7905 papers
This retrospective cohort study of 2,574 critically ill children reveals that new-onset severe acute liver injury affects approximately 6% of PICU patients, is strongly associated with increased mortality, and identifies congenital heart disease as a specific risk factor for infants.
Although Spanish pediatric hemato-oncologists recognize neuropsychological sequelae as clinically significant late effects in cancer survivors, a multicenter survey reveals that diagnosis and management are hindered by heterogeneous practices, insufficient specialized resources, and a lack of standardized protocols.
In patients with IDH-wildtype glioblastoma, a higher cerebral radiation dose burden—specifically mean brain dose and volumes receiving 15–25 Gy—is independently associated with significant treatment-related lymphopenia, which in turn predicts inferior overall and progression-free survival.
This 2024 cross-sectional study of 600 adults in Zarand and Sarbisheh found that higher water hardness levels are significantly associated with increased BMI and systolic blood pressure, with these relationships moderated by demographic and lifestyle factors such as age, gender, and smoking.
This exploratory case–control study utilized untargeted plasma lipidomics to identify distinct lipid patterns, characterized by elevated lysophospholipids and oxylipins in patients versus higher sphingolipids and cholesterol sulfates in controls, that are associated with a recurrent sickle cell leg ulcer phenotype.
This study highlights that table-side assistants in robotic surgery face significant musculoskeletal pain and psychological strain, identifying specific predictors such as increased height and smaller glove size, thereby underscoring the urgent need for improved ergonomic standardization to enhance safety and performance in the operating room.
This case report demonstrates that treatment with a GLP-1 analogue in a morbidly obese patient with a BMI of 62.84 kg/m² resulted in significant weight loss and a reduction in blood pressure sufficient to discontinue antihypertensive medications, with the patient maintaining a mean blood pressure of 113/74 mmHg at a BMI of 47.37 kg/m².
This study of 318 healthcare workers in rural Ghana reveals that easy occupational access to medicines is a significant enabling factor driving high rates of self-medication, suggesting a need for improved occupational health services and medicine governance.
In an internally cross-validated ADNI cohort, adding a baseline dyadic mean of self- and informant-reported cognitive concerns to conventional predictors yielded only a small and statistically uncertain improvement in predicting progression to MCI or AD dementia, while the self-informant gap provided no additional predictive value.
A descriptive cross-sectional survey of 100 women aged 40–60 engaged in prolonged standing in Kerala, India, found that approximately 69% met the Plantar Fasciitis Pain/Disability Scale (PFPS) criterion (>35) for heel pain, indicating a high symptom burden of predominantly moderate pain in this self-selected sample, though the results do not represent the population prevalence of clinically confirmed plantar fasciitis.