📄 medicine

Effect of Low-flow CO₂ Insufflation on Hemodynamics in Gynecological Laparoscopic Surgery: A USCOM-based Randomized Controlled Trial

This randomized controlled trial demonstrates that using a low CO₂ insufflation rate of 1 L/min, compared to the standard 5 L/min, significantly better preserves cardiac output and stroke volume while reducing systemic vascular resistance during gynecological laparoscopic surgery without compromising surgical efficiency.

Rui Liu, Yingcai Song, Zhiqiang Liu, Jiang Li2026-07-14
📄 medicine

Mini-incision surgery combined with a self-made Kirschner wire micro automatic retractor for carpal tunnel syndrome: a retrospective clinical study

This retrospective study of 67 patients demonstrates that palmar mini-incision surgery utilizing a self-made Kirschner wire micro automatic retractor is a safe, minimally invasive, and highly effective treatment for moderate to severe carpal tunnel syndrome, achieving a 95.2% excellent-to-good functional outcome rate.

Xian-wei He, Yingkai Zhang, Bing-qing Huang, Liang-sheng Wang, Wei-wei Ye, Rong-bo Wu, Guo-ping Cai2026-07-14
📄 medicine

Prevalence of Impaired Diffusing Capacity of Lungs for Carbon monoxide in Smokers with normal spirometry

This cross-sectional study of 39 adult male smokers with normal spirometry reveals a high prevalence (72.5%) of impaired diffusing capacity (DLCO), suggesting that combining DLCO assessment with age, smoking history, and FEF25–75 metrics can significantly improve early detection of pre-COPD beyond traditional spirometry alone.

Rohita S, Aruna Shanmuganathan, Chitra kumar, Sam Selva Shruthi, Ramadevi Santhanakumar2026-07-14
📄 medicine

Value of Immune-Inflammatory Markers Derived from complete blood count in Umbilical Cord for the Early Diagnosis of Early-Onset Sepsis Complicated with Purulent Meningitis in Preterm Infants: a single-center prospective study

This prospective study demonstrates that the monocyte-to-lymphocyte ratio (MLR) derived from umbilical cord blood complete blood counts serves as a noninvasive, cost-effective, and relatively accurate early diagnostic marker for predicting purulent meningitis in preterm infants with early-onset sepsis.

Zongli Chen, Keyong Luo2026-07-14
📄 medicine

Measuring AI Readiness in Health Professions Education: Development and Validation of the AI Competence and Preparedness Evaluation Resource (AICPER)

This study presents the development and rigorous psychometric validation of the AICPER, a multidimensional instrument designed to assess health professions trainees' perceptions of AI across functional, ethical, and educational domains, demonstrating strong reliability and structural validity across nursing, pharmacy, and public health programs.

Divya Kewalramani, Oluwaseun J. Adeyemi, Stuti Shah, Justin L. Benton, Dylan R. Nieman, Advaith Bongu, Nell Maloney Pate (…)2026-07-14
📄 medicine

Fostering Hope through Exergaming in Hospitalized Children with Hematological Malignancies: A Multi-Perspective Qualitative Study Guided by Snyder’s Hope Theory

This qualitative phenomenological study, guided by Snyder's Hope Theory, reveals that exergaming fosters hope in hospitalized children with hematological malignancies by enabling them to reframe hospitalization into attainable goals, construct feasible pathways within clinical constraints, and activate a distributed sense of agency through the collaborative efforts of children, caregivers, and healthcare professionals.

Yujie Hang, Yulu Ren, Zhizhi Jin, Shenjie Chen, Jiayi Deng, Yanni Guo, Xiaonan Wu, Runping Wang, Chunmei Zhang2026-07-14
📄 medicine

Integrated UPLC-MS/MS Metabolomics Reveals Novel Metabolic Markers for Type I Endometrial Carcinogenesis in Clinical Samples

This study utilized integrated UPLC-MS/MS metabolomics and transcriptomics on paired clinical samples to identify 436 differential metabolites and key pathways, such as ferroptosis and ABC transporters, that characterize Type I endometrial carcinogenesis and offer novel biomarkers for diagnosis and treatment.

Yachai Li, Jiarui Mi, Peixuan Wang, Meng Li, Liwei Yan, Yuanmei Deng2026-07-14
📄 medicine

Wealth-Related Inequity in the Co-occurrence of Obesity Hypertension and Diabetes in India from a Concentration Index Analysis of NFHS-6 2023-24

This study analyzes NFHS-6 (2023–24) data to reveal that while obesity and diabetes in India are strongly concentrated among the urban wealthy, hypertension is more equally distributed, suggesting a need for targeted fiscal interventions for metabolic risks and universal screening for blood pressure control.

Arul Murugan, Shobana S2026-07-14
📄 medicine

A Cross-Sectional study to assess the Attitudes of Health Care Providers (HCPs) about Maternal Health Promotion: Insights from Sultanpur City

This cross-sectional study of 300 Anganwadi Workers in Sultanpur City reveals that while the majority hold positive attitudes toward maternal health promotion, significant disparities exist based on rural versus urban postings and work settings, highlighting the urgent need for targeted capacity-building interventions to ensure equitable service delivery.

Sneha Srivastava, Ritu K. Sureka2026-07-14
📄 medicine

Guben Antai Decoction Inhibits M1 Macrophage Polarization via the NF-κB/HIF-1α Pathway: A Mechanistic Study on the Treatment of Recurrent Spontaneous Abortion

This study demonstrates that Guben Antai Decoction (GBAT) treats recurrent spontaneous abortion by inhibiting M1 macrophage polarization and suppressing the NF-κB/HIF-1α signaling pathway, thereby restoring trophoblast migration and invasion capabilities.

Xin Du, Bingyao Yang, Xin Zhang, Xuebing Li, Qingqing Wang, Qiqi Fu, Guilin Li, Dong Wu, Chunxia Wang, Yongwei Li2026-07-14