📄 medicine

Exploring experiences with denial of Medical Assistance in Dying services in Canada: A qualitative study with care seekers and their families

This qualitative study of 28 interviews with care seekers and families in Canada reveals that Medical Assistance in Dying (MAiD) access is significantly hindered by inconsistent eligibility interpretations, systemic barriers, and conscientious objections, leading to patient distress and highlighting the urgent need for clearer policies, standardized training, and expanded eligibility criteria.

Anvita Dixit, Ofeibea Asare, Lindsey Santa Maria, Alexandra Ruth Kane, Harmony Lee Ada Selman, Mila Jade Phongphilack, J (…)2026-07-21
📄 medicine

Prognostic Nutritional Index and Machine Learning for Mortality Prediction in Sepsis-Associated Acute Kidney Injury: A MIMIC-IV Cohort Study

This MIMIC-IV cohort study demonstrates that the Prognostic Nutritional Index is an independent, nonlinear predictor of mortality in sepsis-associated acute kidney injury, with its integration into a random forest machine learning model significantly enhancing risk stratification and clinical utility.

Pengyan Li, Kai Zhang, Lihua Guo, Xin Liu, Yanpeng Zhang2026-07-21
📄 medicine

Oral health in cardiology patients survey Mogadishu Somalia-Turkiye recep Tayyip Erdogan Training and Research Hospital: cross-sectional study

This cross-sectional study of 300 cardiology patients at a tertiary hospital in Mogadishu, Somalia, reveals a high burden of oral health problems and low utilization of dental services, highlighting the need to integrate oral health screening and education into routine cardiovascular care despite the lack of statistically significant independent predictors for poor self-rated oral health in the adjusted analysis.

Mesut KARATAŞ, Said Mohamud SAHAL, Iftin Mohamed Osman, Ahmed Mohamed Omar2026-07-21
📄 medicine

Global burden structure of chronic kidney disease due to type 2 diabetes: a SHAP-based spatiotemporal model-attribution analysis across 203 countries and territories

This study utilizes a SHAP-based XGBoost model on Global Burden of Disease 2021 data to reveal that the relative contribution of type 2 diabetes to the global chronic kidney disease burden among adults aged 45 and older has doubled from 1990 to 2021, with the highest impacts observed in Pacific Island nations and higher Socio-demographic Index regions.

Zeyu Guo, Qais Ahmad Naseer, Zhaoyu Zhai, Yichen Guo, Fengyuan Yang, Ying Ye, Jianbo Pan2026-07-21
📄 medicine

The Prediction Model of Social Alienation Trajectory for Adolescent Idiopathic Scoliosis Patients Based on Social Ecosystem Theory: A Prospective Cohort Study

This prospective cohort study identifies three distinct social alienation trajectories in adolescent idiopathic scoliosis patients over one year and develops a highly accurate, web-based nomogram grounded in Social Ecosystem Theory to predict those at medium-to-high risk, thereby facilitating early targeted psychosocial interventions.

Lumei Huang, Jinfeng Zang, Zheyu Chen, Zhenqing Ren, Juan Li2026-07-21
📄 medicine

Haemodynamic intolerance at the de-resuscitation decision in critically ill adults: development, temporal and external validation of a prediction model across two intensive care databases

This study developed and validated a portable prediction model using routinely collected data to estimate the risk of haemodynamic intolerance within 24 hours of initiating fluid removal in critically ill adults, demonstrating stable discrimination across diverse cohorts but requiring simple recalibration to adjust for varying event prevalences before clinical implementation.

Lujun Shao, Yue Li, Cheng Xu, Huiyu Tai, Li Wang, Jinyu Shi2026-07-21
📄 medicine

Fingermark as source of DNA: Systematic Review on Recovery and Factors affecting DNA Typing

This systematic review of 78 studies from 2000 to 2025 evaluates the evolution of fingermarks as a DNA source, concluding that successful profiling relies on a complex interplay of biological, environmental, and analytical factors and requires the optimization of visualization, extraction, and amplification methods alongside emerging technologies to maximize evidential value.

Christophe Ndayizeye, Cynthia Umutoniwase, Elizabeth Lalchhanchhuahi2026-07-21
📄 medicine

Beyond Universal Guidelines: Sleep-Stratified Isotemporal Substitution of 24-Hour Movement Behaviors and Cardiovascular Risk

This prospective cohort study of UK Biobank adults demonstrates that the cardiovascular benefits of reallocating time among sedentary behavior, sleep, and physical activity are highly dependent on baseline sleep duration, revealing that short sleepers benefit most from prioritizing sleep recovery while long sleepers gain the most from replacing sleep with physical activity.

Yifan Wang, Yedong Huang, Ziheng Wang, Shiqi Ren, Jingwei Zhao, Zhichao Lu, Jian Wang, Shun Chen, Ting Zhou, Weiye Qian (…)2026-07-21
📄 medicine

Beyond knowledge: The role of digital health literacy and food environment in Iron Deficiency Anemia management among Bangladeshi university communities- A Structural Equation Modeling approach

This structural equation modeling study of 2,600 Bangladeshi university members reveals that while Iron Deficiency Anemia knowledge and health beliefs drive dietary practices, digital health literacy and a supportive food environment significantly shape these behaviors and subsequently influence symptom management and productivity.

Fouzia Akter, Akibul Islam Chowdhury, Md. Nawal Sarwer, Marium Sultana, Tasmia Tasnim2026-07-21