4086 papers
This quasi-experimental study demonstrates that integrating value-based reflection into the 7E teaching model for nursing rounds significantly enhances nursing students' empathy, moral sensitivity, humanistic care, and patient safety competence compared to traditional instruction.
This prospective study from a Nepalese tertiary center demonstrates that a cost-effective diagnostic strategy combining persistent acholic stool, a serum GGT cutoff of ≥384.5 U/L, and ultrasonography can effectively differentiate biliary atresia from idiopathic neonatal hepatitis, offering a high-sensitivity parallel screening approach followed by a high-specificity serial confirmation for resource-limited settings.
This retrospective cohort study developed and validated a robust 17-year risk prediction nomogram for metabolic syndrome using 11 key clinical factors, demonstrating high accuracy and clinical utility for early identification and intervention in a large population-based sample.
Using longitudinal data from 7,109 older adults and advanced causal inference methods, this study demonstrates that maintaining high estimated cardiorespiratory fitness over time significantly and independently reduces the risk of depressive symptoms, whereas rapid declines in fitness eliminate these protective benefits.
This cross-sectional study of 136 community pharmacists in Douala, Cameroon, reveals a high burnout prevalence of 65.4% that is significantly associated with annual holidays and other activities, while showing no overall link between burnout and physical activity or sleep quality, though moderate physical activity was specifically linked to a higher risk of depersonalization.
This qualitative study of Australian health professionals reveals that broad consent for future paediatric genomic research is ethically defensible and supported when accompanied by clear explanations, robust safeguards, voluntary participation, and practices that progressively involve children as their decision-making capacity develops.
This study uses a net-benefit threshold model to demonstrate that current randomized evidence fails to show anticoagulation provides a sufficient reduction in recurrent stroke to outweigh bleeding risks compared to antiplatelet therapy for cancer-associated ischemic stroke, thereby supporting the need for a confirmatory trial rather than a change in clinical practice.
This retrospective cohort study of 35 Colombian patients with radioactive iodine-refractory differentiated thyroid cancer demonstrates that tyrosine kinase inhibitors, particularly lenvatinib, provide meaningful disease control and enable surgical resection in the neoadjuvant setting within a real-world clinical practice.
This study characterizes the clinical, pathological, and molecular features of three GLI1-altered mesenchymal tumors, highlighting their distinct histological patterns, nonspecific immunophenotype, and the critical necessity of genetic confirmation for definitive diagnosis and favorable prognosis.
This CDC WONDER analysis of U.S. mortality data from 1999 to 2023 reveals that while age-adjusted death rates from concurrent atherosclerotic heart disease and heart failure initially declined, they recently surged with widening disparities across gender, race, geography, and age groups, particularly alarming increases among younger adults and non-Hispanic Black populations.