📄 medicine

Application of Multifeature EEG Analysis and Machine Learning in the Investigation of Neurobiological Mechanisms of Schizophrenia

This study proposes a Genetic Algorithm-based Voting ensemble learning model (GA-Voting) that integrates power spectral density, fuzzy entropy, and phase lag index features from resting-state EEG data to achieve highly accurate (99.55%) diagnosis of schizophrenia while offering new insights into its underlying neurobiological mechanisms.

Xin’e Xie, Xiaosong Cao, Shouqing Liu, Dandan Zhao, Xiyuan Mu, Fangqing Zhu, Xiaodong Luo, wanxiu xu, Yunqi Zhu, Yongwei (…)2026-07-14
📄 medicine

Scaling Village Health Leader–Led Community Maternal and Newborn Health Interventions in Underserved Ethiopian Communities: Evidence on Effectiveness, Safety, and Implementation

This study demonstrates that scaling up Village Health Leader–led community interventions in underserved Ethiopian agrarian and pastoralist settings is a feasible, safe, and effective strategy that significantly improves maternal and newborn health outcomes, including increased facility deliveries, reduced postpartum hemorrhage, and higher uptake of essential commodities like misoprostol and family planning.

Gizachew Tadele Tiruneh, Agumasie Semahegn, Nebreed Fesseha, Mesele Damte Argaw, Hillina Tadesse, Tamar Chitashvili, Ale (…)2026-07-14
📄 medicine

Adipose-derived mesenchymal stem cell-derived exosomal miR-22-3p alleviates depression-like behaviors via the FURIN/HMGB1 axis

This study demonstrates that intranasal administration of adipose-derived mesenchymal stem cell-derived exosomes engineered to deliver miR-22-3p alleviates depression-like behaviors in a rat model by inhibiting the FURIN/HMGB1 axis, thereby reducing neuroinflammation and neuronal apoptosis.

Yuxin Xu, Yanqiu You, Dekai Wei, Rong Liang, Weiping Liang, Bingzheng Feng, Jibing Chen, Jia Liang, Fujun Li2026-07-14
📄 medicine

Validation of non-stent criteria post-endoscopic stone management. Contemporary study

This contemporary study validates Hekal's "5-Not's" criteria as a reliable, high-specificity framework for identifying ideal candidates for stentless endoscopic urinary stone management, demonstrating that while the criteria effectively confirm suitability for stent-free recovery, they should not be used as an exclusive screening tool to rule out patients who fail to meet all five conditions.

Ihab A. Hekal, Jana Hekal, Yousef Hekal2026-07-14
📄 medicine

Psychometric Properties of the Spanish version of the Detail and Flexibility Questionnaire (DFlex)

This study validates a reliable and effective 10-item Spanish brief version of the Detail and Flexibility Questionnaire (DFlex) for assessing cognitive rigidity and attention to detail in individuals with eating disorders and the general population.

Javier Manchón López, Álvaro Ruiz-Maciá, Ricardo Sanmartin López, Sofía Payá-López, Katina Ilieva Kovacheva, Eva Mª León (…)2026-07-14
📄 medicine

Association of pulmonary function test patterns with clinical features and laboratory findings in patients with sarcoidosis: a multicenter observational study

This multicenter observational study of 590 sarcoidosis patients reveals that those presenting with restrictive pulmonary function patterns at diagnosis exhibit more advanced radiological stages, lower DLCO values, and higher treatment needs compared to those with normal or obstructive patterns, suggesting a more severe disease course requiring closer monitoring.

Selma Aydogan Eroglu, Omur Gungor, Murat Kavas, Dildar Duman, Fatma Demirci Ucsular, Gulistan Karadeniz, Nurgul Bozkurt (…)2026-07-14
📄 medicine

Multidimensional Determinants of Childhood Wasting among Children Under Five in West Africa

This study utilizes Beta Generalized Linear Mixed Models and Random Forest algorithms on World Bank data to identify agricultural water withdrawal and access to basic drinking water as the most critical, consistent determinants of childhood wasting in West Africa, recommending targeted water management and infrastructure improvements to mitigate the issue.

George Fosu Nimako, Adusei Bofa, Priscilla Felicia Tano, Christa Osei-Mensah, Georgina Afoakwah2026-07-14
📄 medicine

Evaluation of an Innovative Outpatient Palliative Care Model for Patients with Advanced Cancer: A Multicenter Randomized Clinical Trial

This multicenter randomized clinical trial found that while an innovative outpatient palliative care day hospital model did not improve overall health-related quality of life compared to traditional clinics, it significantly reduced depression symptoms in patients with advanced cancer.

Laura Marret, Amélie Anota, Mathilde Trosdorf, Aurélia Meurisse, Agnès Moura, Sophie Morin, Élise Gilbert, Damien Heitz (…)2026-07-14
📄 medicine

Hygienic compliance and food safety knowledge, attitudes and practices of food handlers in food establishments in Jalalabad city, Nangarhar province, Afghanistan

This study of 384 food handlers in Jalalabad, Afghanistan, reveals that while food safety knowledge, attitudes, and practices are generally moderate to good, the overall hygienic status of food establishments is poor, highlighting a critical need for enhanced monitoring and comprehensive training programs to improve compliance.

Sayed Attaul haq Banuree, Hayatullah Takal, Najibullah Rahimi, Fazalakbar Khalili, Mujiburahman Sadat, Sayed Ziaulhaq Ba (…)2026-07-14