📄 Category

medicine

4086 papers

📄 medicine

Evaluating the Impact of a Medical Consortium-Based Continuing Medical Education Program on Improving COPD Knowledge Among Primary Care Physicians in Jinjiang District, Chengdu: A Pre-Post Intervention Study

This pre-post intervention study demonstrates that a medical consortium-based continuing medical education program significantly enhanced COPD-related knowledge and clinical skills among 296 primary care physicians in Jinjiang District, Chengdu, validating its potential as a scalable model for strengthening chronic respiratory disease management in primary care.

Yeran Gou, Xiaobo Hu, Yongsheng Wang, Zhengxu Deng, Yanmei Wen, Jiachen Lin2026-07-15
📄 medicine

Integrated In Vivo Optical Coherence Tomography and Metabolomics in a Rabbit Model Identify Specific Metabolic Dysregulation Underlying In-Stent Neoatherosclerosis

This study utilizes integrated in vivo optical coherence tomography and untargeted metabolomics in a rabbit model to identify specific metabolic dysregulations, including altered levels of 11 key metabolites and their interaction with the Slc5a7 receptor, that underlie the progression of in-stent neoatherosclerosis.

Yan Fang, Xiawa Wang, Lei Fan, Shi Feng, Huimin Liu, Shaohong Fang, Fuman Du, Zhuozhong Wang2026-07-15
📄 medicine

Microbiota Transplant Therapy (MTT) Improves Gastrointestinal Symptoms in Children with Pitt-Hopkins Syndrome: A Randomized Clinical Trial

This randomized clinical trial demonstrates that microbiota transplant therapy is safe and effectively improves gastrointestinal symptoms and behavioral outcomes in children with Pitt-Hopkins syndrome by remodeling the gut microbiome and enhancing mitochondrial function.

Rosa Krajmalnik-Brown, James Adams, Evelyn Takyi, Manish Muchapothula, Jasmine Kirby, Carlos Robles, Emerson Fongenyam (…)2026-07-15
📄 medicine

Knowledge, Attitudes and Practices Regarding Mpox Among Health Professionals in Beira City, Central Mozambique: A Cross-Sectional Study

This cross-sectional study of 563 healthcare professionals in Beira City, Mozambique, reveals that while the majority hold favorable attitudes toward Mpox, knowledge levels are moderate and significantly influenced by age, education, professional role, and access to multiple information sources, highlighting the need for targeted training and improved surveillance integration.

Caetano Topola Raposo, Agnélio da Silva, Unicia Nyamula, Jaime Fernando, Marcelino Piquete, João Luís Manuel, Edi Fulai (…)2026-07-15
📄 medicine

Molecular Characterization and Antimicrobial Resistance of Uropathogenic Bacteria Among Elderly Residents of Nursing Care Homes in Accra, Ghana

This study characterizes the molecular profiles and antimicrobial resistance patterns of uropathogenic bacteria isolated from elderly nursing home residents in Accra, Ghana, revealing a high prevalence of multidrug-resistant Gram-negative pathogens, particularly *E. coli* and *K. pneumoniae*, carrying diverse virulence and ESBL genes.

Emmanuel Armah, Lawrencia Osae-Nyarko, Mawutor Kwame Ahiabu, Bright Idun, Isaac Agyapong, Freda Boampong Kwarteng, Queen (…)2026-07-15
📄 medicine

National Emergency Routine Immunization Coordinating Centre an emergency response to address routine immunization gaps in Nigeria: a mixed-method retrospective study

This mixed-method retrospective study demonstrates that the establishment of Nigeria's National Emergency Routine Immunization Coordination Center (NERICC) significantly improved routine immunization coverage, evidenced by a 51% increase in average Penta3 coverage across prioritized states between 2016 and 2021, highlighting the critical role of coordinated, evidence-based interventions in strengthening health systems.

Ahmed-Rufai Garba, Daniel Ali, Festus Umaru, Pius Angioha, Sulaiman Etamesor, Belinda Uba, Hadiza Hussayn Jibril, Grace (…)2026-07-15
📄 medicine

Joint Effect of Rapid Kidney Function Decline and Depressive Symptom Trajectories on New-onset Stroke: A Prospective Study Based on the CHARLS Cohort

This prospective study of 5,452 Chinese adults demonstrates that the concurrent presence of rapid kidney function decline and increasing depressive symptoms exerts a significant synergistic effect on the risk of new-onset stroke, highlighting the value of dynamic monitoring of both renal and psychological trajectories for improved stroke prevention.

Rongyong Man, Bin Wu, Xianbi Tang, Li Liu, Xi Shao, Kaifa Peng, Yushi Zhong, Kun Wu, Yilin Feng2026-07-15
📄 medicine

Smoking Patterns, Trust in Information Sources, and Beliefs About ENDS as a Smoking Cessation Aid: A Cross-Sectional Analysis of HINTS 7

This cross-sectional analysis of HINTS 7 data reveals that while current ENDS use, female gender, younger age, and high trust in scientists and family members are associated with the belief that ENDS aid smoking cessation, this belief does not significantly motivate quitting intentions among current combustible cigarette smokers.

Yu Liu, Ya-Chen Tina Shih2026-07-15
📄 medicine

Deciphering Liver-Kidney Meridian Tropism and Shared Molecular Modules of Antitumor Herbal Medicines in Ovarian, Cervical, and Bladder Cancers

This study elucidates the molecular basis for the Traditional Chinese Medicine principle of "same treatment for different diseases" in ovarian, cervical, and bladder cancers by demonstrating that liver-kidney meridian-associated herbal compounds, particularly β-sitosterol and quercetin, converge on shared hub targets (AKT1, MYC, TP53, EGF, MMP9) and the PI3K-Akt pathway to regulate tumor progression and drug resistance.

Sheng Zhang, Tian Zhang, Xiuxiu Zhu2026-07-15
📄 medicine

Perioperative outcomes for children with preoperative upper respiratory tract infection symptoms in elective non-cardiac surgery after COVID-19 pandemic at a large tertiary hospital in China: a retrospective cohort study

This retrospective cohort study of children undergoing elective non-cardiac surgery in China found that while preoperative upper respiratory tract infection symptoms were associated with increased emergence respiratory adverse events and longer PACU stays in the post-COVID-19 era, these risks were not significantly elevated in the pre-pandera period, suggesting that the impact of URTI on perioperative outcomes is modulated by the temporal context of the pandemic.

Ruochen Pan, Yuan Bi, Tianqing Yan, Jianbo Deng, Zhang Tian, Zitong Zhang, Aijun Xu2026-07-15