13805 papers
In a nationwide Chinese cohort study, a higher triglyceride–cholesterol–body weight index (TCBI) was independently associated with an increased risk of incident hypertension, and this association was significantly amplified among individuals who consume alcohol.
This study demonstrates that while contemporary 177Lu-based radiopharmaceutical therapy does not cause clinically relevant renal functional deterioration, multiparametric MRI can detect subtle longitudinal tissue changes, such as increased T1 values and perfusion alterations, offering a feasible non-invasive method for renal monitoring beyond conventional assessments.
This propensity score-matched study comparing focal therapy (cryotherapy or irreversible electroporation) with radical prostatectomy for localized prostate cancer found that while radical prostatectomy offered superior failure-free survival, approximately 80% of patients treated with focal therapy remained free of radical treatment or metastasis at five years.
This cross-sectional study in Kinshasa found that while overall neurodevelopment was normal in infants and toddlers, hearing loss in preschool-aged children was significantly associated with reduced academic performance and behavioral problems, highlighting the critical need for early hearing screening.
This case report describes a postgastrectomy Japanese patient on low-dose warfarin who developed life-threatening supratherapeutic anticoagulation during S-1 therapy, illustrating how the convergence of a low warfarin dose requirement, transient renal impairment, and persistent gastrointestinal symptoms can sequentially amplify anticoagulant effects despite dose reductions.
This qualitative single-case study in an Indonesian hospital reveals that nurses experiencing the second victim phenomenon face multidimensional distress and require comprehensive organizational support—including confidential counseling, flexible work arrangements, and non-punitive management—to safeguard their well-being and professional identity.
This randomized, triple-blind, placebo-controlled trial found that while daily supplementation with 400 or 1000 IU of vitamin D3 significantly increased serum 25-hydroxyvitamin D levels in preterm infants with respiratory distress syndrome, it did not lead to significant improvements in RDS severity, oxygen therapy duration, or hospitalization length compared to standard treatment alone.
In a concurrent-period analysis of robot-assisted simple hysterectomy for endometrial cancer, the Hugo RAS system demonstrated shorter operative times and lower consumable costs compared to the da Vinci Xi, though the performance gap narrowed significantly when early-adoption learning cases were excluded, highlighting the challenge of disentangling platform-specific efficiency from initial learning curves.
This study identifies circulating lactase-phlorizin hydrolase (LPH) as a promising peripheral biomarker for acute ischemic stroke and demonstrates that central inhibition of Glb1 and galectin-3 provides synergistic neuroprotection against ischemic neuronal injury.
This paper highlights that mediastinal masses located within conventional lymph node stations may be nerve-derived schwannomas rather than lymphadenopathy, a distinction critical for accurate diagnosis and safe, nerve-preserving surgical resection.