📄 Category

medicine

7905 papers

📄 medicine

AI as a Biological Primitive: Optimal Intervention Inversion in Paediatric Glioma Using a Simulated Tumour Primitive

This retrospective study utilizes an AI-driven inverse modeling approach on paediatric glioma data to demonstrate that fatal tumour trajectories, particularly in midline biopsy-only cases, may be significantly redirectable through optimized surgical cytoreduction and chemotherapy timing, whereas progressive trajectories remain largely unresponsive to such interventions.

Maurice Antony Ewing2026-09-04
📄 medicine

Antimicrobial Susceptibility Profiles, Multidrug Resistance Patterns, and MAR Index Analysis of Campylobacter jejuni and Campylobacter coli Isolated from Poultry and Chicken Handlers in Maiduguri, Northeast Nigeria

This study reveals that *Campylobacter jejuni* and *C. coli* isolates from poultry and handlers in Maiduguri, Nigeria, exhibit a high prevalence of multidrug resistance (57.1%) and tetracycline resistance, underscoring an urgent need for antibiotic stewardship while confirming the continued efficacy of ciprofloxacin, levofloxacin, and erythromycin as empiric treatments.

Moses Luke, Bashir Usman Malgwi2026-09-04
📄 medicine

Knowledge, Attitude, and Practice Regarding Campylobacter Infection and Associated Risk Factors Among Chicken Handlers in Live Bird Markets, Maiduguri Metropolis, Borno State, Nigeria

This cross-sectional study of chicken handlers in Maiduguri, Nigeria, reveals a critical paradox where positive attitudes toward Campylobacter infection coexist with poor knowledge and deficient practices, identifying years of market experience as the sole protective factor against infection and highlighting the urgent need for structural interventions and targeted education for new handlers.

Moses Luke, Bashir Usman Malgwi2026-09-04
📄 medicine

Quantitative Digital Pathology Assessment of Cofilin-1 Expression in Prostate Cancer: A Biopsy-Based Cohort Study with Long-Term Follow-Up

This study demonstrates that quantitative digital pathology assessment of cofilin-1 expression in prostate cancer biopsies fails to provide prognostic value beyond established clinicopathological variables, although a potential association with recurrence in a specific low-PSA-density subgroup warrants further investigation in larger cohorts.

Mariane Araujo Branco¹·², Laura Dickel Saraiva², Giulia Godoy Ferreira², Eduarda Silvestrin², Bruna Klein Brun, Vittoria (…)2026-09-04
📄 medicine

Integrating the Sustainable Development Goals into Health Professions Education in Central Asia and the Post-Soviet Space: A Scoping Review

This scoping review reveals that while Central Asian and post-Soviet countries have made strong institutional declarations regarding the integration of Sustainable Development Goals into health professions education, empirical evidence remains critically limited due to persistent post-Soviet pedagogical legacies and resource barriers, necessitating a five-pillar regional roadmap to bridge the gap between policy and practice.

Sevara Mirkhamidova2026-09-04
📄 medicine

Evaluating the Impact of Kano State Contributory Healthcare Management Agency Integration of HIV Prevention, Treatment, and Lifelong Care on Healthcare Access and Financial Sustainability in Kano State, Nigeria: A Mixed-Methods Study

This mixed-methods study demonstrates that integrating HIV care into Kano State's contributory healthcare scheme significantly improved financial protection and access for patients, though the program's long-term sustainability is currently threatened by severe reimbursement delays and an unfavorable claims-to-premium ratio requiring actuarial reform and increased state subsidies.

Rahila Aliyu Muktar, Zainab Abdulkadir, Abdulgafar Lekan Olawumi, Al-Ameen Yahya Harande2026-09-04
📄 medicine

Cross-cultural adaptation and initial psychometric evaluation of the simplified Chinese child- and parent-report versions of the Trichotillomania Scale for Children

This study validates the cross-culturally adapted simplified Chinese versions of the Trichotillomania Scale for Children (TSC-C and TSC-P) in a mainland Chinese clinical sample, confirming their two-factor structure (Severity and Distress/Impairment), strong reliability, and utility as complementary tools for assessing pediatric trichotillomania, with particularly robust evidence supporting the child-report version.

Qiang Ding2026-09-04
📄 medicine

Perioperative Outcomes and Complications of Primary versus Revision Penile Prosthesis Surgery: A Retrospective Single-Center Cohort Study

This retrospective single-center study demonstrates that while revision penile prosthesis surgery requires significantly longer operative time and shows a non-significant trend toward higher complication rates compared to primary implantation, these findings underscore the need for careful patient counseling and resource planning even within experienced programs.

Anton Moderegger, Alexander Reese, Matchima Huabkong, Oleksandr Boiko, Hendrik Fender, Axel Merseburger, Daniar Osmonov2026-09-04
📄 medicine

Feasibility and Acceptability of the Multi-Modal Approach to Preventing Suicide in Schools (MAPSS) programme in England: A cluster-randomised controlled trial

This cluster-randomised controlled trial demonstrates that the Multi-Modal Approach to Preventing Suicide in Schools (MAPSS) programme is feasible, acceptable, and safe for implementation in English secondary schools, showing promising reductions in suicidal ideation and improvements in help-seeking that support advancing to a full-scale effectiveness trial.

Prof Pooja Saini, Molly McCarthy, Sio Wynne, Laura Sambrook, Steven Lane, Ana Duarte, Kate Henderson, Neil Boardman, Sia (…)2026-09-04
📄 medicine

Role of hematological indices in predicting preeclampsia/gestational diabetes and their severity

This longitudinal cohort study demonstrates that specific hematological indices, particularly total leukocyte count and lymphocyte-to-monocyte ratio, exhibit distinct patterns during pregnancy that serve as potential early biomarkers for predicting the development and severity of preeclampsia and gestational diabetes.

Vaishali Kasture, Hemlata Pisal, Vrushali Kadam, Karuna randhir, Girija Wagh, Sanjay Gupte, Sadhana Joshi2026-09-04