4086 papers
This case series highlights four pediatric patients with atypical presentations of alpha-gal syndrome, such as respiratory distress, gastrointestinal issues, and chronic urticaria, demonstrating that the condition can be misdiagnosed without a high index of suspicion for tick-bite sensitization despite the absence of classic immediate food reactions.
This case report demonstrates that a single daily dose of the CGRP receptor antagonist rimegepant effectively restored hearing and resolved symptoms in a 27-year-old woman with recurrent idiopathic sudden sensorineural hearing loss and a history of migraine, supporting the concept of cochlear migraine and the potential of CGRP-targeted therapy.
This single-center retrospective cohort study demonstrates that mobile ECMO (M-ECMO) is a feasible and effective strategy for critically ill patients, offering comparable survival outcomes to in-hospital ECMO while significantly reducing total hospital length of stay.
This study demonstrates that a Support Vector Machine model utilizing combined fNIRS and motion data from an upper extremity dual-task function can effectively classify older adults with early-stage cognitive impairment, achieving 76% accuracy and a 0.86 ROC-AUC.
This case report describes a rare instance of vulvar necrotizing soft tissue infection in an 18-year-old woman with acute infectious mononucleosis, emphasizing that clinicians should maintain a high index of suspicion for this life-threatening condition even in young, otherwise healthy patients.
This case report describes a 31-year-old male with extreme hyperferritinemia and fever of unknown origin who was successfully diagnosed with Adult-Onset Still's Disease and treated with corticosteroids followed by Tocilizumab, underscoring the critical importance of early recognition and targeted therapy to prevent severe complications like macrophage activation syndrome.
This interpretive qualitative study explores the phenomenon of "rest shame" among clinical nursing postgraduates, revealing how dual-role pressures and organizational norms create psychological conflict and overwork, while recommending institutional and cultural shifts to reframe rest as compatible with professional excellence.
This cross-sectional study found that while ChatGPT generates clear, generally accurate, and patient-friendly responses regarding pathological fractures from plasma cell tumors, it demonstrates limited depth and consistency in complex multidisciplinary clinical scenarios.
This co-designed qualitative study reveals that the inconsistent implementation of reasonable adjustments across the learning disability annual health check pathway stems from reactive rather than proactive approaches involving personal, professional, and organizational factors, highlighting the need for system-level changes to effectively reduce health inequalities.
This mixed-methods study evaluating Nepal's primary healthcare system readiness for non-communicable disease management between 2020 and 2022 reveals that while readiness varies by facility type and region, overall capacity remains insufficient due to critical shortages in equipment, medicines, trained staff, and guidelines, necessitating targeted government interventions to strengthen infrastructure and supply chains.