7905 papers
This phenomenological study of 19 palliative care patients identifies key indicators of the NOC "Spiritual Health" outcome—specifically meaning, purpose, and inner connectedness—to clinically operationalize this abstract dimension and thereby support the preservation of patient dignity at the end of life.
This study demonstrates that connectometry-based analysis of white matter microstructural integrity in glioblastoma patients identifies specific fiber subcomponents, particularly in the thalamic radiation and corpus callosum, whose preservation is independently associated with significantly improved overall survival.
In a Brazilian pragmatic randomized trial involving adults with type 2 diabetes, nurse-assisted teleconsultation demonstrated equitable usability and preserved patient-centered outcomes without widening digital divides, suggesting that human facilitation and primary care integration can effectively mitigate digital exclusion in universal health systems.
This case report demonstrates that SRRM2-targeted CAR-T cell therapy is a safe and effective short-term treatment for a patient with relapsed/refractory multiple myeloma and extramedullary disease, achieving a very good partial response with minimal toxicity despite eventual disease relapse.
This hospital-based study in Chengdu analyzes 666 pediatric deaths from 2018 to 2024 to reveal an age-dependent epidemiological transition from perinatal conditions in infancy to external injuries and chronic diseases in later childhood, utilizing cause-of-death chain analysis to advocate for life-course-specific prevention strategies.
Using a Nominal Group Technique with healthcare professionals, this study identifies and prioritizes both common ("horses") and rare but critical ("zebras") end-of-life trajectories in advanced breast cancer to enhance clinical recognition and improve anticipatory care.
This study characterizes beta-lactam resistance in clinical *Escherichia coli* and *Pseudomonas aeruginosa* isolates from Trinidad and Tobago, revealing significant carbapenem resistance in *P. aeruginosa* and distinct molecular resistance profiles between the two species that underscore the need for continued local surveillance.
Based on a 17-year longitudinal study of UK adults, this paper reveals that while cognitive decline does not precede osteoporosis, the onset of the condition marks a significant inflection point triggering accelerated deterioration in global cognition, episodic memory, and orientation, particularly among older adults and those with specific comorbidities.
This cross-sectional study reveals that while pneumoconiosis-related videos on Bilibili and TikTok offer moderate quality information, there is a significant mismatch between user engagement and content reliability, with TikTok's high-traffic content often being of lower quality compared to Bilibili's more in-depth educational material, highlighting an urgent need for platform-specific strategies to improve the dissemination of evidence-based occupational health guidance.
This case report describes the successful management of a 50-year-old man with refractory precipitated opioid withdrawal syndrome, which was unresponsive to standard therapies, using sedative doses of ketamine to rapidly stabilize his vital signs and alleviate severe agitation and pain.