📄 Category

medicine

13805 papers

📄 medicine

Prediction of subsequent enlargement of postoperative enhancing lesions in glioblastoma multiforme using amide proton transfer magnetic resonance imaging

This study demonstrates that amide proton transfer (APT) MRI, specifically through elevated MTR asym values, can effectively differentiate and predict the subsequent enlargement of postoperative enhancing lesions in glioblastoma multiforme patients, distinguishing tumor progression from non-increasing changes like gliosis or necrosis.

Hirofumi Koike, Minoru Morikawa, Ryo Toya, Takeshi Hiu, Takayuki Matsuo, Mitsuharu Miyoshi2026-10-14
📄 medicine

Higher aerobic capacity is associated with a more favorable circulating redox profile: potential implications for cardiovascular health

This cross-sectional study of 70 healthy adults found that higher aerobic capacity and at least two hours of weekly leisure-time physical activity are independently associated with a more favorable systemic redox profile, suggesting potential cardiovascular benefits that warrant further longitudinal investigation to establish causality.

Kinga Zujko-Kowalska, Małgorzata Elżbieta Zujko, Wojciech Łaguna, Marlena Dubatówka, Jacek Jamiołkowski, Paweł Sowa, Mar (…)2026-10-14
📄 medicine

Outcomes of PSMA radioligand therapy in lymph node-only metastatic prostate cancer: seven-year results from a single centre

This single-center study of 33 patients with lymph node-only metastatic prostate cancer demonstrates that ¹⁷⁷Lu-PSMA radioligand therapy yields high PSA response rates and favorable survival outcomes with minimal toxicity, particularly in hormone-sensitive and chemotherapy-naïve patients, supporting its earlier introduction in this disease setting.

John Yaxley, Asaad Ahmad, Jakob Kohler, Finn von Eyben, William Yaxley, David Wong, Paul Vasey2026-10-14
📄 medicine

Tophi removal surgery improves the metabolic landscape of synovial tissue and serum by regulating lipid metabolism pathways

This study demonstrates that surgical removal of tophi in advanced gout patients significantly restores systemic serum metabolic homeostasis by normalizing lipid metabolism pathways and downregulating pro-inflammatory gene expression, thereby improving the overall metabolic landscape despite persistent local synovial dysregulation.

Yuqi Chen, Jianjian Dong, Lihui Tan, Dun Mao, Chenkai Jin, Lingfeng Hou, Rong Wei2026-10-14
📄 medicine

Facilitators and Barriers to Retinopathy of Prematurity Screening in a Tertiary Care Facility: A Mixed-Methods Study

This mixed-methods study at a tertiary hospital in Nigeria reveals that ROP screening coverage is low and often delayed due to systemic barriers like staffing shortages and poor follow-up, highlighting the urgent need for institutional ownership, dedicated coordination, and improved caregiver engagement to ensure sustainable and effective screening programs.

Michael Abel Alao, Mary O. Ugalahi, Yewande O. Babalola, Modupe A. Ijaduola, Oluwole I. Majekodunmi, Ayodeji M. Borokinn (…)2026-10-14
📄 medicine

Development and Multicenter Validation of an Ensemble Machine Learning Model for Symptom-Based Triage of Hepatopancreatobiliary Diseases

This study developed and validated a high-performing ensemble machine learning model that significantly improves the sensitivity of symptom-based triage for hepatopancreatobiliary diseases compared to specialist assessment, offering a promising low-cost tool for early detection in primary care and resource-limited settings.

Rahul Rahul¹, Rajan Saxena¹, Saumya Shukla², Kush Satyen Parikh¹, Sourodeep Mandal³, Shaganti Rakesh⁴, Ankit Shukla⁵, Ni (…)2026-10-14
📄 medicine

Short-Term Anatomical and Functional Outcomes After Switching to Faricimab in Therapy-Resistant Retinal Vein Occlusion–Related Macular Edema: A Real-World Study

This real-world study demonstrates that switching to faricimab in patients with therapy-resistant retinal vein occlusion-related macular edema results in significant short-term anatomical improvements, including reduced central subfield thickness and macular volume, while maintaining visual acuity and treatment intervals with a favorable safety profile.

Dilsah Körpe, Sandra Vermeirsch, Eva De Oliveira Figueiredo, Andrea Montesel, Chiara Maria Eandi2026-10-14
📄 medicine

Clinically Suspected Systemic Arterial Gas Embolism during Robotic-Assisted Bronchoscopy: a Case Report

This case report highlights a fatal instance of clinically suspected systemic arterial gas embolism during robotic-assisted bronchoscopy, demonstrating that transient intraoperative hemodynamic and ECG changes can precede delayed neurologic injury even when initial neuroimaging is negative, thereby underscoring the critical need for immediate supportive care and hyperbaric oxygen therapy without waiting for radiographic confirmation.

Brian M. Hom, Brian Rosenberg, Nicole Y. Xu, Joseph W. Szokol, Maria McCarthy2026-10-14
📄 medicine

Diagnostic accuracy of C-reactive protein and procalcitonin against blood culture in neonatal sepsis, with ROC/logistic regression analysis and antimicrobial susceptibility pattern: a prospective observational study in a South Indian neonatal intensive care unit

In a prospective study of 200 neonates in a South Indian NICU, procalcitonin demonstrated superior diagnostic accuracy and independent predictive value for blood culture-positive sepsis compared to other markers, while the bacteriological profile was dominated by ESBL-producing *Klebsiella pneumoniae*.

Arundadhi Muthukumar, Dhanalakshmi Selvakumar, Yong Yean Kong, Mythily Nagasundaram, Amudhan Murugesan2026-10-14