📄 Category

medicine

4098 papers

📄 medicine

Structural and physeal integrity, not surgical timing, determines functional outcome after delayed open reduction and Kirschner-wire fixation of neglected paediatric lateral humeral condyle fractures: an ambispective clinical, radiological and MRI study

This ambispective study demonstrates that functional outcomes following delayed open reduction and K-wire fixation of neglected paediatric lateral humeral condyle fractures are determined by the structural and physeal integrity of the elbow rather than the duration of injury neglect.

Rahul Rai, Shubham Srivastava, Shivam Sinha, Amit Rastogi, Pramod Kumar Singh, Soumya Ranjan Nayak, Sushil Gandhi, Kajal (…)2026-07-10
📄 medicine

Human papillomavirus-associated immune profile of the tumor microenvironment in laryngeal squamous cell carcinoma: a Tunisian cohort study

This Tunisian cohort study reveals that laryngeal squamous cell carcinoma cases positive for high-risk HPV exhibit a distinct tumor microenvironment characterized by significantly increased infiltration of CD8⁺ T cells, FOXP3⁺ regulatory T cells, and tumor-associated macrophages compared to HPV-negative cases.

Nehla Mokni Baizig, Salma Kamoun, Yosr Zenzri, Alia Methnani, Rim Abidi, Yoldz Houcine, Maha Driss2026-07-10
📄 medicine

An Automated Deep Learning Software Tool for Assessing Aortic Remodeling in Aortic Dissection

This study presents a proof-of-concept automated deep learning pipeline that demonstrates excellent agreement with manual measurements for assessing aortic remodeling in patients undergoing frozen elephant trunk repair, offering a scalable solution to overcome the labor-intensive limitations of current CT-based analysis.

Yu Nakano, Ikki Kojima, Masaki Kano, Toshiki Fujiyoshi, Yusuke Shimahara2026-07-10
📄 medicine

Effect of a Dual-Track Management Model on the Quality of SBAR Handoffs Among Junior ICU Nurses: A Quasi-Experimental Study

A quasi-experimental study in a Chinese tertiary hospital demonstrates that a dual-track management model combining empowerment and supervision significantly improved the quality, safety, and reliability of SBAR handoffs among junior ICU nurses while enhancing their self-efficacy and collaboration.

Meixia Xiao, Xiaoyan Li, Jiajun Wu, Ziyi Huang, Xiaoming Qiao, Qin Xiong2026-07-10
📄 medicine

Association of Lipoprotein(a) With SYNTAX Score in Young Adults Presenting with Acute Coronary Syndrome: A Cross-Sectional Study

This cross-sectional study of 55 young adults with acute coronary syndrome at AIIMS Rishikesh demonstrates a significant positive association between elevated Lipoprotein(a) levels and increased coronary angiographic severity as measured by the SYNTAX score, suggesting Lp(a) is a valuable marker for risk stratification in premature coronary artery disease.

AKASH SWAIN, BARUN KUMAR, KANIKA KUKREJA, ADITYA AGARWAL, KISHAN MAVANI2026-07-10
📄 medicine

Polyphenols from Rhizopus oligosporus-fermented Amaranth Alleviate Insulin Resistance via IRS-1/PPARγ-Mediated GLUT4 Activation

Solid-state fermentation of amaranth with *Rhizopus oligosporus* significantly enriches its polyphenol content, which alleviates insulin resistance by activating the IRS-1/PPARγ-mediated GLUT4 pathway in both hepatocytes and adipocytes, offering a promising food-grade strategy for managing metabolic disorders.

Jingyuan Li, Jiayang Wang, Ting Ding, Yang Deng2026-07-10
📄 medicine

Agreement and device-specific calibration of a single-frequency and a multi-frequency segmental bioelectrical impedance analyzer against dual-energy X-ray absorptiometry for appendicular skeletal muscle mass: a two-center method-comparison study with external validation

This two-center study demonstrates that while single- and multi-frequency bioelectrical impedance analyzers exhibit systematic, device-specific biases compared to dual-energy X-ray absorptiometry, applying device-specific calibration equations significantly improves accuracy and low-muscle-mass classification in external validation, underscoring that BIA and DXA cannot be used interchangeably without adjustment.

Yifei Ouyang, Chang Su, Ziyi Liu, Huijun Wang2026-07-10
📄 medicine

Altered resting-state functional connectivity and network topology in early-stage Parkinson’s disease: associations with depressive symptoms

This study utilizes resting-state fMRI and graph theory analysis of PPMI data to demonstrate that early-stage Parkinson's disease is characterized by specific alterations in functional connectivity and network topology, particularly within the default mode network, which are significantly associated with depressive symptom severity.

Zahra Khandan Khadem-Reza, Mohammad Amin Shahram, Seyed Amin Ghaemmaghami, Alireza Montazerabadi, Mahtab Khajeh, Seyedeh (…)2026-07-10
📄 medicine

Rethinking anthropometric risk: non-linear associations between body indices and carotid plaque

This study of Lithuanian adults reveals that the associations between anthropometric indices (ABSI, BRI, and BMI) and carotid plaque prevalence are complex and non-linear, particularly in men, where lower index values did not consistently indicate lower cardiovascular risk and often coincided with higher metabolic abnormalities.

Ignas Badaras, Roma Puronaite, Egidija Rinkuniene, Vytautas Kasiulevicius, Jolita Badariene, Vilma Dzenkeviciute2026-07-10
📄 medicine

The Impact of Maternal Infection with Cytomegalovirus, Parvovirus B19, and Toxoplasma gondii on Fetal Thymus Size

This study demonstrates that maternal infections with cytomegalovirus, parvovirus B19, and Toxoplasma gondii are significantly associated with increased fetal thymus size, suggesting that thymic measurements could serve as a potential marker for assessing fetal infection status and immune system development.

Christina Marie Becker, Mareike Möllers, Moritz Danzer, Anna-Lena Kuper, Kathrin Oelmeier, Ralf Schmitz, Daniela Willy2026-07-10