📄 Category

medicine

7905 papers

📄 medicine

Comparison of Standard (7–14 Days) versus Extended (>14 Days) Intravenous Antibiotic Treatment for Vesicoureteral Reflux-Associated Acute Pyelonephritis in Children: A Retrospective Cohort Study

This retrospective cohort study of 99 children with vesicoureteral reflux-associated acute pyelonephritis found that extending intravenous antibiotic treatment beyond 14 days provided no significant benefit over the standard 7–14 day regimen in reducing recurrence rates, total infection episodes, or adverse outcomes.

Huimin Chen, Mo Wang, Gaofu Zhang2026-09-04
📄 medicine

Utility of the Delta/Alpha Ratio as a Neurophysiologic Marker for Children with Posterior Fossa Syndrome: A Blinded Controlled Pilot

This blinded controlled pilot study demonstrates that an elevated delta/alpha ratio (DAR) in frontal cortical regions serves as a promising neurophysiologic marker for posterior fossa syndrome in children following tumor resection, showing significant correlation with the severity of ataxia and speech deficits.

Sharyl Samargia-Grivette, Anne Bendel, Maggie Skrypek, Emma Olberg, Caroline Dahlke, Yu Liu, Callie Showalter, Amanda Ja (…)2026-09-04
📄 medicine

Machine learning prediction of clinical trajectories after N-terminal pro-B-type natriuretic peptide exceeds 35,000 pg/mL: a retrospective development and external validation study

This retrospective study developed and externally validated a machine learning model using routinely available variables to predict short-term in-hospital clinical trajectories (specifically alive discharge or NT-proBNP normalization) following an initial N-terminal pro-B-type natriuretic peptide result exceeding 35,000 pg/mL, demonstrating moderate discrimination that is primarily driven by survival outcomes rather than biochemical recovery.

Kunyang He, Di Hu, Li Li, Zongqi Pan, Xiaoping Fan2026-09-04
📄 medicine

Healthcare Utilization among Internally Displaced Persons in Camps and Hosting Communities after a Decade of the Yemeni Conflict

A cross-sectional survey conducted in August 2025 reveals that while internally displaced persons in Yemen's camps and hosting communities maintain high healthcare utilization rates despite severe financial barriers, they face significant economic hardships and require urgent, targeted financial protection and pediatric-focused interventions to sustain health outcomes.

Yahia Ahmed Raja'a, Bushra M Jaadan2026-09-04
📄 medicine

CCTA-derived anatomical features and exploratory risk stratification of severe stent-jailed left circumflex coronary artery narrowing for non-true left main bifurcation lesions

This multicenter retrospective study utilized CCTA to identify four key anatomical features—specifically a left anterior descending artery–LCX vessel angle ≤ 86°, distal left main area stenosis ≥ 54%, ostial LCX area stenosis ≥ 63%, and left main distal calcium thickness ≥ 0.5 mm—and derived an exploratory risk score with a C-statistic of 0.877 to predict severe stent-jailed left circumflex narrowing in patients undergoing provisional stenting for non-true left main bifurcation lesions.

Masaaki Okutsu, Takashi Kajiya, Kazumasa Kurogi, Yasuhiro Nakano, Kenji Sadamatsu, Yoshihide Fujimoto, Katsuyuki Hasegaw (…)2026-09-04
📄 medicine

Comparative Dosing of Bevacizumab for Radiation Necrosis: Impact of Tumor Type on Edema Response

This retrospective multicenter study suggests that while lower-dose bevacizumab (7.5 mg/kg) was initially associated with better edema reduction, this advantage was largely confounded by tumor type, ultimately indicating that the lower dose is sufficient for controlling radiation necrosis and supporting an individualized dosing approach.

Sydney E. Schultz, Milisia Labib, Jeff Breit, Jason Barreto, Carolyn Mead-Harvey, Mohamad Behairy, Aylin Nurioglu, Jessi (…)2026-09-04
📄 medicine

Evaluation of EQ-5D-5L and WOMAC Instruments in Assessing Health-Related Quality of Life Among Women Over 40 with Knee Osteoarthritis and Obesity

This cross-sectional study of 62 women over 40 in Chennai found that knee osteoarthritis, particularly when combined with obesity, significantly impairs health-related quality of life as measured by the EQ-5D-5L and WOMAC instruments, highlighting the need for enhanced social and clinical support.

M Suganya Aravazhi, Bhuvaneshwari Gunasekar2026-09-04
📄 medicine

Comparison of Health-Related Quality of Life and Other Patient-Reported JAMAR Outcomes Across Common Juvenile Idiopathic Arthritis Subtypes: A Cross-Sectional Study

This cross-sectional study of 101 Iranian children with juvenile idiopathic arthritis (JIA) found that while systemic JIA is associated with the greatest overall impairment in health-related quality of life, polyarticular JIA presents with the poorest physical function, pain, and overall well-being, indicating that subtype-specific multidisciplinary management is necessary.

Erfan Sabouri, Elahe Kaveh, Seyyed Reza Raeeskarami, Vahid Ziaee, Banafsheh Sedaghat2026-09-04
📄 medicine

CSF Diversion Facilitates Further Systemic Therapy in Leptomeningeal Hydrocephalus

This retrospective study of 51 patients demonstrates that CSF shunting for leptomeningeal disease-associated hydrocephalus provides significant symptomatic relief and facilitates the administration of subsequent CNS-penetrating therapies, which are independently associated with improved overall survival.

Maged T. Ghoche, Neslihan Nisa Gecici, Kenji Miki, Fanen Yuan, Pascal O. Zinn, Kalil G. Abdullah2026-09-04
📄 medicine

Pregnancy Nausea and Vomiting: Prevalence, Treatment Preference, Impact on Daily Functioning, and Information Needs Among Pregnant Women in Slovakia

This cross-sectional study of 173 pregnant women in Slovakia reveals that nearly 70% experience nausea and vomiting of pregnancy, which significantly impairs daily functioning for most, yet nearly half receive no treatment despite a strong preference for improved education and the demonstrated superior efficacy of Xonvea® over ginger.

Simona Dandárová, Martina Sirotná, Lenka Minarčinová, Rami Saade, Jozef Záhumenský2026-09-04