions, ultimately limiting the trial's ability to fully test the intended intervention model.

Gracious Madimutsa, Fortunate Machingura, Memory Makamba, Tatenda Kujeke, Albert Takaruza, Jaspar Maguma, Frances M Cowa (…)2026-09-04
📄 medicine

Food Safety and Regulatory Compliance of Sachet Alcoholic Beverages: Evidence from Heavy Metals, Labelling and Alcohol Content Discrepancies

This study of 15 sachet alcoholic beverages in Nigeria reveals significant public health risks characterized by iron contamination exceeding WHO limits, substantial misrepresentation of alcohol content, and widespread non-compliance with regulatory labeling standards, highlighting the urgent need for strengthened oversight.

Stephen Akinwusi, Ogochukwu Odeigah, Rosemary Adedokun, Augustine Onyeaghala2026-09-04
📄 medicine

Maturity of the patient registration system and factors associated with ICD-10 adoption in Côte d’Ivoire: a national analysis of the 2023 HHFA survey

A 2023 national analysis of 1,113 health facilities in Côte d'Ivoire reveals that patient registration systems are largely immature and ICD-10 adoption is limited to 15.6% of facilities, with usage significantly higher in secondary-level care settings and those equipped with internet-connected computers, highlighting an urgent need for targeted clinical coding training and infrastructure development.

Diby Jean-Paul Konan, N'dah Eric Béranger Alladé, Kraibouet Venance Wognin, Ama Isabelle Brou-N'guetta, Adama Sanogo Pon (…)2026-09-04
📄 medicine

Combined detection of plasma HSP90α with conventional tumor markers improves postoperative recurrence detection and predicts survival in advanced gastric cancer: a retrospective cohort study

This retrospective cohort study demonstrates that elevated plasma HSP90α serves as an independent adverse prognostic factor for survival in advanced gastric cancer and, when combined with conventional tumor markers, significantly improves the sensitivity of postoperative recurrence detection.

Ying Wang, Yaopeng Wang, Yitong Han, Juan Du, Maonan Wang2026-09-04