📄 medicine

Esophago-Pericardial Fistula Associated with a Sharp Foreign Body Presenting with Tension Pneumopericardium and Cardiac Arrest During Endoscopy: A Case Report

This case report describes a rare instance of cardiac arrest caused by tension pneumopericardium resulting from an esophago-pericardial fistula due to a sharp foreign body, which was successfully managed through emergent pericardiocentesis, endoscopic foreign body removal, and surgical intervention.

Mohammad Jafari, Rayeheh Shekl abadi, Parvin Bahrami, Azam teimouri, Alireza Nematollahi2026-07-10
📄 medicine

A service evaluation of restraint, seclusion and escalation in inpatient mental health care: a retrospective observational study in England

This retrospective observational study of over 41,000 incidents in English inpatient mental health services reveals that restrictive practices operate as a two-stage system where service configuration determines restraint frequency and ward-level context influences escalation to seclusion, suggesting that reduction strategies must target both incident rates and the processes governing escalation.

Ndukwe Walter Ugwuocha, Oladayo Bifarin, Chengeto Shoko, Simon Nielson, Alexander Challinor, Deborah Morgan, Andrew Jone (…)2026-07-10
📄 medicine

A nomogram to predict shoulder dystocia in patients during labor: a retrospective cohort study

This retrospective cohort study developed and validated a nomogram based on six independent predictors—estimated fetal weight >4000 g, abdominal circumference–head circumference difference ≥2.5 cm, gestational diabetes, maternal BMI >28 kg/m², short stature ≤150 cm, and prolonged second stage of labor—to effectively stratify the risk of shoulder dystocia during vaginal delivery.

Peiran Yang, Zhiyi Yang, Xiaojun Guo, Jun Yan, Yongfei Yue2026-07-10
📄 medicine

Early One-Cycle Post-Neoadjuvant Chemotherapy Volumetric and SER-based Changes on DCE-MRI: Timely Predictors of Response and Prognosis in Breast Cancer

This study demonstrates that early volumetric and signal enhancement ratio-based functional tumor volume reductions observed on DCE-MRI after just one cycle of neoadjuvant chemotherapy serve as superior predictors of clinical response and recurrence-free survival compared to traditional size-based metrics or later assessments in breast cancer patients.

Alisa Mohebbi, Mehrad Zare, Zahra Moradi, Afshin Mohammadi2026-07-10
📄 medicine

Repeated PEFR-defined probable respiratory sarcopenia and incident frailty among middle-aged and older Chinese adults: a longitudinal CHARLS study

This longitudinal study of Chinese adults found that experiencing probable respiratory sarcopenia at least once during follow-up is associated with an increased risk of developing incident frailty, suggesting that PEFR-based screening serves as a useful population-level signal for frailty risk despite non-monotonic patterns across repeated measurements.

Qi Wang, Yasuo Ding, Yanhua Xu, Hongmei Wang2026-07-10
📄 medicine

Concurrent Pneumocystis jirovecii pneumonia and Guillain-Barre syndrome after surgery and adjuvant chemoradiotherapy for stage IIIA lung adenocarcinoma: a case report and literature review

This case report describes a rare instance of concurrent Pneumocystis jirovecii pneumonia and Guillain-Barré syndrome in a lung cancer patient following chemoradiotherapy, emphasizing the critical need for early, multi-modal diagnostic assessment to distinguish overlapping infectious and immune-mediated complications from treatment-related toxicity.

Hai-Bo Cai, Hui-Bin Chen, Jing-Hui Wang, Wen-Yu Wu, Dong-Xin Tang2026-07-10
📄 medicine

Asymptomatic Giant Tubulocystic Retroperitoneal Lymphangioma with Significant Compression of the Ascending Colon: A Case Report

This case report describes a rare instance of a giant, asymptomatic tubulocystic retroperitoneal lymphangioma in a 47-year-old woman that was successfully treated with complete surgical excision despite significant mass effect on the ascending colon, highlighting the importance of considering intervention for large cystic lesions even in the absence of symptoms.

Qi Xie, Xiao Xu2026-07-10
📄 medicine

Comparative Analysis of MMP-1 and α-SMA Expression in Ventral and Dorsal Dartos Tissue of Patients With Hypospadias and Chordee

This study demonstrates that ventral dartos tissue in patients with hypospadias and chordee exhibits significantly lower MMP-1 and higher α-SMA gene expression compared to dorsal tissue, suggesting that regional molecular differences in extracellular matrix remodeling and fibrotic activity contribute to penile curvature.

JOKO PITOYO, Alvarino Alvarino, Afdal Afdal, Indra Jaya, Muhammad Adan Yashar, Naura Alifa Daniesya Pitoyo2026-07-10