medicine papers | Gist.Science

From "Knowing" to "Doing": Unpacking the sociocultural and systemic barriers to weight management in Chinese adults within the Greater Bay Area using the COM-B model

This qualitative study of overweight adults in China's Greater Bay Area reveals that despite high health literacy, weight management is hindered by a significant "know-do gap" driven primarily by occupational time poverty and a lack of professional guidance, necessitating a shift from individual education to system-level, AI-augmented collaborative care.

Xiaoxue Wei, Diemei Liu, Guanjun Yan, Yang Liu, Qingfeng Du2026-07-14

📄 medicine

Dengue virus at the landscape scale in Cambodia: Linking climate and land use dynamics with Dengue ecology in Southeast Asia

This four-year longitudinal study in Cambodia integrates entomological, serological, and environmental data to demonstrate that *Aedes aegypti* abundance, particularly in urban and wetland landscapes, is significantly associated with dengue incidence with a 0–4 week lag, whereas *Aedes albopictus* shows no such relationship, thereby highlighting the critical role of landscape and climate dynamics in shaping dengue transmission risks.

Sahina SIDHIK, Kimly HENG, Kimsear NOV, Sokchea LAY, Sreymom KEN, Sopheak SORN, Leangyi HENG, Y Phalla, Anavaj SAKUNTABH (…)2026-07-14

📄 medicine

Characterization of multidrug-resistant diarrheagenic Escherichia coli isolated from 2009-2020 among patients with acute diarrhea at Kisumu County Referral Hospital, Kenya

This retrospective study of 181 diarrheagenic *Escherichia coli* isolates from Kisumu, Kenya (2009–2020) reveals that Enteroaggregative *E. coli* is the predominant pathotype and that over one-third of isolates are multidrug-resistant, with high rates of resistance to first-line drugs like ampicillin and trimethoprim–sulfamethoxazole underscoring the urgent need for improved stewardship and diagnostic-guided therapy.

Christopher O. Ochieng, Abednego M. Musyoki, Fredrick Kebaso, Erick C. Kipkirui, Vanessa Natasha, Ken A. Osewe, Ibrahim (…)2026-07-14

📄 medicine

Impact of three broadcasts of a French social marketing campaign to increase parental support and physical activity of adolescents aged 11-14 years: results of a prospective cohort

A prospective cohort study of 4,005 parents demonstrates that the French "Faire bouger les ados" social marketing campaign effectively increased parental support and adolescents' physical activity, with the strongest positive impacts observed among parents who recognized all three broadcast waves compared to those with fewer exposures.

Marc Tano, Damien Tessier, Hélène Escalon, Florence Rostan, Anne-Juliette Serry, Philippine Fassier2026-07-14

📄 medicine

Multilingual Community Health Workers and Preventive Care Gaps in South Asian Immigrant Populations: A Scoping Review

This scoping review reveals that the evidence base for multilingual community health workers addressing preventive care gaps among South Asian immigrants in U.S. Federally Qualified Health Centers is narrow and geographically concentrated, highlighting an urgent need for more diverse research to inform broad programmatic recommendations.

Ameesha Vasaya2026-07-14

📄 medicine

Negative Segregation of a Rare KIF1A Variant in Familial Hyperekplexia Illustrates Pitfalls in Exome Interpretation

This case report illustrates the critical importance of segregation analysis in exome sequencing by demonstrating how a rare, computationally predicted pathogenic KIF1A variant was correctly excluded as the cause of familial hyperekplexia after failing to cosegregate with the disease phenotype in an affected family member.

Cyprian Popescu2026-07-14

📄 medicine

Bidirectional modification effects of non-optimal temperature and short-term exposure to fine particulate matter on cardiovascular diseases and their different subtypes: A time-case cross-design in multiple cities

This multi-city time-case crossover study in Anhui Province reveals that short-term PM2.5 exposure and low temperatures exert significant bidirectional synergistic effects on cardiovascular mortality, particularly for acute subtypes and among the elderly, whereas high temperatures only experience unidirectional amplification by PM2.5.

Jiahui Zhou, Yueyue Zhu, Yingru Gong, Meng Cheng, Haisheng Wu, Yanlong Xu, Yuhui Wan, Jingping Ou2026-07-14

📄 medicine

Rectal Colonization with Carbapenem-Resistant Enterobacterales in Intensive Care Unit Patients: Prevalence, Clinical Outcomes, and Risk of Subsequent Infection

This retrospective study of 3,221 ICU patients reveals that rectal colonization with carbapenem-resistant Enterobacterales is prevalent (8.9%), frequently leads to subsequent infection (51.6%), and is significantly associated with increased mortality, underscoring the critical need for early detection and rigorous infection control measures.

Deniz Yüce Yıldırım, Güneş Şenol, Reyhan Yiş, Özlem Gamze Gülfidan2026-07-14

📄 medicine

Five-Year Outcomes of UKA Versus TKA in Elderly Patients With Severe Varus Deformity in Knee Osteoarthritis: The Modifying Effect of Preoperative Extensor Muscle Radiomics Quality

In elderly patients with severe varus knee osteoarthritis, unicompartmental knee arthroplasty (UKA) demonstrates comparable five-year clinical outcomes to total knee arthroplasty (TKA) with reduced surgical trauma and faster early recovery, although the early functional advantage of UKA is attenuated in patients with poorer preoperative extensor muscle quality as quantified by radiomics.

Xianyi Zhang, Jie Shang, Peijia Su, Guizhu Ji, Ziwei Xia, Youdi Xue, Hengcai Zhou, Meng Han, Chao Ma2026-07-14

📄 medicine

Radiographic phenotypes of spinal deformity in osteogenesis imperfecta: a latent class analysis

This study utilized latent class analysis on radiographic data from 62 patients with osteogenesis imperfecta to identify two distinct spinal deformity phenotypes (severe and moderate), suggesting that this probabilistic classification approach could enhance prognostic assessment and guide individualized treatment strategies.

Marcos Vaz de Lima, João Vítor da Silva Fonseca, Bruna Vasconcellos Affonso, Arthur Moretti Gonçalves, Miguel Akkari, Cl (…)2026-07-14

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