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medicine

13805 papers

📄 medicine

Online Registry for Patent Ductus Arteriosus in Very Preterm Infants in Shenzhen: Protocol for a Multicenter, Prospective, Observational Cohort Study

This paper outlines the protocol for a multicenter, prospective, observational cohort study in Shenzhen that aims to establish China's first dedicated online registry for patent ductus arteriosus in very preterm infants to investigate its epidemiology, develop a machine learning-based predictive model for hemodynamically significant cases, and support future biomarker research through a linked biobank.

Jie Qi, Hui Wang, Hanni Lin, Xiaoli Zhao, Rui Li, Shuyu Luo, Guixuan Hong, Boshi Yu, Zihao Shen, Sien Huang, Suying Li (…)2026-10-14
📄 medicine

Anastomotic leakage and long-term survival after minimally invasive esophagectomy: a retrospective cohort study

This retrospective cohort study of 618 patients with esophageal squamous cell carcinoma demonstrates that anastomotic leakage following minimally invasive esophagectomy is independently associated with significantly inferior long-term overall survival, with the negative prognostic impact persisting across all postoperative timepoints and increasing with the intensity of required leak management.

Kaiming Peng, Guoping Hu, Shuchen Chen, Peipei Zhang, Mingqiang Kang2026-10-14
📄 medicine

The predictive value of endothelial activation and stress index (EASIX) for major adverse cardiovascular events in patients with coronary slow-flow phenomenon: a retrospective cohort study

This retrospective cohort study of 517 patients with coronary slow-flow phenomenon demonstrates that a higher endothelial activation and stress index (EASIX) is an independent predictor of major adverse cardiovascular events, suggesting its utility as a simple, readily available tool for long-term risk stratification.

Irem Yilmaz, Kurtulus Karauzum, Hooman Rahimipour, Didar Mirzamidinov2026-10-14
📄 medicine

Novel anthropometric and metabolic indices for identifying insulin resistance and body-composition abnormalities in elderly patients with type 2 diabetes: a cross-sectional study

This cross-sectional study of hospitalized elderly patients with type 2 diabetes found that TyG-based indices, particularly TyG-WC, were the only independent predictors of insulin resistance, while waist and neck circumferences served as practical markers for visceral obesity, and grip strength assessment proved crucial for identifying frequent dynapenia despite rare sarcopenia.

Rongkun Xu, Chen Qiu, Jinghui Li, Lu Lin, Mingqian Jiang, Binhua Ye2026-10-14
📄 medicine

Associations Between Confucian Coping and Psychological Symptoms in Chinese Patients with Crohn’s Disease: A Sequential Explanatory Mixed- Methods Study

This sequential explanatory mixed-methods study reveals that Confucian coping strategies among Chinese patients with Crohn's disease exhibit a dual nature, where dimensions like responsibility and resilience generally alleviate psychological distress, yet culturally embedded expectations of endurance and family obligation can simultaneously create significant emotional burdens.

zhen wang, Zhinian Shen, Bowen Xue, Meihao Wei, Linyan Yao, Jinghan Liu, Jinli Bu, Xiao Han, Hong Luo, Yiyu Zhuang2026-10-14
📄 medicine

Positional cervical Doppler ultrasonography suggesting proximal vertebral artery obstruction in Bow Hunter syndrome: a case report

This case report describes a patient with Bow Hunter syndrome who presented with dizziness and cerebellar infarctions, where positional cervical Doppler ultrasonography successfully identified intermittent proximal left vertebral artery obstruction during neck rotation, guiding subsequent imaging confirmation and conservative management.

Taibo Uchida, Yuki Kitazaki, Tomohisa Yamaguchi, Hirotoshi Hamaguchi, Noriko Matsumoto, Mayu Eguchi, Kojiro Usui, Rei As (…)2026-10-14
📄 medicine

Clinical evaluation of early ICU echocardiographic haemodynamic measures and 28-day mortality in sepsis: a retrospective cohort study

This retrospective cohort study of 3,876 sepsis patients using MIMIC-IV data found that early ICU echocardiographic measures, specifically higher stroke volume index and abnormal right heart function, are independently associated with 28-day mortality and provide modest incremental prognostic value beyond standard clinical variables.

Zheng Yao, Shijia Zhu, Zhaotao Fang2026-10-14
📄 medicine

Individual and community-level factors associated with ovulatory phase knowledge among women of reproductive age in Ethiopia: a multilevel analysis of 2024–25 Ethiopian Demographic and Health Survey data

This study analyzes 2024–25 Ethiopian Demographic and Health Survey data to reveal that only 34.73% of reproductive-aged women possess correct ovulatory phase knowledge, a low prevalence significantly influenced by individual factors like education and contraceptive awareness, as well as community-level determinants such as media exposure and regional location.

Henok Toga Wada, Asaminew Birhanu Balta2026-10-14
📄 medicine

Knowledge, Attitudes and Occupational Practices for Toxoplasmosis Prevention among Slaughterhouse and Meat Shop Workers in Benue North-West Senatorial District, Nigeria: A Cross-Sectional Study

This cross-sectional study of 400 slaughterhouse and meat shop workers in Benue State, Nigeria, reveals that despite high occupational exposure, the workforce possesses extremely poor knowledge of toxoplasmosis and engages in risky practices, highlighting an urgent need for targeted health education campaigns.

Ifeoma Nancy Nzelu, Rabi Rebecca Mairabo, Esther Godiya Haruna, Hassana Issac Dunka, Ikyereve Denen, Nana Hauwa Moru, Te (…)2026-10-14
📄 medicine

Association Between Oxybutynin Exposure and Psychiatric and Neurodevelopmental Outcomes in Children with Spina Bifida and Neurogenic Bladder: A Retrospective Cohort Study

This retrospective cohort study of children with spina bifida and neurogenic bladder found that long-term oxybutynin exposure is significantly associated with increased risks of developing anxiety and scholastic disorders, suggesting a need for enhanced monitoring of psychiatric and learning-related symptoms during therapy.

Takayuki Fujii, Yui Noguchi, Nanami Harada, Hiroto Katami, Aya Tanaka2026-10-14