3171 papers
This scoping review of 60 articles concludes that while non-surgical management of first-time patellar dislocation should prioritize exercise rehabilitation and avoid complete immobilization, optimal outcomes depend heavily on individual patient characteristics like age and anatomy, necessitating future research to align treatment strategies with specific risk profiles.
This cross-sectional study of 209 hospitalized older adults with cataracts identified three distinct mental health literacy profiles and determined that diagnosis duration, anxiety levels, living arrangements, and primary caregivers are key factors associated with these profiles, suggesting that targeted, profile-based interventions could improve psychological support for this population.
This longitudinal study of 355 individuals reveals that despite clinical heterogeneity, most Long COVID phenotypes share a convergent immune signature characterized by persistent IL-17F upregulation and dysregulated vascular repair, offering a framework for identifying maladaptive immune-remodelling pathways as therapeutic targets.
This mixed-methods study in the Basque Country reveals that while most primary care professionals value collaboration with specialist palliative teams and view themselves as providers of primary palliative care, they face significant barriers such as workforce challenges and training gaps, highlighting the need for optimized models that balance shared responsibility with clear support structures.
This retrospective study of 153 patients demonstrates that laparoscopy is a feasible and safe treatment for acute small bowel obstruction in carefully selected patients, with conversion rates significantly reduced to under 10% through expanded inclusion criteria, the use of laparoscopic-assisted techniques, and meticulous surgical handling by experienced surgeons.
This multicenter study demonstrates that PUMA-Net, a deep learning model analyzing first- and second-trimester placental ultrasound images combined with prepregnancy BMI, effectively predicts adverse pregnancy outcomes with high accuracy across internal and external validation cohorts.
This study demonstrates that contrast-enhanced ultrasound (CEUS) features, specifically the absence of a microcystic pattern, intact capsular continuity, and hypoenhancement, significantly improve the diagnostic accuracy of distinguishing benign, borderline, and malignant adnexal masses that remain indeterminate under the IOTA simple rules.
This double-blind, randomized phase 2 trial demonstrated that the recombinant zoster vaccine candidate LZ901 is safe and immunogenic in Chinese adults aged 50–70 years, with the 100 μg dose eliciting superior antibody responses and supporting its further evaluation in a phase 3 trial.
This study characterizes China's largest chikungunya outbreak in Foshan, identifying high transmissibility concentrated in Shunde District with elevated risks for females and older adults, while demonstrating that vector control measures effectively reduced the reproduction number and highlighting the critical role of border-area surveillance in managing arboviral threats.
This study developed and validated a clinically useful risk assessment model for colorectal adenoma using LASSO and multivariable logistic regression on 883 patients, identifying key predictors such as age, gender, and medical history to facilitate early detection and personalized prevention strategies.