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Immunosenescence shapes the inflammatory response to viral infection in vaccinated and unvaccinated patients

This study demonstrates that immunosenescence significantly shapes the inflammatory response to viral infection by altering neutrophil dynamics and cytokine levels in both vaccinated and unvaccinated patients, with the combination of the pan-immune-inflammation value (PIV) and specific cytokines serving as highly accurate predictors of infection status, particularly in individuals aged 65 and older.

Original authors: Bartosz Kudlinski, Jagoda Kania, Magdalena Murkos, Jacek Zawadzki, Edyta Wawrzyniak-Gramacka, Barbara Morawin, Magdalena Wojciech, Agnieszka Zembron-Lacny

Published 2026-10-11
📖 1 min read☕ Coffee break read

Original authors: Bartosz Kudlinski, Jagoda Kania, Magdalena Murkos, Jacek Zawadzki, Edyta Wawrzyniak-Gramacka, Barbara Morawin, Magdalena Wojciech, Agnieszka Zembron-Lacny

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). ✨ This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

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