📄 medicine

Associations of Health Insurance with Guideline-Concordant Treatment and Overall Survival Among Women with Breast Cancer

This study of over 200,000 California women with breast cancer reveals that inadequate health insurance, particularly Medicaid and Medicare compared to private coverage, is significantly associated with lower adherence to guideline-concordant treatments and worse overall survival, highlighting persistent disparities even after the Affordable Care Act.

Tu C. Le, Ruixiao R. Wang, Candice A.M. Sauder, Qian Li, Mahnoor Wani, Ana I. Jacinto, Theresa H.M. Keegan2026-10-09
📄 medicine

Behavioral economics of cigarette and cannabis co-use: Validating cigarette and cannabis single and cross-commodity purchase tasks

This study validates hypothetical purchase tasks for assessing cigarette and cannabis co-use, finding that while the tasks generally demonstrate sound psychometric properties, co-users are less likely to provide systematic responses and cannabis-specific measures showed limited validity within the co-use subgroup alone.

Christine E Sheffer, Shuangshuang Xu, Anthony N. Nist, Jeffrey S. Stein, Roberta Freitas-Lemos, Allison N. Tegge2026-10-09
📄 medicine

Exploring Service Engagement among Youth in Concurrent Disorder Services: A Qualitative Study

This qualitative study of 20 youth in Toronto reveals that engagement in concurrent disorder services is a dynamic, multidimensional process shaped by relational approaches and readiness to change, underscoring the need for flexible, youth-centered interventions to support retention and progress.

Meaghen Quinlan-Davidson, Anna Bowers, Michele Peterson-Badali, Jori Jones, Jo L. Henderson2026-10-09
📄 medicine

Implementing the Digital Equity for Stroke Approach (DESA): A Qualitative Study of Multilevel Barriers and Facilitators to Equitable Telehealth Implementation in Safety-Net Settings

This qualitative study identifies multilevel barriers and facilitators to telehealth adoption in safety-net settings to guide the implementation of the Digital Equity for Stroke Approach (DESA), concluding that equitable implementation requires coordinated investments in policy, infrastructure, and workforce support beyond mere technology access.

Efekona Nuwere, Aliyah Howard-Rodriguez, Sunha Park, Moyouri Bhattacharjee, David Kaufman, Aimee Afable2026-10-09
📄 medicine

Methodological quality and clinical applicability of obesity-related disease risk prediction models: a systematic review and meta-analysis

This systematic review and meta-analysis of 24 studies reveals that while obesity-related disease prediction models demonstrate promising discriminatory performance, their clinical applicability is significantly hindered by common methodological flaws, a high risk of bias, and a critical lack of external validation.

Limin Wang, Mengfan Wang, Zhuo Chen, Chuanlin Cao, Yuxiang Ma, Mengyun Sui, Xiaohua Ying2026-10-09
📄 medicine

In vitro and in vivo antifungal effects and mechanism of Daphnetin against Candida albicans

This study demonstrates that Daphnetin (DAP) and its thermo-responsive gel effectively inhibit *Candida albicans* growth and biofilms both in vitro and in vivo by disrupting cell integrity, inducing oxidative stress, and showing low resistance potential, thereby offering a promising multi-target strategy for treating fungal infections.

Yuqin Guo, Xing Wang, Jiayi Gao, Junhong Fan, Shaohua Li, Xiaorui Shi, Zhengfang Yu, Zhiyan Zhou, Huiju Liu, Xuke Zheng (…)2026-10-09
📄 medicine

Perceived Discrimination Moderates The Relationship Between Childhood Adversities and Cognitive Performance In Mental Illness

This study utilizing the PRONIA cohort reveals that the relationship between childhood adversities and cognitive performance is heterogeneous across clinical groups (including psychosis and depression) and is significantly moderated by perceived discrimination, indicating that these associations vary depending on the specific clinical context and ongoing psychosocial stressors.

Lana Kambeitz-Ilankovic, Öznur Bastürk, Lotta-Katrin Pries, Millennia Chakraborty, David Popovic, Kelly Allot, Alexandra (…)2026-10-09
📄 medicine

The Convention on the Rights of Persons with Disabilities Adherence Scale (CRPDAS): Development and Psychometric Validation of a Clinician-Level Measure of Rights-Based Practice

This study presents the development and psychometric validation of the CRPD Adherence Scale (CRPDAS), a reliable two-factor self-report instrument designed to assess mental health professionals' adherence to the UN Convention on the Rights of Persons with Disabilities principles at the clinician level.

Yael Harari, Yael Mayer, Ido Lurie2026-10-09
📄 medicine

Lesbian Patients' Reflection of Societal Norms in Primary Care—A Qualitative Interview Study in Germany

This qualitative study of 21 lesbian patients in Germany reveals that while heteronormative assumptions and knowledge gaps create barriers in primary care, patients navigate these challenges through either protective concealment or affirmed identity orientations, underscoring the need for provider training, structural changes, and culturally humble communication to improve healthcare experiences.

Anna Sophia Wittenstein, Judith Stumm, Eric Blumenauer, Malte Radde, Sebastian Melz, Wolfram J. Herrmann2026-10-09