📄 Category

medicine

13909 papers

📄 medicine

Immunosenescence shapes the inflammatory response to viral infection in vaccinated and unvaccinated patients

This study demonstrates that immunosenescence significantly shapes the inflammatory response to viral infection by altering neutrophil dynamics and cytokine levels in both vaccinated and unvaccinated patients, with the combination of the pan-immune-inflammation value (PIV) and specific cytokines serving as highly accurate predictors of infection status, particularly in individuals aged 65 and older.

Bartosz Kudlinski, Jagoda Kania, Magdalena Murkos, Jacek Zawadzki, Edyta Wawrzyniak-Gramacka, Barbara Morawin, Magdalena (…)2026-10-11
📄 medicine

Case Report: A novel de novo pathogenic variant in COL1A1 causing osteogenesis imperfecta (OI) in a Chinese girl

This case report describes the first identification of a novel de novo pathogenic variant (c.406G > T, p.Gly136Ter) in the COL1A1 gene causing osteogenesis imperfecta in a Chinese girl, highlighting the importance of genetic testing for diagnosing the condition in children with recurrent fractures even when typical extra-skeletal features are absent.

Xinfeng Wang, Wei Wang, Liangfu Xie, Bing E, Yuhuan Liu, Guibing Fu, Jiansheng Wang2026-10-11
📄 medicine

Effects of Eye–Hand Coordination Training in Immersive Virtual Reality Environments on Reaction Time and Tactical Effectiveness in Male Youth Handball Players: A Randomized Controlled Trial

This randomized controlled trial demonstrates that an 8-week immersive virtual reality hand–eye coordination training program significantly improves auditory and visual reaction times in male youth handball players, while also showing non-significant positive trends in tactical effectiveness and cognitive processing speed.

Xurxo Rivas, Paula Lorenzo Estévez, Adriana López Rodríguez, José María Cancela Carral2026-10-11
📄 medicine

Physical Activity, Muscle Phenotypes, and Functional Health Outcomes Among Middle-Aged and Older Chinese Adults: A Multi- wave Cohort Study Using CHARLS

This multi-wave cohort study of Chinese adults aged 50 and older reveals that while physical activity is more strongly linked to concurrent muscle strength than to future muscle abnormalities, low grip strength is a clearer predictor of subsequent functional decline and deteriorating self-rated health than low muscle mass.

Shiyuan Shao, Hongjuan Li2026-10-11
📄 medicine

Network Analysis of Return-to-Work Readiness and Self-Efficacy Among Breast Cancer Patients by Return-to-Work Status: A Cross-Sectional Study

This cross-sectional network analysis of 501 breast cancer patients in China reveals that while the overall structure of return-to-work self-efficacy networks does not significantly differ between those who have and have not returned to work, the specific central and bridge nodes vary by status, suggesting that vocational rehabilitation assessments should be tailored to emphasize readiness and stress coping before returning to work, and motivation and energy support after resuming employment.

Qiu Huo, Yunxia Pu, huizhuo Deng, Xianqiong Feng2026-10-11
📄 medicine

Association Between Screen Time Exposure and Autism Spectrum Disorder Like Symptoms in Al-Baha Region

This cross-sectional study in Al-Baha, Saudi Arabia, reveals a significant correlation between excessive smart device screen time and increased ASD-like symptoms, such as social isolation and emotional dysregulation, among children, underscoring the urgent need for parental education and public health interventions to manage screen exposure during critical developmental periods.

Syed Ikramul Hasan2026-10-11
📄 medicine

Primary Leiomyosarcoma of the Urinary Bladder in a Middle-Aged Woman: A Case Report with Review of Previously Published Cases

This case report describes a rare instance of primary bladder leiomyosarcoma in a 43-year-old woman presenting with a synchronous uterine mass that mimicked a gynecologic malignancy, highlighting the importance of combined surgical management and immunohistochemical differentiation to achieve a favorable pT1N0 outcome despite the tumor's high grade.

Kartik Kadia, Lalatendu Moharana, Lipsita Samantaray, Abinash Patnaik, Santosh Kumar Swain, Mohita Ray, Debabrata Ku Sab (…)2026-10-11
📄 medicine

Determinants of urinary tract infections among pregnant women in Gambo General Hospital, Ethiopia: a case-control study

This 2026 case-control study conducted at Gambo General Hospital, Ethiopia, identifies that urinary tract infections among pregnant women are significantly driven by preventable factors including first and second trimester status, grand multigravida history, prior catheterization, low water intake, improper genital hygiene, and sexual activity, underscoring the need for enhanced prenatal counseling and clinical protocols.

Duressa Shafi Ahmed, Kedir Ulu Buta, Gelata Wakjira Areda, Tolcha Dechasa Weyesa, Janka Gebru Desta, Olika Gizachew, Kem (…)2026-10-11