📄 Category

medicine

13396 papers

📄 medicine

How well does radiographic middle segment height loss reflect CT-defined cage–endplate penetration after zero-profile ACDF? A paired imaging study Research Article

This study demonstrates that while radiographic middle segment height loss moderately correlates with CT-defined cage–endplate penetration after zero-profile ACDF, it systematically underestimates the true depth and fails to detect 25% of cases exceeding the 2-mm threshold, indicating that radiographs are suitable for routine surveillance but insufficient for definitively ruling out significant subsidence.

Shutong Yang¹˒², Bangjun Wen¹˒², Yutao Wu¹˒², Shizhou Zhao², Aiguo Gao2026-10-22
📄 medicine

Utilising Continuous HRV Biofeedback Data for Autonomic Nervous System Regulation in ME/CFS Relapse Management

This case report demonstrates that an 11-week intervention combining continuous HRV biofeedback with expert coaching improved autonomic nervous system regulation, energy, and cognitive stability in a patient with ME/CFS, while also revealing that HRV responses to immune flares may lag behind immediate symptoms, highlighting its potential as a state-dependent early warning system for relapse management.

Kate Duder, Leanne Catchpole2026-10-22
📄 medicine

Cardiovascular Adverse Events with Anti-CD38 Antibodies Added to Identical Myeloma Regimens: A Systematic Review and Meta- analysis

This systematic review and meta-analysis of 25 multiple myeloma trials indicates that adding anti-CD38 antibodies to standard regimens significantly increases the risk of serious ischemic heart disease, arterial thromboembolism, and cardiac adverse events, warranting clinical vigilance despite the established oncologic benefits.

Aly Samy Aly, Mohamed Elmestiri, Jad Yacoub, Zaid Yacoub, Sofian Abulbida, Abubakr Elsheikh Idris2026-10-22
📄 medicine

Preoperative diffusion-perivascular MRI burden and postoperative delirium after subthalamic nucleus deep brain stimulation in Parkinson disease

This study demonstrates that a higher preoperative combined diffusion-perivascular MRI burden is significantly associated with an increased risk and severity of postoperative delirium in Parkinson's disease patients undergoing subthalamic nucleus deep brain stimulation, suggesting it as a promising candidate biomarker for perioperative neuropsychiatric vulnerability.

Chaoshi Niu, Peng Chen, Chi Xiong, Manli Jiang, Shanshan Wang, Ce Zhang, Hu He, Jianmin Si2026-10-22
📄 medicine

Beyond Explantation: Early Seroma After Immediate Post-Mastectomy Implant-Based Breast Reconstruction - A Retrospective Cohort Study

This retrospective cohort study of 135 immediate implant-based breast reconstructions identifies axillary lymph node dissection and higher pre-removal drain output as key risk factors for early seroma, demonstrating that a stepwise management strategy can successfully salvage implants in 86.7% of cases without necessitating explantation.

Michele P. Grieco, Simona Solari, Vincenzo La Montagna, Martina Iuliano2026-10-22
📄 medicine

A Randomized Controlled Trial of a Symptom Management Intervention for Post Treatment Cancer Survivors and Their Informal Caregivers Living in Rural or Urban Areas

This randomized controlled trial demonstrates that an adaptive telephone-based symptom management intervention significantly reduced symptom severity and anxiety for post-treatment cancer survivors and their caregivers, with notably greater benefits observed among rural residents and Hispanic participants compared to their urban and non-Hispanic White counterparts.

Chris Segrin, Terry A. Badger, Nathan Cunicelli, Mary C Hadeed, Alejandro Recio-Boiles, Sima Ehsani, Alla Sikorskii2026-10-22
📄 medicine

A Pigmented Intraventricular Tumor in a 10-Year-Old Girl: A Diagnostic Conundrum between Meningeal Melanocytoma and Melanotic Ependymoma with Integrated DNA Methylation and Next-Generation Sequencing Findings

This paper reports a rare case of a pigmented intraventricular tumor in a 10-year-old girl that was diagnostically challenging between meningeal melanocytoma and melanotic ependymoma but was ultimately classified as a WHO grade 1 meningeal melanocytoma through integrated histopathology, immunohistochemistry, and negative genomic findings following gross-total resection.

Celi Wang, Yidan Cao, Yifeng Shi2026-10-22
📄 medicine

Unintended pregnancy and long-term maternal mental health: findings from the Generation R Study.

This study of 8,496 women from the Generation R cohort reveals that unintended pregnancies accompanied by ambivalent feelings are associated with increased long-term maternal depressive and anxiety symptoms up to 17 years postpartum, a relationship that weakens over time and is partially mediated by perceived social support.

Adriana P. C. Hermans, Eline M. Poels, Hilmar Bijma, Manon H.J. Hillegers, Hanan El Marroun, Clair A. Enthoven2026-10-22
📄 medicine

Mechanism by Which Guben Zhuyu Decoction Repairs Impaired Osteogenesis in Glucocorticoid-Induced Osteonecrosis of the Femoral Head: Inhibition of the Mitochondrial Apoptotic Pathway by Targeting the PI3K/AKT Signaling Pathway

This study demonstrates that Guben Zhuyu Decoction (GBZY) repairs impaired osteogenesis in glucocorticoid-induced osteonecrosis of the femoral head by activating the PI3K/AKT signaling pathway to inhibit the mitochondrial apoptotic pathway, thereby promoting bone formation and preventing cell death.

Guochen Wang, Yan Zhong, Yu Bai, Guoyong Zhang, Chengan Yang, Yuliang Cai, Yi Qu, Xinghua Jiang, Xudong Zhang, Wenjun Ca (…)2026-10-22
📄 medicine

Time toxicity experiences and dyadic coping among older patients with liver cancer and their caregivers

This qualitative study reveals that time toxicity in older liver cancer patients and their caregivers encompasses both explicit logistical burdens and implicit psychological costs, which are significantly shaped by dyadic coping mechanisms, suggesting that interventions should target both healthcare processes and relational coping strategies to improve quality of life.

Jiahui Kang, Yu Wang, Sifan Liu, Jinglan Fei2026-10-22