📄 medicine

Intra- and inter-rater reliability of spinopelvic measurements in functional positions for total hip arthroplasty

This study demonstrates that Spino-Pelvic Tilt and Sacral Slope offer superior intra- and inter-rater reliability compared to Anterior Pelvic Plane tilt for assessing pelvic tilt in functional positions during total hip arthroplasty planning, leading to a recommendation to prioritize the former two measurements.

Dirk van Bavel, Isaac Rhee, Andrew Kurmis, Ryan Quarrington, Lucian Bogdan soloman2026-07-14
📄 medicine

A Comparison of Pathogen Culture and Metagenomic Next-Generation Sequencing in Periprosthetic Joint Infections and Implications for Empirical Antibiotic Selection: An 9-Year Retrospective Study

This nine-year retrospective study of 407 periprosthetic joint infection patients demonstrates that metagenomic next-generation sequencing (mNGS) significantly outperforms traditional culture in detection rates and identifying mixed infections, thereby enabling more precise empirical antibiotic selection through the integration of mNGS data with susceptibility-based predictive models.

Haibo Sun, Tao Zhang, Zheng Su, Rui Zhang, Xianli Hu, Zhen Pang, Yao Luo, Chen Zhu2026-07-14
📄 medicine

Spatiotemporal hotspots of neonatal and child mortality in Nyeri County, Kenya, 2018–2025

This retrospective spatio-temporal analysis of Nyeri County, Kenya (2018–2025), reveals that under-five mortality is significantly clustered in specific wards, particularly among neonates, with persistent hotspots in Ruring'u, Kiganjo/Mathari, and Rware that warrant prioritized public health interventions.

Aloise Gikunda, Yvonne Opanga, Nelson Muriu, Meshack Ndirangu, Anthony Waruru, Anne Gitimu, Paul Maleya, Brian Okada, Jo (…)2026-07-14
📄 medicine

Dynamic CEA trajectories predict survival for non-metastatic colon cancer: development and validation of a combined prognostic model

This study developed and validated a combined prognostic model incorporating dynamic CEA trajectory classifications, demonstrating that integrating longitudinal CEA monitoring with clinicopathological factors significantly improves survival prediction for patients with non-metastatic colon cancer compared to traditional static models.

Yiyun Hu, Yimin Wu, Junbo Yuan, Dening Ma, Shunv Cai2026-07-14
📄 medicine

A Longitudinal Study on Predicting Quality of Life in T3 Stage Radiotherapy Patients Based on Ensemble Learning and SHAP Interpretation

This longitudinal study developed and validated a robust Stacking ensemble learning model with SHAP interpretation to accurately predict the quality of life of patients with abdominal malignant tumors three months after radiotherapy, identifying key modifiable determinants and their clinical thresholds to guide precision rehabilitation interventions.

Yanze Shi, Jiayin Liu, Yu Tian, Wei Zheng, Hui Li2026-07-13
📄 medicine

Postoperative C-reactive protein for detecting anastomotic leakage after elective laparoscopic colorectal resection: a prospective cohort study

This prospective cohort study demonstrates that a postoperative day 4 C-reactive protein level above 137.3 mg/L is a highly sensitive and specific marker for detecting anastomotic leakage after elective laparoscopic colorectal resection, outperforming trajectory-based metrics but showing reduced accuracy in patients with protective diverting stomas.

Diego Gianetti Bahamonde, Francisco Rivera Roa, Fabio Paoletto, Manuel Lizana Corvera2026-07-13
📄 medicine

Readiness of Medical Students to Use Artificial Intelligence in Medical Education: A Cross-sectional Study

This cross-sectional study of 225 medical students at Izmir Katip Celebi University reveals a moderate level of readiness to use artificial intelligence in medical education, characterized by neutral-to-positive attitudes and a significant need for structured training to enhance cognitive, skill-based, foresight, and ethical competencies.

Seçil Özçiftçi, Emre Yörük, İris Can, Mustafa Tügün, Melih Yüksek, Betül Yüksek, Mustafa Agah Tekindal2026-07-13✓ Author reviewed
📄 medicine

Neural Inflexibility and Temporal Fragmentation of Sensory-Attention Networks in Migraine with Aura: A Hidden Markov Model Study

This study utilizes Hidden Markov Modeling on resting-state fMRI data to reveal that interictal migraine with aura is characterized by temporal inflexibility and fragmentation of sensory-attention networks, specifically marked by reduced dwell time in sensory-attention coupling states and a shift toward rigid, high-demand attentional control configurations that correlate with increased disease disability.

Yi-Ming Li, Chun-Yang Xu, Wen-Li Tan, Shu-Hui Gong, Jia-Xin Yu, Zheng Tu, Hui-Hui Xu, Yu Wu, Yu-Chan Yang2026-07-13
📄 medicine

Comparison Of Surgical Microscope-Assisted Gum Drop Surgical Technique Versus Conventional Gum Drop Surgical Technique Using T-PRF in the Management of Gingival Recession: A Randomized Controlled Clinical Study

This randomized controlled clinical study demonstrates that the surgical microscope-assisted Gum Drop Technique using T-PRF offers superior early stabilization, enhanced precision, and improved patient comfort compared to the conventional technique for managing Miller's Class I and II gingival recession, while both methods achieve comparable long-term root coverage outcomes.

saranya Mohan, vijayalakshmi R, LAKSHMI PRIYA K, BURNICE NALINAKUMARI, JAIDEEP MAHENDRA2026-07-13