📄 Category

medicine

13870 papers

📄 medicine

Development and in vivo characterization of the first peptide-based 99mTc-Nitrido-radiopharmaceuticals for FAP-targeted SPECT imaging

This study successfully developed and characterized the first peptide-based 99mTc-nitrido radiopharmaceuticals targeting Fibroblast Activation Protein (FAP), demonstrating that the choice of bisphosphinoamine ligand significantly influences biological profiles, with the [99mTc][Tc(N)PNP3]-cysFAP compound showing the most favorable in vivo performance for SPECT imaging of FAP-positive tumors.

Janke Kleynhans, Nicola Salvarese, Carolina Gobbi, CM. Deroose, Frederik Cleeren, Cristina Bolzati2026-10-14
📄 medicine

A Systematic Literature Review of Large Language Models in Clinical Triage from Risk Stratification to Human Escalation

This systematic and bibliometric review synthesizes 89 studies published between 2022 and 2026 to analyze the application of Large Language Models in clinical triage, evaluating their adaptation strategies, safety mechanisms, and performance metrics while proposing a new 5-dimension framework to guide their safe translation into emergency care settings.

Manpreet Singh, Muhammad Zeeshan, Abhijeet Mukkawar, Rahul Joshi, Asha Pandit Ghodake, Hanamant Bhagwan Sale2026-10-14
📄 medicine

Concentration Levels and Health Risk Assessment of Carcinogenic and Non-Carcinogenic Heavy Metals in Chicken Tissues Marketed in Nsukka Metropolis, Nigeria

This study found that while heavy metal concentrations in chicken tissues from Nsukka, Nigeria, pose negligible non-carcinogenic risks, the estimated cancer risk values for lead, chromium, cadmium, and nickel significantly exceed WHO safety limits, indicating a potential public health hazard from prolonged consumption.

O. J. Ogbueli, I.M. Ezenwa, U. Madu, A. O Iwuchika, S.A. Ayodeji, G.U. Nwankwo, C.V. Asogwa, C.P. Arinze, M.U. Agwu2026-10-14
📄 medicine

Perceived Realism of 3D-Printed Teeth, Extracted Human Teeth and Clinical Patient Cases in Endodontic Training: A Within-Subject Study

This study found that while extracted human teeth offer the highest perceived realism compared to clinical cases for endodontic training, current 3D-printed models serve as valuable standardized and ethical adjuncts despite their lower fidelity, particularly in procedures requiring tactile feedback.

Elhassan Hassanein, Sarah Krajan, Mohamed Nagy, Izzeddin Abdi2026-10-14
📄 medicine

Three-year persistence and clearance patterns of high-risk HPV genotype groups among women in Chirchik, Uzbekistan: A secondary analysis of a pilot screening study

This secondary analysis of a pilot screening study in Chirchik, Uzbekistan, characterizes the baseline distribution and 3-year persistence patterns of high-risk HPV genotype groups among local women, revealing that single infections predominate, HPV16 is the most prevalent genotype, and clearance rates for HPV16 show no statistically significant difference based on co-infection status.

Dilobar Utkirovna Abdumalikova2026-10-14
📄 medicine

Wearable Single-Lead ECG Detects Fine-Grained Structural Heart Disease Through Echo-Report Supervision

The AnyECG-Echo framework leverages wearable single-lead ECGs and echo-report supervision to accurately detect 13 fine-grained structural heart disease subtypes across diverse populations, offering a scalable, interpretable solution for early screening that correlates with key physiological metrics.

Shenda Hong, Chenyang He, Qinghao Zhao, Shun Huang, Jun Li, Gongzheng Tang, Hao Zhang, Tong Liu, Zhengkai Xue, Jian Liu (…)2026-10-14
📄 medicine

Assessment of the Physical Development of Children in Transbaikal Territory, Russian Federation

This retrospective study of 972 children with bronchial asthma in the Transbaikal Territory (2017–2024) reveals that while nearly half maintain normal weight, a significant portion suffers from malnutrition or obesity, with the latter affecting one-third of patients and potentially contributing to uncontrolled asthma, thus highlighting the need for individualized rehabilitation programs.

Artem Babkin, Irina Bogomolova2026-10-14
📄 medicine

Candidate Pharmacogenomic and HLA Risk Alleles for Drug-Induced Liver Injury in Vietnamese Cancer Patients: A Pre-Specified Case-Control Study

This pre-specified case-control study of 101 Vietnamese cancer patients with drug-induced liver injury and 101 matched controls found no significant associations between DILI and candidate pharmacogenomic variants, HLA alleles, or CPIC actionable-allele burdens, suggesting that larger collaborative studies are required to detect moderate genetic risk factors in this population.

Nguyen Thai, TT Hang, Huyen Tran, Hien Tran, Huyen Dao, To Pham, Thinh Nguyen, Vinh Duong, Huong Vuong, Vu Mai, Nam Vo (…)2026-10-14
📄 medicine

Assessment of Heat Stress in Iranian Industries and Temporal Trends over the Last Two Decades: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis of 43 studies reveals that occupational heat stress in Iran is substantial, with pooled mean Wet Bulb Globe Temperature (WBGT) levels significantly higher in roofed environments and showing a concerning upward trend over the past two decades in open-air settings, particularly affecting workers in the steel and date-harvesting industries.

Azam Saffar, Maryam Feiz-Arefi, Atefeh Mohamadinejad, Parvin Sepehr2026-10-14