📄 medicine

Facilitators and barriers influencing the provision of prehospital care following road traffic accidents in Rwanda: A Descriptive qualitative study

This descriptive qualitative study of 20 prehospital providers in Rwanda identifies key facilitators such as training, leadership, and community collaboration, alongside significant barriers including resource shortages, traffic congestion, and weak inter-agency coordination, which collectively influence the quality and timeliness of emergency care following road traffic accidents.

Liberatha Rumagihwa, Priscille Musabirema, Gerard Urimubenshi, Isabel Coetzee-Prinsloo, Jean Claude Byiringiro2026-07-13
📄 medicine

Development of a Novel Biocompatible Pipette for Cumulus–Oocyte Complex Transfer: An Experimental and Functional Evaluation Using HSA and MEA

This study demonstrates that a novel medical-grade silicone pipette designed to minimize shear stress is biocompatible and functionally effective for cumulus–oocyte complex transfer, as evidenced by high sperm motility, normal embryo development rates, and improved handling characteristics in Human Sperm and Mouse Embryo Assays.

Fatemeh Dehghanpour, Davoud Javid Mehr2026-07-13
📄 medicine

A foundation-model-powered AI system with post-read alerts and concurrent assistance improves gastric biopsy diagnosis across 29 pathological categories

This study presents a data-efficient, foundation-model-powered AI system capable of classifying 29 gastric biopsy categories that, when deployed through both concurrent assistance and post-read alert paradigms, significantly improves diagnostic sensitivity for malignancy and metaplasia while identifying missed cases in routine practice.

Chi-Chung Chen, Shih-Chiang Huang, Tu-Yung Chang, Chen-Lin Chi, Huei-Chieh Chuang, Jui Lan, Pei-Hua Chang, Cheng-Hsi Lin (…)2026-07-13
📄 medicine

Vessel-specific quantitative plaque characteristics on coronary CT angiography for prediction of FFR-defined myocardial ischemia

This study demonstrates that vessel-specific quantitative plaque characteristics derived from coronary CT angiography provide incremental predictive value for FFR-defined myocardial ischemia beyond stenosis severity, with particularly strong improvements in discrimination for the left anterior descending and right coronary arteries.

Shuang Li, Tian Ma, Anqi Yang, Yinghao Xu, Yi He2026-07-13
📄 medicine

Clinical workload dimensions, multidimensional physician well-being, and turnover intention across primary healthcare facilities and hospitals in China: a cross-sectional study

This cross-sectional study of 1,324 Chinese physicians reveals that distinct clinical workload dimensions, including long working hours, frequent night shifts, and high outpatient volumes, are significantly associated with diminished multidimensional well-being and increased turnover intention, highlighting the need for differentiated workload management strategies beyond total hours to support workforce retention.

Huixian Zheng, Mingyue Li, Haoqing Tang, Yuxun Zhou, Xiaoyun Liu2026-07-13
📄 medicine

Electronic Health Records and Interprofessional Collaboration: A Constructivist Grounded Theory of Information Exchange in Inpatient Care

Through a constructivist grounded theory study of inpatient care, this paper reveals that Electronic Health Records often function more as profession-specific repositories than as effective interprofessional coordination tools, necessitating informal workarounds to bridge the gap between system design and the collaborative information quality needs of clinical teams.

Oluwakemi Olufunmilayo Oluwole, Amanda McIntyre, Kristen A. Bishop, Mark Goldszmidt2026-07-13
📄 medicine

Segmental Absence of Intestinal Musculature and Its Mimics in Adult Lower Gastrointestinal Perforation: A Review of 100 Cases

This study reviews 100 adult lower gastrointestinal perforation cases to highlight the diagnostic challenges and specific histopathological criteria required to accurately identify the rare condition of segmental absence of intestinal musculature (SAIM) and distinguish it from mimics like diverticular disease and ischemia.

Tomohiro Takeda, Sayaka Yuzawa, Manami Hayashi, Shoichiro Mizukami, Yuki Kamikokura, Masahide Otani, Mizuho Ohara, Chika (…)2026-07-13
📄 medicine

Cardiometabolic–Resting-State Functional Connectivity Associations Differ by Age and Menopausal Status in Middle-Aged Females

This study demonstrates that menopause status significantly differentiates how cardiometabolic risk factors, such as systolic blood pressure and total cholesterol, relate to resting-state functional connectivity patterns in middle-aged females, with specific associations varying by menopausal stage despite neither pattern predicting spatial memory performance.

Julia Kearley, Charana Rajagopal, Sophia LoParco, Millie R. Bhaskara, Lucina Q. Uddin, Bratislav Misic, Gillian Einstein (…)2026-07-13
📄 medicine

Diabetes and pregnancy outcomes in retrograde ejaculation by sperm source and aetiology: an exploratory ICSI study

This exploratory multicentre study found that diabetes is an independent predictor of poorer ICSI outcomes in patients with retrograde ejaculation, while numerical trends suggesting superior results with testicular versus ejaculated sperm require confirmation through larger prospective studies.

Haitian Ding, Ruijun Liu, Sana Atta, Yuqin Hu, Aylla Qayyum, Dongdong Tang, Hao Geng, Ping Zhou, Zhaolian Wei, Yuping Xu (…)2026-07-13
📄 medicine

Replication Protein A in Cancer: A Pan-Cancer Analysis Focusing on Lower-Grade Glioma and Liver Hepatocellular Carcinoma

This pan-cancer analysis reveals that overexpression of Replication Protein A (RPA) genes is associated with poor prognosis, an immunosuppressive tumor microenvironment, and weak immunotherapeutic response in Lower-Grade Glioma and Liver Hepatocellular Carcinoma, while simultaneously indicating susceptibility to targeted drugs like doxorubicin, thus positioning RPA as a promising prognostic and therapeutic biomarker for these cancers.

Ravi Bhushan, Arunima Dhurve, Prachi Gupta, Shishir K Gupta, Prabhaker Yadav2026-07-13