medicine papers | Gist.Science

The effect of extracorporeal diaphragmatic pacing combined with treadmill training on diaphragmatic function and clinical outcomes in patients with difficult weaning

This prospective randomized controlled trial demonstrates that combining extracorporeal diaphragmatic pacing with treadmill training significantly improves diaphragmatic function and reduces the duration of mechanical ventilation in patients with difficult weaning, although it does not significantly enhance 28-day weaning success or survival rates compared to treadmill training alone.

Huan Guan, Yuan Long2026-07-21

📄 medicine

Self-reported sleep difficulty and incident treated hypertension in Australian men: chronicity and robustness to adiposity and diabetes

In a large cohort of Australian men, chronic self-reported sleep difficulty was found to predict incident treated hypertension through a predominantly non-adiposity, time-accumulating pathway, whereas transient symptoms showed no such association.

Ebenezer Afrifa-Yamoah, Emmanuel Peprah-Yamoah, Victor Opoku-Yamoah, Eric Adua2026-07-21

📄 medicine

Bond Strength of a GPDM-Based Self-Adhesive Cement Compared to Conventional Resin Cements on 3D-Printed Crown Material

This in vitro study evaluated the shear and microtensile bond strengths of four resin cements to 3D-printed crown materials, revealing that while Nova Resin cement achieved the highest shear bond strength, it exhibited the lowest microtensile bond strength compared to other tested cements.

Murat ŞENOL, Aslı Köroğlu2026-07-21

📄 medicine

Plasmalogen deficiency and purinergic stress define three metabolic axes in schizophrenia

This study utilizes targeted plasma metabolomics to identify three distinct metabolic axes in schizophrenia—plasmalogen deficiency, antipsychotic exposure, and purinergic stress—demonstrating that plasmalogen p16:0/20:4 serves as a robust biomarker for the disease while other metabolites reflect medication effects or symptom severity.

Nikita Basov, Polina Brit, Maria Lysenko, Maria Sotnikova, Disa Tekueva, Zaira Kharaeva, Artem Rogachev, Svetlana Morozk (…)2026-07-21

📄 medicine

General Self-Efficacy, Perceived Social Support, and Anxiety Symptoms in Lung Transplant Candidates: A Cross-Sectional Study

This cross-sectional study of 50 lung transplant candidates reveals that higher general self-efficacy is independently associated with lower generalized anxiety severity, whereas perceived social support showed no significant association, suggesting that assessing self-efficacy could help identify patients needing psychological support during evaluation.

Wiktoria Drop, Aleksandra Stańska2026-07-21

📄 medicine

Therapy of acute postoperative respiratory failure with autosurfactant

This study demonstrates that administering filtered and centrifuged bronchoalveolar lavage fluid (autosurfactant) obtained from a patient's healthy lung significantly improves respiratory mechanics, lung compliance, and oxygenation in individuals suffering from acute postoperative respiratory failure.

Alibek Mustafin, Adil Mustafin, Alua Sadriten, Kulsara Rustemova2026-07-21

📄 medicine

Chronic granulomatous invasive fungal sinusitis with chronic kidney disease: case report

This case report describes the first documented instance of chronic granulomatous invasive fungal sinusitis caused by *Aspergillus fumigatus* in an 85-year-old patient with chronic kidney disease, highlighting the critical need to differentiate this condition from sinonasal malignancy through early biopsy to ensure successful treatment with antifungal therapy.

Moe Kyotani, Tsuneaki Kenzaka, Tomohiro Hayashi2026-07-21

📄 medicine

Mapping School Health Nursing Models and Implementation Strategies in Low- and Middle-Income Countries: A Joanna Briggs Institute Scoping Review

This Joanna Briggs Institute scoping review of ten studies across six low- and middle-income countries reveals that school health nursing models are critically underdeveloped and fragmented, relying primarily on non-specialist or visiting staff rather than sustainable, embedded nurse-led services, thereby highlighting an urgent need for coordinated policy, recurrent financing, and intersectoral governance to advance effective implementation.

Bakhtyar Ali Shah, Dildar Muhammad, Auran Zeb, Sarosh Sher Ali, Muhammad Tahir Yousafzai2026-07-21

📄 medicine

A Nomogram Model Incorporating PVALB Expression for Individualized Prognostic Prediction in Glioma

This study identifies high PVALB expression as an independent favorable prognostic biomarker in glioma associated with reduced immunosuppressive tumor microenvironment infiltration and validates a novel nomogram integrating PVALB, IDH1 status, and WHO grade for accurate individualized survival prediction.

Xin Ding, Hangzhe Sun, Jiaqi Lin, Zhonghuai Zhang, Jian Yuan, Yuchen Jiang, Haonan Fan, Jing Yang, Anke Zhang2026-07-21

📄 medicine

Improving adverse drug reaction knowledge among Mexican healthcare professionals through an online pharmacovigilance course: a pre–post quasiexperimental study

This pre–post quasiexperimental study demonstrates that an online pharmacovigilance course significantly improved adverse drug reaction knowledge among Mexican healthcare professionals, with mean assessment scores increasing from 5.42 to 7.72 (p < 0.001).

Yamili Espejo-Iriarte, Karla J. Esquivel-García, Mario U. Perez-Zepeda2026-07-21

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