📄 medicine

The Longest Adult Appendix Recorded: A 38-cm Mega-Appendix Presenting with Peri-Appendiceal Phlegmon Mimicking Acute Appendicitis: a case report

This case report documents the longest recorded adult appendix at 38 cm, which presented with severe peri-appendiceal inflammation and a phlegmon mimicking acute appendicitis despite having a histologically normal mucosa, suggesting that extreme length can trigger extra-luminal necrosis and abscess formation independent of intrinsic luminal disease.

Antoine Bayda, Nicola Sayegh, Fares Sayegh2026-10-14
📄 medicine

Body mass index and mortality in patients receiving Extracorporeal Membrane Oxygenation: an analysis of the Chinese extracorporeal life support registry

In a nationwide Chinese cohort of over 13,000 ECMO patients, this study reveals a nonlinear association between body mass index and in-hospital mortality, where overweight and obesity independently increase the risk of death compared to normal weight, suggesting BMI should be integrated into multidimensional risk stratification rather than used as an isolated selection criterion.

Jing Tian, Dechao Yan, Yue Li, Dian Yu, Manyi Xu, Rui Bai, Zhongtao Du, Yi Han2026-10-14
📄 medicine

Prognostic Performance of the 2-Year Kidney Failure Risk Equation and Kidney Replacement Therpay (KRT) Preparedness in Advanced CKD: Resolving Spectrum Bias in a Malaysian Cohort

In a Malaysian tertiary cohort, the 2-year Kidney Failure Risk Equation (KFRE) demonstrated superior prognostic discrimination over eGFR for predicting end-stage kidney disease progression in earlier CKD stages but required regional recalibration to correct systematic overprediction, while the high rate of catheter-dependent dialysis initiation highlighted persistent challenges in timely KRT preparedness.

Jun Min Em, Shahaznani Lee Mohd Shaharuddin, Wan Noorhayati Wan Abdullah, Fatimah Hasanah Mohd Radzi, Khai Vern Poon, Sh (…)2026-10-14
📄 medicine

Sprint-related hamstring injuries in professional football occur closer to individual maximal running speed: a matched video and tracking case–control study

This matched case–control study combining video and tracking data reveals that sprint-related hamstring injuries in professional football occur at higher absolute speeds and closer to a player's individual maximal running speed compared to non-injury sprints, with the risk of injury significantly increasing as the sprint speed approaches the player's seasonal maximum.

Aaron Miralles-Iborra, Tomás Urbán, Juan Del Coso, Roberto López-Del Campo, Ricardo Resta, Víctor Moreno-Pérez2026-10-14
📄 medicine

Postoperative methocarbamol, opioid requirements, and pain after extensive spine fusion surgery: a retrospective cohort study

In a retrospective cohort study of 1,467 adults undergoing extensive spine fusion, postoperative methocarbamol was associated with increased opioid consumption and pain scores but also correlated with a shorter hospital stay, reduced delirium, and improved oxygenation.

Ryu Komatsu, Dongsheng Yang, Yufei Li, Liu Liu, Nour El Hage Chehade, Vanessa Bou Sleiman, Rami Kamel, Marco Ibrahim, Ji (…)2026-10-14
📄 medicine

Efficacy Analysis of Allogeneic Hematopoietic Stem Cell Transplantation for Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Gene Fusions

This retrospective study of 13 patients with myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions (MLN-TK) concludes that while tyrosine kinase inhibitors serve as effective bridging therapy, allogeneic hematopoietic stem cell transplantation remains the core curative approach for achieving long-term survival in this highly heterogeneous and often misdiagnosed disease.

Zhimin Lin, Jiarui Zhou, Xingyu Cao, Ruijuan Sun, Xian Zhang, Junfang Yang, Yanli Zhao, Yue Lu2026-10-14
📄 medicine

First Adult Case of Echovirus 21–Associated Poliomyelitis-Like Myelitis Presenting with Flaccid Asymmetric Tetraparesis

This paper reports the first documented case of a 63-year-old immunosuppressed adult woman with mantle cell lymphoma who developed acute flaccid tetraparesis due to Echovirus 21–associated myelitis, a condition mimicking poliomyelitis and characterized by "snake-eye" MRI signs, highlighting the critical need for early diagnosis in immunocompromised patients to prevent misdiagnosis.

Ibrahim Farhood, Lars Schönlau, Thomas Mika, Roland Schroers, Antonios Katsounas, Mohamad Amer Nashtar, Corinna Seliger2026-10-14
📄 medicine

Long-term surgical outcomes of strabismus surgery in craniosynostosis patients

This retrospective study of 31 craniosynostosis patients undergoing strabismus surgery reveals that while short-term alignment is often achieved, long-term stability is frequently compromised by progressive exotropic drift and new-onset contralateral inferior oblique overaction, necessitating careful counseling regarding the high likelihood of reoperations and the need for ongoing surveillance.

Majid Farvardin, Maryam Shahmohammadi, Hajar Farvardin2026-10-14