📄 medicine

A brief pre-test relaxation protocol improves sleep initiation during diagnostic polysomnography: a randomized controlled study

This randomized controlled trial demonstrates that a brief pre-test protocol combining slow-tempo music and paced breathing significantly reduces sleep-onset latency during diagnostic polysomnography for adults with suspected obstructive sleep apnea, without significantly altering other primary respiratory or sleep-architecture metrics.

Şeyda Akbal Çufalı, Ece Şeyma Tüzel, Ömer Faruk Çufalı, Osman Cerlet, Nurcan Yurtsever Kum, Ayşe Seçil Kayalı Dinç2026-10-14
📄 medicine

Perceived Adherence to Code of Ethics and Associated Factors Among Nurses Working at Governmental and Private Hospitals of Dessie City Administration, 2024: A Comparative Study

This 2024 comparative study in Dessie City found that only 47.4% of nurses demonstrated good adherence to the code of ethics, with significantly higher adherence observed in private hospitals compared to governmental ones, and identified working in emergency units, graduation from government institutions, job satisfaction, supportive supervision, and adequate knowledge as key factors associated with better ethical adherence.

Jemal Mohammed Bahru, Mohammed Mechal Adem, Salman Birhanu Melkamu2026-10-14
📄 medicine

Sexual frequency and premature ejaculation: a systematic review and meta-analysis of prevalence, ejaculatory latency, and coital behavior

This systematic review and meta-analysis of 19 studies reveals that premature ejaculation prevalence varies significantly based on diagnostic criteria (ranging from 7.1% to 24.9%) and is associated with notably reduced coital frequency and shorter ejaculatory latency compared to controls.

Francesco Costantini Mesquita¹, Fernando Nestor Facio¹, Leandro Ynada¹, Mateus Santos¹, Daniel Muzilli¹, Thiago Fernande (…)2026-10-14
📄 medicine

Advancement Skin Grafting: A Retrospective Comparative Study of Donor-Site Morbidity Following Split-Thickness Skin Grafting

This retrospective comparative study demonstrates that a novel advancement skin grafting technique significantly reduces donor-site healing time and improves scar quality and quality of life compared to conventional split-thickness skin grafting, offering a viable option for patients with abdominal skin laxity.

Yukun Cai, Yilong Guo, Shunbing Lu, Yuanyuan Xu, Liying Kang, Ning Ma, Sen Chen, Pingping Liu, Zhe Yang, Yangqun Li2026-10-14
📄 medicine

The PTP4A3 Inhibitor KVX-053 Disrupts STAT3 and NF-κB Signaling to Preserve Endothelial Barrier Integrity in Lipopolysaccharide-Induced Acute Lung Injury

The small molecule inhibitor KVX-053 attenuates lipopolysaccharide-induced acute lung injury and endothelial barrier dysfunction in mice and human cells by targeting PTP4A3 to disrupt STAT3 and NF-κB signaling pathways, thereby reducing inflammation and preserving pulmonary integrity.

Ruben M. L. Colunga-Biancatelli, Pavel A. Solopov, Tierney Day, Dan E. Austin, Alicia E. Yu-Shan, Maria Gabriela Tosta S (…)2026-10-14
📄 medicine

Virtual Reality–Based Training in Mental Health Literacy and Health- Literate Communication: A Mixed-Methods Pilot Study with VR AI-Driven Dialogue

This mixed-methods pilot study demonstrates that a VR-based training intervention with AI-driven assessment is feasible and well-accepted by health students for improving mental health literacy, revealing a significant gap between their strong empathic performance and low proficiency in specific health-literate communication techniques.

Thomas Herbert Kokholm, Britta Jensen, Henrik Bøggild, Kristine Sørensen2026-10-14
📄 medicine

Infantile Calcifying Pseudoneoplasm of the Neuraxis (CAPNON) at the Craniocervical Junction with Postoperative Craniocervical Instability: A Case Report

This case report describes the youngest documented patient with infantile calcifying pseudoneoplasm of the neuraxis (CAPNON) at the craniocervical junction, highlighting its atypical fluid-like gross appearance, aggressive presentation, and successful management through decompression and rigid immobilization without surgical fusion.

Y Kumar, L Domecq Laplace, M Makwana, M Mathew, F Roncaroli, C Parks2026-10-14
📄 medicine

Immediate Hypersensitivity Reactions to Biologic Therapies in Psoriasis and Hidradenitis Suppurativa

This paper reports three cases of recurrent urticarial hypersensitivity to biologic therapies for psoriasis and hidradenitis suppurativa, demonstrating that intradermal testing can confirm drug allergy, guide the discontinuation of culprit agents, and facilitate successful treatment switching to alternative biologics without further reactions.

Giulia Jardim Criado, Andreia Castanheiro Castanheiro Costa, Roberta Fachini Jardim Criado2026-10-14
📄 medicine

Bone Mineral Density and Trabecular Bone Score in Adults With X-Linked Hypophosphatemia and Tumor-Induced Osteomalacia

This study demonstrates that in adults with FGF23-mediated hypophosphatemia, lumbar spine and hip bone mineral density Z-scores, along with trabecular bone score, provide excellent discriminatory accuracy for distinguishing X-linked hypophosphatemia from tumor-induced osteomalacia.

Alberth Burnier, Maria Paz Parodi, Macarena Jimenez, Luciana Pinto Valadares, Annette Madison, Danisa Ivanovic-Zuvic, Ma (…)2026-10-14