📄 Category

medicine

13805 papers

📄 medicine

Progesterone receptor expression is selectively reduced in adenomyosis among endometriosis-associated lesions: a cross-sectional immunohistochemical study of 118 specimens from 100 women

This cross-sectional study of 118 specimens from 100 women reveals that reduced progesterone receptor expression is a specific characteristic of adenomyosis rather than a generalized feature of all endometriosis-associated lesions, suggesting that lesion type should be considered when selecting progestin therapy.

Yu Horibe, Tomoko Yamamoto, Kei Koshimizu, Jun Kumakiri, Yoji Nagashima, Tsutomu Tabata2026-10-14
📄 medicine

Surrogate Insulin Resistance Indices as Markers of Lifetime Cardiovascular Disease Risk Across Obesity Phenotypes in Bangladeshi Adults: A Cross-sectional Study

This cross-sectional study of Bangladeshi adults demonstrates that the TyG index and TG/HDL-C ratio are effective surrogate markers for identifying elevated lifetime cardiovascular disease risk, with phenotype-specific cutoff values showing promise for improving risk stratification across different obesity phenotypes in resource-limited settings.

Aaysha Siddiqua, Tania Nusrat Shanta, C. M. Mosabber Rahman, Sifat Naisum Rahman, Tanusri Chakraborty, Md Ebrahim Molla (…)2026-10-14
📄 medicine

Predictors of readmission in adolescent anorexia nervosa: a 24- month retrospective cohort study

This 24-month retrospective cohort study of 113 Portuguese adolescents with anorexia nervosa identifies that readmission is independently predicted by comorbid depression, the need for nasogastric tube feeding during hospitalization, and missed outpatient consultations, rather than the severity of nutritional status at admission.

Joana Gaspar Cruz Ferreira, João Vasconcelos Guerra, Sara Cavaco, Liliana Castro2026-10-14
📄 medicine

Baseline prognostic factors and post-chemotherapy pathological response in primary mediastinal non-seminomatous germ cell tumors: a single-institution retrospective study

This single-institution retrospective study of 62 patients with primary mediastinal non-seminomatous germ cell tumors identifies non-pulmonary visceral metastasis, lung metastasis, and elevated pretreatment D-dimer levels as predictors of shorter relapse-free survival, while demonstrating that post-chemotherapy pathological response is a strong determinant of postoperative outcomes.

Yosuke Amano, Tatsunori Shimoi, Hidekazu Hirano, Keiko Tanabe, Hiroki Tamura, Takuro Saiki, Taro Yamanaka, Mai Hoshino (…)2026-10-14
📄 medicine

Spatial Analysis of Healthcare Access and Malaria Incidence at Puskesmas Hanura, Pesawaran District, 2026

This 2026 cross-sectional study in Pesawaran District, Indonesia, utilized spatial analysis to reveal that malaria cases in the Puskesmas Hanura area are randomly distributed without significant geographic clustering, indicating uniformly high endemicity that necessitates equitable, area-wide control strategies rather than targeted hotspot interventions, particularly for the 13.1% of residents living beyond the 5 km healthcare access threshold.

Azzah Ghardah Aljabbar¹, Agung Aji Perdana, Tri Ani Widiastuti, Nurhalina Sari2026-10-14
📄 medicine

Apatinib-Associated Nephrotic Syndrome with Membranoproliferative Glomerulonephritis and Post-Biopsy Renal Hemorrhage: A Case Report and Literature Review

This case report describes a rare instance of apatinib-induced nephrotic syndrome with membranoproliferative glomerulonephritis in a hepatocellular carcinoma patient, highlighting the necessity of intensified renal monitoring, individualized risk-benefit assessments, and careful peri-procedural management to mitigate complications such as post-biopsy hemorrhage.

Weidong Huang#, Yiling Zhu#, Tingyan Xiang, Qiankun Zhang, Mingfeng Mao, Lingfeng Huang2026-10-14
📄 medicine

Long-term Adaptive Changes in the Neovaginal Mucosa and Quality of Life Following Sigmoid Colon Vaginoplasty

This study demonstrates that while sigmoid colon vaginoplasty yields durable anatomical and functional outcomes, the neovaginal mucosa undergoes long-term adaptive changes characterized by a shift from a colonic to a vaginal-like secretory phenotype, marked by reduced mucus production but sustained AQP2 expression that supports hydration and sexual function.

Lili Cui, Jiahua Zheng, Peng Li, Mingle Zhang, Lin Zhang, Yanling Xie, Huijuan Song, Feida Du, Yanfang Du, Xianghua Huan (…)2026-10-14
📄 medicine

Change in lean body mass in pulmonary tuberculosis patients during treatment in a tertiary care hospital, Puducherry

In a study of underweight pulmonary tuberculosis patients in Puducherry, treatment resulted in a statistically significant increase in lean body mass, which accounted for approximately 58.5% of the total weight gain, with a more pronounced effect observed in males.

Saptarshi Biswas, Sonali Sarkar, C Palanivel, Dharm Prakash Dwivedi, Jaya Prakash Sahoo, Ruben Raj L2026-10-14
📄 medicine

Clinical application of a novel coronal imbalance restoration technique for global coronal balance reconstruction in adolescent idiopathic scoliosis: a retrospective cohort study

This retrospective cohort study demonstrates that a novel coronal imbalance restoration (CIR) technique guided by intraoperative fluoroscopy effectively corrects global coronal imbalance and achieves precise three-dimensional alignment in adolescent idiopathic scoliosis patients undergoing posterior corrective surgery.

Yankui Liu, Pan Zhou, Jingxuan Feng, Guoliang Sun, Xihua Wu, Dehua Liao, Hao Zheng, Zifang Huang, Lei He2026-10-14
📄 medicine

Efficacy and Safety of Intranasal Dexmedetomidine Combined with Esketamine for Premedication in Children Undergoing Laser Treatment for Burn Scars: A Randomised Self-Controlled Crossover Trial

In a randomized self-controlled crossover trial involving 24 children aged 2–6 years undergoing laser treatment for burn scars, the combination of intranasal dexmedetomidine and esketamine demonstrated superior pre-induction sedation, reduced separation anxiety and emergence delirium, and lower propofol requirements compared to esketamine alone, with no significant safety concerns.

Sarulatuya ., Juanzhao Cao, Peng Liu, Guangjun Hu, Siyu Du2026-10-14