📄 Category

medicine

4090 papers

📄 medicine

Clinical Application of a Dual-Threshold Bolus Tracking Protocol in One-Stop Combined CT Angiography and Venography of the Lower Extremities: A Prospective Comparative Observational Study

This prospective comparative study demonstrates that a personalized dual-threshold bolus tracking protocol significantly improves venous image quality and diagnostic yield in one-stop lower extremity CTA-CTV compared to a fixed-delay approach, while maintaining equivalent arterial enhancement and radiation dose.

Qing-Peng Zhan, Shang-Ao Gong, Yu-Long Xie, Ting Wang, Hao Zhou, Chang-Zheng Shi2026-07-14
📄 medicine

Prevalence and characteristics of enamel hypomineralisation in permanent teeth among orthodontic patients aged 8 to 18 years: a retrospective study.

This retrospective study of 361 orthodontic patients aged 8 to 18 found that molar incisor hypomineralisation (MIH) has a 24.9% prevalence and is strongly associated with hypomineralisation in other permanent teeth and enamel hypoplasia, highlighting the need for early monitoring of non-index teeth in affected children.

Cung May Thai, Gwen Feenstra, David John Manton, Isabel Cristina Olegário, Clarissa Calil Bonifacio2026-07-14
📄 medicine

Chronic Illness and Impoverishment in Urban Bangladesh: Evidence from Household Income and Expenditure Survey 2022

Using 2022 Household Income and Expenditure Survey data, this study reveals that chronic illness and Out-of-Pocket healthcare spending in urban Bangladesh create a vicious cycle where households are significantly more likely to fall into poverty due to medical costs, while poverty simultaneously increases the risk of chronic illness.

Azima Begum, Muhammad Shahadat Hossain Siddiquee2026-07-14
📄 medicine

Antibiotic trajectories after cardiopulmonary bypass and in-hospital mortality across critical care databases

This multi-database cohort study demonstrates that specific postoperative antibiotic trajectories, particularly persistent broad-spectrum therapy and late escalation, are reproducible prognostic markers of increased in-hospital mortality in cardiopulmonary bypass patients, outperforming conventional binary exposure definitions.

Ding Zhang, Ru-qin Yi, Wei Chen, Cheng-en Li, Zhi-rong Zhang, Ying-ying Shen, Zhao-kun Fan2026-07-14
📄 medicine

Joint Associations of Anthropometric Indices and the Cholesterol– High‑Density Lipoprotein–Glucose Index with Collateral Circulation Formation in Patients with Chronic Total Occlusion of Coronary Arteries: A Cross‑Sectional Study

This cross-sectional study of 841 patients with chronic total occlusion reveals that cholesterol–high-density lipoprotein–glucose (CHG) modified anthropometric indices, particularly CHG-ABSI and CHG-WWI, are strongly and independently associated with poor collateral circulation formation, outperforming the CHG index alone in identifying patients with an adverse metabolic-adiposity phenotype.

Xueyu Lv, Junqi Yu, Xiaoyan Lu, Zhihang Du, Dan Li2026-07-14
📄 medicine

Molecular spectrum and genotype-phenotype correlations in Romanian patients with neurofibromatosis type 1

This study characterizes the molecular spectrum and genotype-phenotype correlations in 162 Romanian patients with neurofibromatosis type 1, revealing 17 novel variants, significant phenotypic variability even among individuals with identical genotypes, and the importance of comprehensive genomic testing for identifying dual diagnoses and guiding multidisciplinary surveillance.

Teodora Toc, Nicoleta Ioana Andreescu, Catalin Vasile Munteanu, Iulia-Elena Simina, Florina Stoica, Aurora Alexandra Jur (…)2026-07-14
📄 medicine

Feasibility of a primary care-based adapted physical activity program for older adults with chronic conditions: the CAPA-CITY 70 pilot study

The CAPA-CITY 70 pilot study demonstrates that a primary care-based, supervised adapted physical activity program is feasible and highly acceptable for community-dwelling adults aged 70 and older with chronic conditions, achieving high completion and adherence rates while supporting the need for larger controlled trials to assess long-term effectiveness.

Emile Escourrou, Thomas Richaud, Aurore Palmaro, Bruno Chicoulaa, Sandrine Andrieu, Stéphane Oustric2026-07-14
📄 medicine

Impact of catheter-induced flow compromise on the presence of multiple ischemic lesions in endovascular treatment of posterior circulation aneurysms: a two-center retrospective study

This two-center retrospective study of 108 patients demonstrates that catheter-induced flow compromise, driven primarily by vertebral artery tortuosity and including both complete wedges and incomplete flow stasis, is a strong independent predictor of multiple new ischemic lesions following endovascular treatment of posterior circulation aneurysms, underscoring the need for rigorous preoperative anatomical assessment and intraprocedural risk-avoidance strategies.

Nagatsuki Tomura, Kento Asakura, Tomoyuki Tsumoto, Fukutaro Ohgaki, Jo Sasame, Shigeo Matsunaga, Takashi Shuto2026-07-14
📄 medicine

Emergency Presentations and Predictors of Adverse Outcomes in Systemic Lupus Erythematosus: A Retrospective Cohort Study

This retrospective cohort study of 50 SLE patients presenting to the emergency department found that while immunological markers and complement depletion are associated with severe disease, the clinical severity of the presentation itself is the strongest predictor of ICU admission and mortality.

Emad Elshebiny, Ahmed Shaltoot, Amr Hussien Ahmed Zaki, Enas Sobhy Zahran, Athar Fekry Lasheen, Mohammed Khalil, Mohamed (…)2026-07-14