📄 medicine

A Consumer Cohort Yields Accurate Step Estimates in Young and Middle Aged Adults

This study demonstrates that consumer wearable data from Fitbit users can accurately estimate population-level physical activity trends and complement national surveillance for young and middle-aged adults in countries with sufficient demographic coverage, although the data tends to overestimate activity levels in older populations.

Daniel Roggen, Daniel Roggen, Daniel Roggen, Abram Schönfeldt, Abram Schönfeldt, Abram Schönfeldt, Katarina Vukosavljevi (…)2026-09-04
📄 medicine

Information, Not AI Model Sophistication, Limits Resolution of Disease Progression in COPDGene

This study of the COPDGene cohort demonstrates that the limited resolution of COPD disease progression is primarily constrained by the informational content of the available data rather than model sophistication, as patient-matched molecular information yields only a small, reproducible improvement in distinguishing individual trajectories despite failing to enhance overall population-level prediction.

Maurice Antony Ewing2026-09-04
📄 medicine

Prediction Error Masquerades as Individual Treatment Response: A Placebo-Controlled Falsification Study in Pooled ALS Trials

This study demonstrates that in ALS trials, prognostic residuals used to identify individual treatment responses via digital twins or synthetic controls largely reflect prediction error rather than true treatment effects, as similar "responder" and "harm" rates were observed in placebo patients, underscoring the critical need for placebo-calibrated false-positive controls before interpreting such residuals as validated individual benefits.

Maurice Antony Ewing2026-09-04
📄 medicine

The Role of the Lean Six Sigma Methodology in Improving the Performance of Malnutrition Treatment Centers in Hospitals in Sana’a Governorate: A Field Study

This field study of 108 respondents across six public hospitals in Sana'a, Yemen, demonstrates that Lean Six Sigma methodology significantly enhances Therapeutic Feeding Center performance, with Technology and Information Systems and the DMAIC cycle serving as the primary predictive drivers, resulting in a 4.5–4.7 Sigma operational level for severe acute malnutrition admissions.

Hefdallah Ali Alsiyaghi, Muneer Musleh Al-Wesabi2026-09-04
📄 medicine

Rural-Urban Differences and Associated Socio-economic Factors in Menstrual Hygiene Practices among Adolescent Girls: A Comparative Study in XXX

This comparative study in Narsingdi District, XXX, reveals that while urban adolescent girls generally exhibit better menstrual hygiene practices than their rural counterparts, socio-economic class emerges as the strongest independent predictor of sanitary pad usage and hygiene frequency, underscoring the critical need for targeted interventions to address structural inequities.

Ashi Oishwik, Mahbuba Akter Shanta, Md. Al Mamunur Rashid, Shihab Uddin Suman2026-09-04