📄 Category

medicine

4098 papers

📄 medicine

CHA₂DS₂-VASc Score for Pre-Procedural Prediction of Contrast-Associated Acute Kidney Injury After Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction: A Head-to-Head Comparison with the Mehran Score

In a prospective cohort of STEMI patients undergoing primary PCI, the pre-procedural CHA₂DS₂-VASc score demonstrated comparable predictive accuracy for contrast-associated acute kidney injury to the post-procedural Mehran score, offering a practical, bedside alternative for risk stratification in resource-limited settings where laboratory data is unavailable prior to the procedure.

Sushant Kharel, Birat Krishna Timalsena, Amrit Bogati, Mohammed Sajjad Safi, Pratik Thapa, Rahul Yadav, Vijay Ghimire, C (…)2026-07-12
📄 medicine

Patient and Physician Preferences for Treatment in Advanced Renal Cell Carcinoma in Asia-Pacific (PEAR)- A Discrete Choice Experiment

This discrete choice experiment involving patients and physicians in the Asia-Pacific region reveals that while both groups prioritize overall survival, complete response, and duration of response, patients are significantly more risk-averse regarding treatment side effects like pneumonitis compared to physicians, underscoring the need for shared decision-making that integrates these divergent benefit-risk trade-offs.

Alison Zhang, Niara Oliveira, Bryan Li, Inkeun Park, Miso Kim, Sharon Yu Lin Chua, Anilda Anthony D’Souza, Sameer Gokhal (…)2026-07-12
📄 medicine

Mechanisms of Attainment Gaps in UK Surgical Training: A National Qualitative Study of Trainee Experiences

This national qualitative study reveals that attainment gaps in UK surgical training stem from the interaction between organizational barriers and unequal access to social, financial, and cultural capital, which disproportionately affects female, ethnically minoritized, and gateway pathway trainees, thereby necessitating structural reforms alongside targeted support to ensure equitable progression.

Nicholas Uren, Gayatri Tadikamalla, Ahmad Elmansouri, Benjamin Preston, Judith Cave, Sally Curtis2026-07-12
📄 medicine

Patient-Reported Outcomes and Sexual Function After Nerve-Sparing Pelvic and Para-Aortic Lymphadenectomy With or Without Suprarenal Extension in Presumed Early-Stage Endometrial Cancer

In patients with presumed early-stage endometrial cancer, nerve-sparing pelvic and infrarenal lymphadenectomy does not significantly impair long-term quality of life or sexual function, whereas suprarenal extension is associated with worse outcomes, and extensive lymphovascular space invasion serves as a strong predictor of nodal metastasis.

Valentina Auletta, Lydia Kirstan, Angela Kather, Davit Bokhua, Tobias Franiel, Ingo Bernarnd Runnebaum2026-07-12
📄 medicine

Association between the blood urea nitrogen to albumin ratio and all-cause mortality in critically ill patients with non-traumatic subarachnoid hemorrhage: a multicenter retrospective study and machine learning with external validation

This multicenter retrospective study with external validation and machine learning analysis demonstrates that a higher blood urea nitrogen to albumin ratio (BAR) is an independent predictor of increased all-cause mortality at 30, 90, and 365 days in critically ill patients with non-traumatic subarachnoid hemorrhage.

Liang Liu, Zhilei Huang, Binbin Gui, Lin Xu, Wei Zhang, Yansong Liu, Haowei Luo, Xiangtong Zhang2026-07-12
📄 medicine

Joint Associations of Serum Vitamin D and Physical Activity with Bone Mineral Density and Body Composition in U.S. Adolescents: A Cross-Sectional Study Based on NHANES 2011-2018

This cross-sectional study of U.S. adolescents using NHANES 2011–2018 data reveals that higher serum vitamin D levels are positively associated with better bone mineral density and lean mass while negatively linked to visceral fat, with these beneficial effects being significantly stronger among physically active individuals.

Bingrong Tang¹, Chunxiang Yan¹, Han Xia¹, Min Wang¹, Ji Wu², Xiaobing Feng¹2026-07-12
📄 medicine

Epidemiological Characteristics of Emergency Medical Service Calls in a Large Chinese City: A Retrospective Analysis of 191,730 Prehospital Dispatches in 2024

This retrospective analysis of 191,730 EMS dispatches in a large Chinese city during 2024 reveals that emergency demand is heavily concentrated among older adults and driven by injuries and time-sensitive medical conditions with distinct diurnal and age-related patterns, highlighting the need for optimized staffing, targeted prevention strategies, and the diversion of low-acuity non-emergency transport to dedicated services to improve resource efficiency.

Hao Zou, Guanguan Luo, Cheng Jiang, Jing Wan, Yong Zou, Jian Xia2026-07-11
📄 medicine

Burden, Geographic Variation, and Determinants of High-Risk Fertility Behavior Among Women in Bangladesh: Insights from the BDHS 2022 

Utilizing 2022 BDHS data, this study reveals that approximately 23% of married women in Bangladesh engage in single high-risk fertility behavior and 4% in multiple high-risk behaviors, with significant geographic disparities and distinct socioeconomic determinants such as education, healthcare access, and rural residence influencing these outcomes.

Md Rafi Hasan, Dalia Akter, Md Sabbir Hossain, Md Jamal Uddin2026-07-10
📄 medicine

An interpretable machine learning model to predict postoperative acute kidney injury following pancreatic surgery

This study developed and validated an interpretable Random Forest model using five readily available preoperative and intraoperative variables to accurately predict post-pancreatectomy acute kidney injury, with SHAP analysis identifying intraoperative blood loss as the strongest risk factor.

Zhou Chen, Hanchen Wu, Yifan Wang, Jun Zhang, Bin Song, Zhiyong Guo, Qi Bian2026-07-10